| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A2 | SPIB | Ser37 | KHSSYPDsEGAPDSL | phosphorylation down-regulates quantity by destabilization | 10618498 | SIGNOR-251042 |
| MAPK3 | SPIB | Thr56 | VAPPVPAtPYEAFDP | phosphorylation unknown | 8632909 | SIGNOR-41800 |
| CSNK2A1 | SPIB | Ser129 | PYPSPVLsEEEDLPL | phosphorylation down-regulates | 10618498 | SIGNOR-73879 |
| CSNK2A2 | SPIB | Ser146 | PALEVSDsESDEALV | phosphorylation down-regulates quantity by destabilization | 10618498 | SIGNOR-251041 |
| CSNK2A1 | SPIB | Ser146 | PALEVSDsESDEALV | phosphorylation down-regulates | 10618498 | SIGNOR-73887 |
| CSNK2A1 | SPIB | Ser144 | DSPALEVsDSESDEA | phosphorylation down-regulates | 10618498 | SIGNOR-73883 |
| CSNK2A2 | SPIB | Ser129 | PYPSPVLsEEEDLPL | phosphorylation down-regulates quantity by destabilization | 10618498 | SIGNOR-251039 |
| CSNK2A1 | SPIB | Ser37 | KHSSYPDsEGAPDSL | phosphorylation down-regulates | 10618498 | SIGNOR-73891 |
| CSNK2A2 | SPIB | Ser144 | DSPALEVsDSESDEA | phosphorylation down-regulates quantity by destabilization | 10618498 | SIGNOR-251040 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A2 | phosphorylation up-regulates → | SPIB PSer37 | phosphorylation down-regulates ⊣ | SPIB | 10618498 | SIGNOR-251042 |
| MAPK3 | phosphorylation up-regulates → | SPIB PThr56 | phosphorylation down-regulates ⊣ | SPIB | 8632909 | SIGNOR-41800 |
| CSNK2A1 | phosphorylation up-regulates → | SPIB PSer129 | phosphorylation down-regulates ⊣ | SPIB | 10618498 | SIGNOR-73879 |
| CSNK2A2 | phosphorylation up-regulates → | SPIB PSer146 | phosphorylation down-regulates ⊣ | SPIB | 10618498 | SIGNOR-251041 |
| CSNK2A1 | phosphorylation up-regulates → | SPIB PSer146 | phosphorylation down-regulates ⊣ | SPIB | 10618498 | SIGNOR-73887 |
| CSNK2A1 | phosphorylation up-regulates → | SPIB PSer144 | phosphorylation down-regulates ⊣ | SPIB | 10618498 | SIGNOR-73883 |
| CSNK2A2 | phosphorylation up-regulates → | SPIB PSer129 | phosphorylation down-regulates ⊣ | SPIB | 10618498 | SIGNOR-251039 |
| CSNK2A1 | phosphorylation up-regulates → | SPIB PSer37 | phosphorylation down-regulates ⊣ | SPIB | 10618498 | SIGNOR-73891 |
| CSNK2A2 | phosphorylation up-regulates → | SPIB PSer144 | phosphorylation down-regulates ⊣ | SPIB | 10618498 | SIGNOR-251040 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A2 | phosphorylation down-regulates quantity by destabilization | SPIB | SIGNOR-251042 |
| MAPK3 | phosphorylation → unknown | SPIB | SIGNOR-41800 |
| CSNK2A1 | phosphorylation down-regulates | SPIB | SIGNOR-73879 |
| CSNK2A2 | phosphorylation down-regulates quantity by destabilization | SPIB | SIGNOR-251041 |
| CSNK2A1 | phosphorylation down-regulates | SPIB | SIGNOR-73887 |
| CSNK2A1 | phosphorylation down-regulates | SPIB | SIGNOR-73883 |
| CSNK2A2 | phosphorylation down-regulates quantity by destabilization | SPIB | SIGNOR-251039 |
| CSNK2A1 | phosphorylation down-regulates | SPIB | SIGNOR-73891 |
| CSNK2A2 | phosphorylation down-regulates quantity by destabilization | SPIB | SIGNOR-251040 |
