| Name | PRKCZ |
| ID | Q05513 |
| Role | kinase |
| Enzymatic Domains |
PB1 15-98 PROSITE-ProRule
Protein kinase 252-518 PROSITE-ProRule
AGC-kinase C-terminal 519-590 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCZ | ARHGDIA | – | phosphorylation up-regulates activity | 17389234 | SIGNOR-280089 | |
| PRKCZ | ADARB1 | Ser216 | SASPVPAsLAQPPLP | phosphorylation up-regulates activity | 29694894 | SIGNOR-277391 |
| PRKCZ | SP1 | Ser641 | GKVYGKTsHLRAHLR | phosphorylation up-regulates | 19464346 | SIGNOR-185741 |
| PRKCZ | PIAS4 | Ser18 | MVMSFRVsDLQMLLG | phosphorylation down-regulates quantity by destabilization | 27162139 | SIGNOR-275513 |
| PRKCZ | WWC1 | Ser978 | KRPSSVKsLRSERLI | phosphorylation unknown | 15081397 | SIGNOR-249263 |
| PRKCZ | PARD3 | Ser827 | REGFGRQsMSEKRTK | phosphorylation up-regulates | 12390250 | SIGNOR-94523 |
| PRKCZ | HABP4 | Thr375 | GRGARGGtRGGRGRI | phosphorylation down-regulates activity | 14699138 | SIGNOR-249257 |
| PRKCZ | GRM5 | Thr841 | RSAFTTStVVRMHVG | phosphorylation up-regulates activity | 15894802 | SIGNOR-249291 |
| PRKCZ | ADD1 | Ser726 | KKKFRTPsFLKKSKK | phosphorylation up-regulates | 8810272 | SIGNOR-43834 |
| PRKCZ | MARK2 | Thr596 | RGVSSRStFHAGQLR | phosphorylation down-regulates | 15084291 | SIGNOR-124217 |
| PRKCZ | IKBKB | Ser177 | AKELDQGsLCTSFVG | phosphorylation up-regulates activity | 10022904 | SIGNOR-249015 |
| PRKCZ | NCF1 | Ser359 | EERQTQRsKPQPAVP | phosphorylation up-regulates | 12056906 | SIGNOR-89280 |
| PRKCZ | ADD2 | Ser713 | KKKFRTPsFLKKSKK | phosphorylation down-regulates | 16116087 | SIGNOR-139914 |
| PRKCZ | GRM5 | Ser840 | VRSAFTTsTVVRMHV | phosphorylation up-regulates activity | 15894802 | SIGNOR-249284 |
| PRKCZ | AQP9 | Ser11 | EGAEKGKsFKQRLVL | phosphorylation up-regulates | 21873454 | SIGNOR-176278 |
| PRKCZ | YAP1 | Ser109 | KSHSRQAsTDAGTAG | phosphorylation down-regulates quantity by destabilization | 25660024 | SIGNOR-276876 |
| PRKCZ | GSTP1 | Ser43 | VETWQEGsLKASCLY | phosphorylation up-regulates activity | 15604283 | SIGNOR-276016 |
| PRKCZ | NOS3 | Thr495 | TGITRKKtFKEVANA | phosphorylation down-regulates activity | 24379783 | SIGNOR-251637 |
| PRKCZ | CTNNB1 | Ser675 | QDYKKRLsVELTSSL | phosphorylation down-regulates quantity by destabilization | 25660024 | SIGNOR-276880 |
| PRKCZ | AKT2 | Thr309 | SDGATMKtFCGTPEY | phosphorylation up-regulates activity | 9512493 | SIGNOR-248997 |
| PRKCZ | PSEN1 | Ser346 | EWEAQRDsHLGPHRS | phosphorylation up-regulates activity | 14576165 | SIGNOR-249239 |
| PRKCZ | STK11 | Ser428 | SSKIRRLsACKQQ | phosphorylation up-regulates activity | 18250273 | SIGNOR-160681 |
| PRKCZ | YWHAB | Thr143 | SGDNKQTtVSNSQQA | phosphorylation down-regulates activity | 10620507 | SIGNOR-249035 |
| PRKCZ | NfKb-p65/p50 | – | phosphorylation up-regulates | 17183360 | SIGNOR-217370 | |
| PRKCZ | SP1 | Thr668 | SYCGKRFtRSDELQR | phosphorylation up-regulates | 18258854 | SIGNOR-160770 |
| PRKCZ | MAPT | Ser324 | RHLSNVSsTGSIDMV | phosphorylation down-regulates activity | 10090741 | SIGNOR-275447 |
| PRKCZ | NCF1 | Ser304 | GAPPRRSsIRNAHSI | phosphorylation up-regulates | 12056906 | SIGNOR-89260 |
| PRKCZ | NCF1 | Ser320 | QRSRKRLsQDAYRRN | phosphorylation up-regulates | 12056906 | SIGNOR-89268 |
| PRKCZ | NCF1 | Ser379 | DLILNRCsESTKRKL | phosphorylation up-regulates | 12056906 | SIGNOR-89288 |
| PRKCZ | VIM | Ser34 | SRSYVTTsTRTYSLG | phosphorylation up-regulates activity | 33525953 | SIGNOR-277622 |
| PRKCZ | SP1 | Ser670 | CGKRFTRsDELQRHK | phosphorylation up-regulates | 18258854 | SIGNOR-160766 |
| PRKCZ | PTPN7 | Ser246 | QYQEERRsVKHILFS | phosphorylation up-regulates activity | 16479000 | SIGNOR-276047 |
| PRKCZ | NREP | Ser59 | LGSSELRsPRISYLH | phosphorylation down-regulates quantity by destabilization | 16229809 | SIGNOR-273831 |
| PRKCZ | PARD6A | Ser345 | RGDGSGFsL | phosphorylation up-regulates quantity by stabilization | 23249950 | SIGNOR-276433 |
| PRKCZ | TRAF2 | Ser55 | QCGHRYCsFCLASIL | phosphorylation unknown | 19336568 | SIGNOR-184941 |
| PRKCZ | ATP1A1 | Ser16 | KYEPAAVsEQGDKKG | phosphorylation up-regulates activity | 12671055 | SIGNOR-263181 |
| PRKCZ | MARK3 | Thr564 | RGTASRStFHGQPRE | phosphorylation down-regulates | 15084291 | SIGNOR-124221 |
| PRKCZ | IKBKB | Ser181 | DQGSLCTsFVGTLQY | phosphorylation up-regulates activity | 10022904 | SIGNOR-249016 |
| PRKCZ | CHAT | Ser594 | HKAAVPAsEKLLLLK | phosphorylation up-regulates | 15381704 | SIGNOR-129340 |
| PRKCZ | RELA | Ser311 | RTYETFKsIMKKSPF | phosphorylation up-regulates | 17183360 | SIGNOR-151432 |
| PRKCZ | SP1 | Ser641 | GKVYGKTsHLRAHLR | phosphorylation up-regulates | 16943418 | SIGNOR-149287 |
| PRKCZ | MGluR | – | phosphorylation up-regulates activity | 15894802 | SIGNOR-270274 | |
| PRKCZ | HABP4 | Thr354 | RKPANDItSQLEINF | phosphorylation down-regulates activity | 14699138 | SIGNOR-249251 |
| PRKCZ | NCF1 | Ser370 | PAVPPRPsADLILNR | phosphorylation up-regulates | 12056906 | SIGNOR-89284 |
| PRKCZ | CHAT | Ser558 | VPTYESAsIRRFQEG | phosphorylation up-regulates | 15381704 | SIGNOR-129336 |
| PRKCZ | MYH10 | Ser1937 | RGGPISFsSSRSGRR | phosphorylation down-regulates | 16611744 | SIGNOR-146100 |
| PRKCZ | PLA2G4A | Thr376 | GSKFFMGtVVKKYEE | phosphorylation up-regulates activity | 32559461 | SIGNOR-277518 |
| PRKCZ | SNAI1 | Ser249 | ARTFSRMsLLHKHQE | phosphorylation down-regulates quantity by destabilization | 30804505 | SIGNOR-277437 |
| PRKCZ | AKT3 | Ser472 | RPHFPQFsYSASGRE | phosphorylation up-regulates activity | 12162751 | SIGNOR-249153 |
| PRKCZ | ADD1 | Ser726 | KKKFRTPsFLKKSKK | phosphorylation up-regulates | 9679146 | SIGNOR-59303 |
| PRKCZ | SP1 | Thr681 | QRHKRTHtGEKKFAC | phosphorylation up-regulates | 18258854 | SIGNOR-160774 |
| PRKCZ | ADARB1 | Ser211 | GDLSLSAsPVPASLA | phosphorylation up-regulates activity | 29694894 | SIGNOR-277392 |
| PRKCZ | IRS1 | Ser1101 | GCRRRHSsETFSSTP | phosphorylation down-regulates quantity by destabilization | 17360977 | SIGNOR-236022 |
| PRKCZ | NCF1 | Ser303 | RGAPPRRsSIRNAHS | phosphorylation up-regulates | 12056906 | SIGNOR-89252 |
| PRKCZ | NR1H4 | Thr456 | GRLTELRtFNHHHAE | phosphorylation up-regulates | 18668687 | SIGNOR-179771 |
| PRKCZ | CTNNB1 | Ser45 | GATTTAPsLSGKGNP | phosphorylation down-regulates quantity by destabilization | 25660024 | SIGNOR-276878 |
| PRKCZ | MAPK7 | – | phosphorylation down-regulates activity | 20538799 | SIGNOR-280090 | |
| PRKCZ | MAP1LC3B | Thr50 | QLPVLDKtKFLVPDH | phosphorylation down-regulates activity | 31857374 | SIGNOR-273906 |
| PRKCZ | PPP1R14A | Thr38 | QKRHARVtVKYDRRE | phosphorylation up-regulates activity | 32471307 | SIGNOR-249261 |
| PRKCZ | NCF1 | Ser315 | AHSIHQRsRKRLSQD | phosphorylation up-regulates | 12056906 | SIGNOR-89264 |
| PRKCZ | IRS1 | Ser307 | TRRSRTEsITATSPA | phosphorylation down-regulates activity | 15069075 | SIGNOR-236760 |
| PRKCZ | BAX | Ser184 | VAGVLTAsLTIWKKM | phosphorylation down-regulates activity | 17525161 | SIGNOR-155111 |
| PRKCZ | YAP1 | Thr110 | SHSRQAStDAGTAGA | phosphorylation down-regulates quantity by destabilization | 25660024 | SIGNOR-276877 |
| PRKCZ | GSTP1 | Ser185 | SAYVGRLsARPKLKA | phosphorylation up-regulates activity | 15604283 | SIGNOR-276017 |
| PRKCZ | CTNNB1 | Ser552 | QDTQRRTsMGGTQQQ | phosphorylation down-regulates quantity by destabilization | 25660024 | SIGNOR-276879 |
| PRKCZ | PRKCZ | Thr560 | TSEPVQLtPDDEDAI | phosphorylation up-regulates | 11141077 | SIGNOR-85505 |
| PRKCZ | AKT3 | Thr305 | TDAATMKtFCGTPEY | phosphorylation up-regulates activity | 9512493 | SIGNOR-248996 |
| PRKCZ | STK11 | Ser307 | IRQIRQHsWFRKKHP | phosphorylation up-regulates | 19414597 | SIGNOR-185640 |
| PRKCZ | IRS1 | Ser323 | MVGGKPGsFRVRASS | phosphorylation down-regulates | 15069075 | SIGNOR-123738 |
| PRKCZ | GSK3B | Ser9 | SGRPRTTsFAESCKP | phosphorylation down-regulates | 14657655 | SIGNOR-119889 |
| PRKCZ | WWC1 | Ser975 | VRMKRPSsVKSLRSE | phosphorylation unknown | 15081397 | SIGNOR-249262 |
| PRKCZ | CASP9 | Ser144 | GDVGALEsLRGNADL | phosphorylation down-regulates | 16287866 | SIGNOR-141629 |
| PRKCZ | NCF1 | Ser328 | QDAYRRNsVRFLQQR | phosphorylation up-regulates | 12056906 | SIGNOR-89272 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCZ | phosphorylation up-regulates → | ADARB1 PSer216 | phosphorylation up-regulates → | ADARB1 | 29694894 | SIGNOR-277391 |
| PRKCZ | phosphorylation up-regulates → | SP1 PSer641 | phosphorylation up-regulates → | SP1 | 19464346 | SIGNOR-185741 |
| PRKCZ | phosphorylation up-regulates → | PIAS4 PSer18 | phosphorylation down-regulates ⊣ | PIAS4 | 27162139 | SIGNOR-275513 |
| PRKCZ | phosphorylation up-regulates → | WWC1 PSer978 | phosphorylation down-regulates ⊣ | WWC1 | 15081397 | SIGNOR-249263 |
| PRKCZ | phosphorylation up-regulates → | PARD3 PSer827 | phosphorylation up-regulates → | PARD3 | 12390250 | SIGNOR-94523 |
| PRKCZ | phosphorylation up-regulates → | HABP4 PThr375 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249257 |
| PRKCZ | phosphorylation up-regulates → | GRM5 PThr841 | phosphorylation up-regulates → | GRM5 | 15894802 | SIGNOR-249291 |
| PRKCZ | phosphorylation up-regulates → | ADD1 PSer726 | phosphorylation up-regulates → | ADD1 | 8810272 | SIGNOR-43834 |
| PRKCZ | phosphorylation up-regulates → | MARK2 PThr596 | phosphorylation down-regulates ⊣ | MARK2 | 15084291 | SIGNOR-124217 |
| PRKCZ | phosphorylation up-regulates → | IKBKB PSer177 | phosphorylation up-regulates → | IKBKB | 10022904 | SIGNOR-249015 |
| PRKCZ | phosphorylation up-regulates → | NCF1 PSer359 | phosphorylation up-regulates → | NCF1 | 12056906 | SIGNOR-89280 |
| PRKCZ | phosphorylation up-regulates → | ADD2 PSer713 | phosphorylation down-regulates ⊣ | ADD2 | 16116087 | SIGNOR-139914 |
| PRKCZ | phosphorylation up-regulates → | GRM5 PSer840 | phosphorylation up-regulates → | GRM5 | 15894802 | SIGNOR-249284 |
| PRKCZ | phosphorylation up-regulates → | AQP9 PSer11 | phosphorylation up-regulates → | AQP9 | 21873454 | SIGNOR-176278 |
| PRKCZ | phosphorylation up-regulates → | YAP1 PSer109 | phosphorylation down-regulates ⊣ | YAP1 | 25660024 | SIGNOR-276876 |
| PRKCZ | phosphorylation up-regulates → | GSTP1 PSer43 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276016 |
| PRKCZ | phosphorylation up-regulates → | NOS3 PThr495 | phosphorylation down-regulates ⊣ | NOS3 | 24379783 | SIGNOR-251637 |
| PRKCZ | phosphorylation up-regulates → | CTNNB1 PSer675 | phosphorylation down-regulates ⊣ | CTNNB1 | 25660024 | SIGNOR-276880 |
| PRKCZ | phosphorylation up-regulates → | AKT2 PThr309 | phosphorylation up-regulates → | AKT2 | 9512493 | SIGNOR-248997 |
| PRKCZ | phosphorylation up-regulates → | PSEN1 PSer346 | phosphorylation up-regulates → | PSEN1 | 14576165 | SIGNOR-249239 |
| PRKCZ | phosphorylation up-regulates → | STK11 PSer428 | phosphorylation up-regulates → | STK11 | 18250273 | SIGNOR-160681 |
| PRKCZ | phosphorylation up-regulates → | YWHAB PThr143 | phosphorylation down-regulates ⊣ | YWHAB | 10620507 | SIGNOR-249035 |
| PRKCZ | phosphorylation up-regulates → | SP1 PThr668 | phosphorylation up-regulates → | SP1 | 18258854 | SIGNOR-160770 |
| PRKCZ | phosphorylation up-regulates → | MAPT PSer324 | phosphorylation down-regulates ⊣ | MAPT | 10090741 | SIGNOR-275447 |
| PRKCZ | phosphorylation up-regulates → | NCF1 PSer304 | phosphorylation up-regulates → | NCF1 | 12056906 | SIGNOR-89260 |
| PRKCZ | phosphorylation up-regulates → | NCF1 PSer320 | phosphorylation up-regulates → | NCF1 | 12056906 | SIGNOR-89268 |
| PRKCZ | phosphorylation up-regulates → | NCF1 PSer379 | phosphorylation up-regulates → | NCF1 | 12056906 | SIGNOR-89288 |
| PRKCZ | phosphorylation up-regulates → | VIM PSer34 | phosphorylation up-regulates → | VIM | 33525953 | SIGNOR-277622 |
| PRKCZ | phosphorylation up-regulates → | SP1 PSer670 | phosphorylation up-regulates → | SP1 | 18258854 | SIGNOR-160766 |
| PRKCZ | phosphorylation up-regulates → | PTPN7 PSer246 | phosphorylation up-regulates → | PTPN7 | 16479000 | SIGNOR-276047 |
| PRKCZ | phosphorylation up-regulates → | NREP PSer59 | phosphorylation down-regulates ⊣ | NREP | 16229809 | SIGNOR-273831 |
| PRKCZ | phosphorylation up-regulates → | PARD6A PSer345 | phosphorylation up-regulates → | PARD6A | 23249950 | SIGNOR-276433 |
| PRKCZ | phosphorylation up-regulates → | TRAF2 PSer55 | phosphorylation down-regulates ⊣ | TRAF2 | 19336568 | SIGNOR-184941 |
| PRKCZ | phosphorylation up-regulates → | ATP1A1 PSer16 | phosphorylation up-regulates → | ATP1A1 | 12671055 | SIGNOR-263181 |
| PRKCZ | phosphorylation up-regulates → | MARK3 PThr564 | phosphorylation down-regulates ⊣ | MARK3 | 15084291 | SIGNOR-124221 |
| PRKCZ | phosphorylation up-regulates → | IKBKB PSer181 | phosphorylation up-regulates → | IKBKB | 10022904 | SIGNOR-249016 |
| PRKCZ | phosphorylation up-regulates → | CHAT PSer594 | phosphorylation up-regulates → | CHAT | 15381704 | SIGNOR-129340 |
| PRKCZ | phosphorylation up-regulates → | RELA PSer311 | phosphorylation up-regulates → | RELA | 17183360 | SIGNOR-151432 |
| PRKCZ | phosphorylation up-regulates → | SP1 PSer641 | phosphorylation up-regulates → | SP1 | 16943418 | SIGNOR-149287 |
| PRKCZ | phosphorylation up-regulates → | HABP4 PThr354 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249251 |
| PRKCZ | phosphorylation up-regulates → | NCF1 PSer370 | phosphorylation up-regulates → | NCF1 | 12056906 | SIGNOR-89284 |
| PRKCZ | phosphorylation up-regulates → | CHAT PSer558 | phosphorylation up-regulates → | CHAT | 15381704 | SIGNOR-129336 |
| PRKCZ | phosphorylation up-regulates → | MYH10 PSer1937 | phosphorylation down-regulates ⊣ | MYH10 | 16611744 | SIGNOR-146100 |
| PRKCZ | phosphorylation up-regulates → | PLA2G4A PThr376 | phosphorylation up-regulates → | PLA2G4A | 32559461 | SIGNOR-277518 |
| PRKCZ | phosphorylation up-regulates → | SNAI1 PSer249 | phosphorylation down-regulates ⊣ | SNAI1 | 30804505 | SIGNOR-277437 |
| PRKCZ | phosphorylation up-regulates → | AKT3 PSer472 | phosphorylation up-regulates → | AKT3 | 12162751 | SIGNOR-249153 |
| PRKCZ | phosphorylation up-regulates → | ADD1 PSer726 | phosphorylation up-regulates → | ADD1 | 9679146 | SIGNOR-59303 |
| PRKCZ | phosphorylation up-regulates → | SP1 PThr681 | phosphorylation up-regulates → | SP1 | 18258854 | SIGNOR-160774 |
| PRKCZ | phosphorylation up-regulates → | ADARB1 PSer211 | phosphorylation up-regulates → | ADARB1 | 29694894 | SIGNOR-277392 |
| PRKCZ | phosphorylation up-regulates → | IRS1 PSer1101 | phosphorylation down-regulates ⊣ | IRS1 | 17360977 | SIGNOR-236022 |
| PRKCZ | phosphorylation up-regulates → | NCF1 PSer303 | phosphorylation up-regulates → | NCF1 | 12056906 | SIGNOR-89252 |
| PRKCZ | phosphorylation up-regulates → | NR1H4 PThr456 | phosphorylation up-regulates → | NR1H4 | 18668687 | SIGNOR-179771 |
| PRKCZ | phosphorylation up-regulates → | CTNNB1 PSer45 | phosphorylation down-regulates ⊣ | CTNNB1 | 25660024 | SIGNOR-276878 |
| PRKCZ | phosphorylation up-regulates → | MAP1LC3B PThr50 | phosphorylation down-regulates ⊣ | MAP1LC3B | 31857374 | SIGNOR-273906 |
| PRKCZ | phosphorylation up-regulates → | PPP1R14A PThr38 | phosphorylation up-regulates → | PPP1R14A | 32471307 | SIGNOR-249261 |
| PRKCZ | phosphorylation up-regulates → | NCF1 PSer315 | phosphorylation up-regulates → | NCF1 | 12056906 | SIGNOR-89264 |
| PRKCZ | phosphorylation up-regulates → | IRS1 PSer307 | phosphorylation down-regulates ⊣ | IRS1 | 15069075 | SIGNOR-236760 |
| PRKCZ | phosphorylation up-regulates → | BAX PSer184 | phosphorylation down-regulates ⊣ | BAX | 17525161 | SIGNOR-155111 |
| PRKCZ | phosphorylation up-regulates → | YAP1 PThr110 | phosphorylation down-regulates ⊣ | YAP1 | 25660024 | SIGNOR-276877 |
| PRKCZ | phosphorylation up-regulates → | GSTP1 PSer185 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276017 |
| PRKCZ | phosphorylation up-regulates → | CTNNB1 PSer552 | phosphorylation down-regulates ⊣ | CTNNB1 | 25660024 | SIGNOR-276879 |
| PRKCZ | phosphorylation up-regulates → | PRKCZ PThr560 | phosphorylation up-regulates → | PRKCZ | 11141077 | SIGNOR-85505 |
| PRKCZ | phosphorylation up-regulates → | AKT3 PThr305 | phosphorylation up-regulates → | AKT3 | 9512493 | SIGNOR-248996 |
| PRKCZ | phosphorylation up-regulates → | STK11 PSer307 | phosphorylation up-regulates → | STK11 | 19414597 | SIGNOR-185640 |
| PRKCZ | phosphorylation up-regulates → | IRS1 PSer323 | phosphorylation down-regulates ⊣ | IRS1 | 15069075 | SIGNOR-123738 |
| PRKCZ | phosphorylation up-regulates → | GSK3B PSer9 | phosphorylation down-regulates ⊣ | GSK3B | 14657655 | SIGNOR-119889 |
| PRKCZ | phosphorylation up-regulates → | WWC1 PSer975 | phosphorylation down-regulates ⊣ | WWC1 | 15081397 | SIGNOR-249262 |
| PRKCZ | phosphorylation up-regulates → | CASP9 PSer144 | phosphorylation down-regulates ⊣ | CASP9 | 16287866 | SIGNOR-141629 |
| PRKCZ | phosphorylation up-regulates → | NCF1 PSer328 | phosphorylation up-regulates → | NCF1 | 12056906 | SIGNOR-89272 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCZ | phosphorylation → up-regulates activity | ARHGDIA | SIGNOR-280089 |
| PRKCZ | phosphorylation → up-regulates activity | ADARB1 | SIGNOR-277391 |
| PRKCZ | phosphorylation → up-regulates | SP1 | SIGNOR-185741 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | PIAS4 | SIGNOR-275513 |
| PRKCZ | phosphorylation → unknown | WWC1 | SIGNOR-249263 |
| PRKCZ | phosphorylation → up-regulates | PARD3 | SIGNOR-94523 |
| PRKCZ | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249257 |
| PRKCZ | phosphorylation → up-regulates activity | GRM5 | SIGNOR-249291 |
| PRKCZ | phosphorylation → up-regulates | ADD1 | SIGNOR-43834 |
| PRKCZ | phosphorylation down-regulates | MARK2 | SIGNOR-124217 |
| PRKCZ | phosphorylation → up-regulates activity | IKBKB | SIGNOR-249015 |
| PRKCZ | phosphorylation → up-regulates | NCF1 | SIGNOR-89280 |
| PRKCZ | phosphorylation down-regulates | ADD2 | SIGNOR-139914 |
| PRKCZ | phosphorylation → up-regulates activity | GRM5 | SIGNOR-249284 |
| PRKCZ | phosphorylation → up-regulates | AQP9 | SIGNOR-176278 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-276876 |
| PRKCZ | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276016 |
| PRKCZ | phosphorylation → down-regulates activity | NOS3 | SIGNOR-251637 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | CTNNB1 | SIGNOR-276880 |
| PRKCZ | phosphorylation → up-regulates activity | AKT2 | SIGNOR-248997 |
| PRKCZ | phosphorylation → up-regulates activity | PSEN1 | SIGNOR-249239 |
| PRKCZ | phosphorylation → up-regulates activity | STK11 | SIGNOR-160681 |
| PRKCZ | phosphorylation → down-regulates activity | YWHAB | SIGNOR-249035 |
| PRKCZ | phosphorylation → up-regulates | NfKb-p65/p50 | SIGNOR-217370 |
| PRKCZ | phosphorylation → up-regulates | SP1 | SIGNOR-160770 |
| PRKCZ | phosphorylation → down-regulates activity | MAPT | SIGNOR-275447 |
| PRKCZ | phosphorylation → up-regulates | NCF1 | SIGNOR-89260 |
| PRKCZ | phosphorylation → up-regulates | NCF1 | SIGNOR-89268 |
| PRKCZ | phosphorylation → up-regulates | NCF1 | SIGNOR-89288 |
| PRKCZ | phosphorylation → up-regulates activity | VIM | SIGNOR-277622 |
| PRKCZ | phosphorylation → up-regulates | SP1 | SIGNOR-160766 |
| PRKCZ | phosphorylation → up-regulates activity | PTPN7 | SIGNOR-276047 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | NREP | SIGNOR-273831 |
| PRKCZ | phosphorylation → up-regulates quantity by stabilization | PARD6A | SIGNOR-276433 |
| PRKCZ | phosphorylation → unknown | TRAF2 | SIGNOR-184941 |
| PRKCZ | phosphorylation → up-regulates activity | ATP1A1 | SIGNOR-263181 |
| PRKCZ | phosphorylation down-regulates | MARK3 | SIGNOR-124221 |
| PRKCZ | phosphorylation → up-regulates activity | IKBKB | SIGNOR-249016 |
| PRKCZ | phosphorylation → up-regulates | CHAT | SIGNOR-129340 |
| PRKCZ | phosphorylation → up-regulates | RELA | SIGNOR-151432 |
| PRKCZ | phosphorylation → up-regulates | SP1 | SIGNOR-149287 |
| PRKCZ | phosphorylation → up-regulates activity | MGluR | SIGNOR-270274 |
| PRKCZ | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249251 |
| PRKCZ | phosphorylation → up-regulates | NCF1 | SIGNOR-89284 |
| PRKCZ | phosphorylation → up-regulates | CHAT | SIGNOR-129336 |
| PRKCZ | phosphorylation down-regulates | MYH10 | SIGNOR-146100 |
| PRKCZ | phosphorylation → up-regulates activity | PLA2G4A | SIGNOR-277518 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | SNAI1 | SIGNOR-277437 |
| PRKCZ | phosphorylation → up-regulates activity | AKT3 | SIGNOR-249153 |
| PRKCZ | phosphorylation → up-regulates | ADD1 | SIGNOR-59303 |
| PRKCZ | phosphorylation → up-regulates | SP1 | SIGNOR-160774 |
| PRKCZ | phosphorylation → up-regulates activity | ADARB1 | SIGNOR-277392 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | IRS1 | SIGNOR-236022 |
| PRKCZ | phosphorylation → up-regulates | NCF1 | SIGNOR-89252 |
| PRKCZ | phosphorylation → up-regulates | NR1H4 | SIGNOR-179771 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | CTNNB1 | SIGNOR-276878 |
| PRKCZ | phosphorylation → down-regulates activity | MAPK7 | SIGNOR-280090 |
| PRKCZ | phosphorylation → down-regulates activity | MAP1LC3B | SIGNOR-273906 |
| PRKCZ | phosphorylation → up-regulates activity | PPP1R14A | SIGNOR-249261 |
| PRKCZ | phosphorylation → up-regulates | NCF1 | SIGNOR-89264 |
| PRKCZ | phosphorylation → down-regulates activity | IRS1 | SIGNOR-236760 |
| PRKCZ | phosphorylation → down-regulates activity | BAX | SIGNOR-155111 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-276877 |
| PRKCZ | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276017 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | CTNNB1 | SIGNOR-276879 |
| PRKCZ | phosphorylation → up-regulates | PRKCZ | SIGNOR-85505 |
| PRKCZ | phosphorylation → up-regulates activity | AKT3 | SIGNOR-248996 |
| PRKCZ | phosphorylation → up-regulates | STK11 | SIGNOR-185640 |
| PRKCZ | phosphorylation down-regulates | IRS1 | SIGNOR-123738 |
| PRKCZ | phosphorylation down-regulates | GSK3B | SIGNOR-119889 |
| PRKCZ | phosphorylation → unknown | WWC1 | SIGNOR-249262 |
| PRKCZ | phosphorylation down-regulates | CASP9 | SIGNOR-141629 |
| PRKCZ | phosphorylation → up-regulates | NCF1 | SIGNOR-89272 |