| Name | CDK16 |
| ID | Q00536 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 165-446 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK5 | CDK16 | – | phosphorylation up-regulates activity | 12084709 | SIGNOR-279149 | |
| CyclinY/CDK16 | CDK16 | Ser336 | PPDILLGsTDYSTQI | phosphorylation up-regulates activity | 32723157 | SIGNOR-273006 |
| PRKACA | CDK16 | Ser153 | SRRLRRVsLSEIGFG | phosphorylation down-regulates | 22184064 | SIGNOR-191623 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinY/CDK16 | phosphorylation up-regulates → | CDK16 PSer336 | phosphorylation up-regulates → | CDK16 | 32723157 | SIGNOR-273006 |
| PRKACA | phosphorylation up-regulates → | CDK16 PSer153 | phosphorylation down-regulates ⊣ | CDK16 | 22184064 | SIGNOR-191623 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK5 | phosphorylation → up-regulates activity | CDK16 | SIGNOR-279149 |
| CyclinY/CDK16 | phosphorylation → up-regulates activity | CDK16 | SIGNOR-273006 |
| PRKACA | phosphorylation down-regulates | CDK16 | SIGNOR-191623 |