| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CB | PRKCD | Ser645 | LNEKARLsYSDKNLI | dephosphorylation down-regulates activity | 11959144 | SIGNOR-248595 |
| PPP2CA | PRKCD | Ser645 | LNEKARLsYSDKNLI | dephosphorylation down-regulates activity | 11959144 | SIGNOR-248638 |
| PRKCD | PRKCD | Ser645 | LNEKARLsYSDKNLI | phosphorylation up-regulates | 15731106 | SIGNOR-134207 |
| PRKCD | PRKCD | Ser645 | LNEKARLsYSDKNLI | phosphorylation up-regulates | 9305920 | SIGNOR-51000 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CB | dephosphorylation down-regulates ⊣ | PRKCD PSer645 | dephosphorylation up-regulates → | PRKCD | 11959144 | SIGNOR-248595 |
| PPP2CA | dephosphorylation down-regulates ⊣ | PRKCD PSer645 | dephosphorylation up-regulates → | PRKCD | 11959144 | SIGNOR-248638 |
| PRKCD | phosphorylation up-regulates → | PRKCD PSer645 | phosphorylation up-regulates → | PRKCD | 15731106 | SIGNOR-134207 |
| PRKCD | phosphorylation up-regulates → | PRKCD PSer645 | phosphorylation up-regulates → | PRKCD | 9305920 | SIGNOR-51000 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2CB | dephosphorylation → down-regulates activity | PRKCD | SIGNOR-248595 |
| PPP2CA | dephosphorylation → down-regulates activity | PRKCD | SIGNOR-248638 |
| PRKCD | phosphorylation → up-regulates | PRKCD | SIGNOR-134207 |
| PRKCD | phosphorylation → up-regulates | PRKCD | SIGNOR-51000 |
