Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
ERK1/2	EWSR1	–		phosphorylation unknown	19076070	SIGNOR-270172
MAPK1	EWSR1	Thr79	QPPTGYTtPTAPQAY	phosphorylation unknown	19076070	SIGNOR-182770
PRKCB	EWSR1	Ser266	SSYGQQSsFRQDHPS	phosphorylation down-regulates activity	9341188	SIGNOR-52854
PRKCA	EWSR1	Ser266	SSYGQQSsFRQDHPS	phosphorylation down-regulates activity	9341188	SIGNOR-52850
MAPK3	EWSR1	Thr79	QPPTGYTtPTAPQAY	phosphorylation unknown	19076070	SIGNOR-182782
MAPK14	EWSR1	Thr79	QPPTGYTtPTAPQAY	phosphorylation unknown	19076070	SIGNOR-182778
MAPK11	EWSR1	Thr79	QPPTGYTtPTAPQAY	phosphorylation unknown	19076070	SIGNOR-182774
Gbeta	EWSR1	–		phosphorylation unknown	19076070	SIGNOR-270062

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAPK1	phosphorylation up-regulates →	EWSR1 PThr79	phosphorylation down-regulates ⊣	EWSR1	19076070	SIGNOR-182770
PRKCB	phosphorylation up-regulates →	EWSR1 PSer266	phosphorylation down-regulates ⊣	EWSR1	9341188	SIGNOR-52854
PRKCA	phosphorylation up-regulates →	EWSR1 PSer266	phosphorylation down-regulates ⊣	EWSR1	9341188	SIGNOR-52850
MAPK3	phosphorylation up-regulates →	EWSR1 PThr79	phosphorylation down-regulates ⊣	EWSR1	19076070	SIGNOR-182782
MAPK14	phosphorylation up-regulates →	EWSR1 PThr79	phosphorylation down-regulates ⊣	EWSR1	19076070	SIGNOR-182778
MAPK11	phosphorylation up-regulates →	EWSR1 PThr79	phosphorylation down-regulates ⊣	EWSR1	19076070	SIGNOR-182774

Regulator	Mechanism/Effect	Target	SIGNOR-ID
ERK1/2	phosphorylation → unknown	EWSR1	SIGNOR-270172
MAPK1	phosphorylation → unknown	EWSR1	SIGNOR-182770
PRKCB	phosphorylation → down-regulates activity	EWSR1	SIGNOR-52854
PRKCA	phosphorylation → down-regulates activity	EWSR1	SIGNOR-52850
MAPK3	phosphorylation → unknown	EWSR1	SIGNOR-182782
MAPK14	phosphorylation → unknown	EWSR1	SIGNOR-182778
MAPK11	phosphorylation → unknown	EWSR1	SIGNOR-182774
Gbeta	phosphorylation → unknown	EWSR1	SIGNOR-270062