| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IKBKB | RELA | Ser468 | AVFTDLAsVDNSEFQ | phosphorylation up-regulates activity | 16046471 | SIGNOR-138903 |
| GSK3B | RELA | Ser468 | AVFTDLAsVDNSEFQ | phosphorylation up-regulates | 16407239 | SIGNOR-143581 |
| GSK3B | RELA | Ser468 | AVFTDLAsVDNSEFQ | phosphorylation up-regulates | 17183360 | SIGNOR-151422 |
| IKBKE | RELA | Ser468 | AVFTDLAsVDNSEFQ | phosphorylation up-regulates | 15489227 | SIGNOR-129939 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IKBKB | phosphorylation up-regulates → | RELA PSer468 | phosphorylation up-regulates → | RELA | 16046471 | SIGNOR-138903 |
| GSK3B | phosphorylation up-regulates → | RELA PSer468 | phosphorylation up-regulates → | RELA | 16407239 | SIGNOR-143581 |
| GSK3B | phosphorylation up-regulates → | RELA PSer468 | phosphorylation up-regulates → | RELA | 17183360 | SIGNOR-151422 |
| IKBKE | phosphorylation up-regulates → | RELA PSer468 | phosphorylation up-regulates → | RELA | 15489227 | SIGNOR-129939 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| IKBKB | phosphorylation → up-regulates activity | RELA | SIGNOR-138903 |
| GSK3B | phosphorylation → up-regulates | RELA | SIGNOR-143581 |
| GSK3B | phosphorylation → up-regulates | RELA | SIGNOR-151422 |
| IKBKE | phosphorylation → up-regulates | RELA | SIGNOR-129939 |
