Entity Details

Name XIAP
ID P98170
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKTXIAPSer87VGRHRKVsPNCRFINphosphorylation
up-regulates quantity by stabilization		14645242SIGNOR-244377
RAF1XIAP–phosphorylation
up-regulates activity		16964381SIGNOR-279105
GSK3BXIAPThr180WPDYAHLtPRELASAphosphorylation
up-regulates activity		29678905SIGNOR-277390
AKT1XIAPSer87VGRHRKVsPNCRFINphosphorylation
up-regulates quantity by stabilization		14645242SIGNOR-119488
AKT2XIAPSer87VGRHRKVsPNCRFINphosphorylation
up-regulates		14645242SIGNOR-119492
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKTphosphorylation
up-regulates
→
XIAP
PSer87		phosphorylation
up-regulates
→		XIAP14645242SIGNOR-244377
GSK3Bphosphorylation
up-regulates
→
XIAP
PThr180		phosphorylation
up-regulates
→		XIAP29678905SIGNOR-277390
AKT1phosphorylation
up-regulates
→
XIAP
PSer87		phosphorylation
up-regulates
→		XIAP14645242SIGNOR-119488
AKT2phosphorylation
up-regulates
→
XIAP
PSer87		phosphorylation
up-regulates
→		XIAP14645242SIGNOR-119492
Regulator Mechanism/Effect Target SIGNOR-ID
AKTphosphorylation
→
up-regulates quantity by stabilization 		XIAPSIGNOR-244377
RAF1phosphorylation
→
up-regulates activity 		XIAPSIGNOR-279105
GSK3Bphosphorylation
→
up-regulates activity 		XIAPSIGNOR-277390
AKT1phosphorylation
→
up-regulates quantity by stabilization 		XIAPSIGNOR-119488
AKT2phosphorylation
→
up-regulates 		XIAPSIGNOR-119492