Entity Details

Name EGFR_Tyr542
ID Q06124
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PDGFRBPTPN11Tyr542SKRKGHEyTNIKYSLphosphorylation
up-regulates activity		8041791SIGNOR-250260
EGFRPTPN11Tyr542SKRKGHEyTNIKYSLphosphorylation
up-regulates activity		19427850SIGNOR-279460
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PDGFRBphosphorylation
up-regulates
→
PTPN11
PTyr542		phosphorylation
up-regulates
→		PTPN118041791SIGNOR-250260
EGFRphosphorylation
up-regulates
→
PTPN11
PTyr542		phosphorylation
up-regulates
→		PTPN1119427850SIGNOR-279460
Regulator Mechanism/Effect Target SIGNOR-ID
PDGFRBphosphorylation
→
up-regulates activity 		PTPN11SIGNOR-250260
EGFRphosphorylation
→
up-regulates activity 		PTPN11SIGNOR-279460