Entity Details

Name AKT_Ser188
ID Q00987
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1MDM2Ser188RKRHKSDsISLSFDEphosphorylation
up-regulates		15169778SIGNOR-124953
AKTMDM2Ser188RKRHKSDsISLSFDEphosphorylation
up-regulates activity		15169778SIGNOR-244300
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
MDM2
PSer188		phosphorylation
up-regulates
→		MDM215169778SIGNOR-124953
AKTphosphorylation
up-regulates
→
MDM2
PSer188		phosphorylation
up-regulates
→		MDM215169778SIGNOR-244300
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
→
up-regulates 		MDM2SIGNOR-124953
AKTphosphorylation
→
up-regulates activity 		MDM2SIGNOR-244300