Entity Details

Name PTPN11_Thr73
ID Q06124
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKACAPTPN11Thr73YGGEKFAtLAELVQYphosphorylation
down-regulates activity		25802336SIGNOR-276891
PKAPTPN11Thr73YGGEKFAtLAELVQYphosphorylation
down-regulates activity		25802336SIGNOR-276893
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKACAphosphorylation
up-regulates
→
PTPN11
PThr73		phosphorylation
down-regulates
⊣		PTPN1125802336SIGNOR-276891
PKAphosphorylation
up-regulates
→
PTPN11
PThr73		phosphorylation
down-regulates
⊣		PTPN1125802336SIGNOR-276893
Regulator Mechanism/Effect Target SIGNOR-ID
PRKACAphosphorylation
→
down-regulates activity 		PTPN11SIGNOR-276891
PKAphosphorylation
→
down-regulates activity 		PTPN11SIGNOR-276893