| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | CALD1 | Ser789 | QSVDKVTsPTKV | phosphorylation down-regulates | 10514499 | SIGNOR-71045 |
| MAPK1 | CALD1 | Ser789 | QSVDKVTsPTKV | phosphorylation down-regulates | 10514499 | SIGNOR-71037 |
| CDK5 | CALD1 | Ser789 | QSVDKVTsPTKV | phosphorylation down-regulates quantity by destabilization | 21791703 | SIGNOR-280215 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | CALD1 PSer789 | phosphorylation down-regulates ⊣ | CALD1 | 10514499 | SIGNOR-71045 |
| MAPK1 | phosphorylation up-regulates → | CALD1 PSer789 | phosphorylation down-regulates ⊣ | CALD1 | 10514499 | SIGNOR-71037 |
| CDK5 | phosphorylation up-regulates → | CALD1 PSer789 | phosphorylation down-regulates ⊣ | CALD1 | 21791703 | SIGNOR-280215 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation down-regulates | CALD1 | SIGNOR-71045 |
| MAPK1 | phosphorylation down-regulates | CALD1 | SIGNOR-71037 |
| CDK5 | phosphorylation down-regulates quantity by destabilization | CALD1 | SIGNOR-280215 |
