| Name | SREBF2 |
| ID | Q12772 |
| Role | substrate |
| Enzymatic Domains |
bHLH 330-380 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | SREBF2 | Ser432 | NQNVLLMsPPASDSG | phosphorylation up-regulates | 14988395 | SIGNOR-123041 |
| MAPK3 | SREBF2 | Ser455 | SIDSEPGsPLLDDAK | phosphorylation up-regulates | 14988395 | SIGNOR-123053 |
| ERK1/2 | SREBF2 | – | phosphorylation up-regulates | 14988395 | SIGNOR-270141 | |
| Gbeta | SREBF2 | – | phosphorylation up-regulates | 14988395 | SIGNOR-270012 | |
| MAPK1 | SREBF2 | Ser455 | SIDSEPGsPLLDDAK | phosphorylation up-regulates | 14988395 | SIGNOR-123045 |
| MAPK3 | SREBF2 | Ser432 | NQNVLLMsPPASDSG | phosphorylation up-regulates | 14988395 | SIGNOR-123049 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | SREBF2 PSer432 | phosphorylation up-regulates → | SREBF2 | 14988395 | SIGNOR-123041 |
| MAPK3 | phosphorylation up-regulates → | SREBF2 PSer455 | phosphorylation up-regulates → | SREBF2 | 14988395 | SIGNOR-123053 |
| MAPK1 | phosphorylation up-regulates → | SREBF2 PSer455 | phosphorylation up-regulates → | SREBF2 | 14988395 | SIGNOR-123045 |
| MAPK3 | phosphorylation up-regulates → | SREBF2 PSer432 | phosphorylation up-regulates → | SREBF2 | 14988395 | SIGNOR-123049 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation → up-regulates | SREBF2 | SIGNOR-123041 |
| MAPK3 | phosphorylation → up-regulates | SREBF2 | SIGNOR-123053 |
| ERK1/2 | phosphorylation → up-regulates | SREBF2 | SIGNOR-270141 |
| Gbeta | phosphorylation → up-regulates | SREBF2 | SIGNOR-270012 |
| MAPK1 | phosphorylation → up-regulates | SREBF2 | SIGNOR-123045 |
| MAPK3 | phosphorylation → up-regulates | SREBF2 | SIGNOR-123049 |