Entity Details

Name MDM2_Ser370
ID Q00987
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPP1CBMDM2Ser370KKTIVNDsRESCVEEdephosphorylation
up-regulates quantity by stabilization		23277204SIGNOR-248577
PPP1CAMDM2Ser370KKTIVNDsRESCVEEdephosphorylation
up-regulates quantity by stabilization		23277204SIGNOR-248566
PP1MDM2Ser370KKTIVNDsRESCVEEdephosphorylation
up-regulates quantity by stabilization		23277204SIGNOR-264666
PPP1CCMDM2Ser370KKTIVNDsRESCVEEdephosphorylation
up-regulates quantity by stabilization		23277204SIGNOR-248504
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPP1CBdephosphorylation
down-regulates
⊣
MDM2
PSer370		dephosphorylation
down-regulates
⊣		MDM223277204SIGNOR-248577
PPP1CAdephosphorylation
down-regulates
⊣
MDM2
PSer370		dephosphorylation
down-regulates
⊣		MDM223277204SIGNOR-248566
PP1dephosphorylation
down-regulates
⊣
MDM2
PSer370		dephosphorylation
down-regulates
⊣		MDM223277204SIGNOR-264666
PPP1CCdephosphorylation
down-regulates
⊣
MDM2
PSer370		dephosphorylation
down-regulates
⊣		MDM223277204SIGNOR-248504
Regulator Mechanism/Effect Target SIGNOR-ID
PPP1CBdephosphorylation
→
up-regulates quantity by stabilization 		MDM2SIGNOR-248577
PPP1CAdephosphorylation
→
up-regulates quantity by stabilization 		MDM2SIGNOR-248566
PP1dephosphorylation
→
up-regulates quantity by stabilization 		MDM2SIGNOR-264666
PPP1CCdephosphorylation
→
up-regulates quantity by stabilization 		MDM2SIGNOR-248504