| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | MDM2 | Tyr405 | STSSSIIySSQEDVK | phosphorylation down-regulates | 21081495 | SIGNOR-169703 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | phosphorylation up-regulates → | MDM2 PTyr405 | phosphorylation down-regulates ⊣ | MDM2 | 21081495 | SIGNOR-169703 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ABL1 | phosphorylation![]() down-regulates | MDM2 | SIGNOR-169703 |