Entity Details

Name DYRK1A_Ser159
ID Q07820
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
DYRK1AMCL1Ser159NNTSTDGsLPSTPPPphosphorylation
up-regulates quantity		32587776SIGNOR-279704
GSK3BMCL1Ser159NNTSTDGsLPSTPPPphosphorylation
down-regulates quantity by destabilization		16543145SIGNOR-251242
GSK3BMCL1Ser159NNTSTDGsLPSTPPPphosphorylation
down-regulates		16543145SIGNOR-145200
GSK3AMCL1Ser159NNTSTDGsLPSTPPPphosphorylation
down-regulates quantity by destabilization		16543145SIGNOR-251217
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
DYRK1Aphosphorylation
up-regulates
→
MCL1
PSer159		phosphorylation
up-regulates
→		MCL132587776SIGNOR-279704
GSK3Bphosphorylation
up-regulates
→
MCL1
PSer159		phosphorylation
down-regulates
⊣		MCL116543145SIGNOR-251242
GSK3Bphosphorylation
up-regulates
→
MCL1
PSer159		phosphorylation
down-regulates
⊣		MCL116543145SIGNOR-145200
GSK3Aphosphorylation
up-regulates
→
MCL1
PSer159		phosphorylation
down-regulates
⊣		MCL116543145SIGNOR-251217
Regulator Mechanism/Effect Target SIGNOR-ID
DYRK1Aphosphorylation
→
up-regulates quantity 		MCL1SIGNOR-279704
GSK3Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MCL1SIGNOR-251242
GSK3Bphosphorylation
img/direct_inhibition.png
down-regulates 		MCL1SIGNOR-145200
GSK3Aphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MCL1SIGNOR-251217