| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | EWSR1 | Ser266 | SSYGQQSsFRQDHPS | phosphorylation down-regulates activity | 9341188 | SIGNOR-52854 |
| PRKCA | EWSR1 | Ser266 | SSYGQQSsFRQDHPS | phosphorylation down-regulates activity | 9341188 | SIGNOR-52850 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | phosphorylation up-regulates → | EWSR1 PSer266 | phosphorylation down-regulates ⊣ | EWSR1 | 9341188 | SIGNOR-52854 |
| PRKCA | phosphorylation up-regulates → | EWSR1 PSer266 | phosphorylation down-regulates ⊣ | EWSR1 | 9341188 | SIGNOR-52850 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCB | phosphorylation → down-regulates activity | EWSR1 | SIGNOR-52854 |
| PRKCA | phosphorylation → down-regulates activity | EWSR1 | SIGNOR-52850 |