| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GRK6 | MC1R | – | phosphorylation down-regulates activity | 15650023 | SIGNOR-252389 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GRK6 | phosphorylation → down-regulates activity | MC1R | SIGNOR-252389 |
