Entity Details

Name GSK3B_Thr66
ID P84022
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3BSMAD3Thr66NVNTKCItIPRSLDGphosphorylation
down-regulates quantity by destabilization		18172167SIGNOR-160318
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
→
SMAD3
PThr66		phosphorylation
down-regulates
⊣		SMAD318172167SIGNOR-160318
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		SMAD3SIGNOR-160318