Entity Details

Name AKT1_Thr24
ID Q12778
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1FOXO1Thr24LPRPRSCtWPLPRPEphosphorylation
down-regulates activity		10377430SIGNOR-236163
AKTFOXO1Thr24LPRPRSCtWPLPRPEphosphorylation
down-regulates activity		10377430SIGNOR-252347
AKT2FOXO1Thr24LPRPRSCtWPLPRPEphosphorylation
down-regulates activity		10377430SIGNOR-68656
SGK1FOXO1Thr24LPRPRSCtWPLPRPEphosphorylation
down-regulates activity		19965929SIGNOR-255925
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
FOXO1
PThr24		phosphorylation
down-regulates
⊣		FOXO110377430SIGNOR-236163
AKTphosphorylation
up-regulates
→
FOXO1
PThr24		phosphorylation
down-regulates
⊣		FOXO110377430SIGNOR-252347
AKT2phosphorylation
up-regulates
→
FOXO1
PThr24		phosphorylation
down-regulates
⊣		FOXO110377430SIGNOR-68656
SGK1phosphorylation
up-regulates
→
FOXO1
PThr24		phosphorylation
down-regulates
⊣		FOXO119965929SIGNOR-255925
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
→
down-regulates activity 		FOXO1SIGNOR-236163
AKTphosphorylation
→
down-regulates activity 		FOXO1SIGNOR-252347
AKT2phosphorylation
→
down-regulates activity 		FOXO1SIGNOR-68656
SGK1phosphorylation
→
down-regulates activity 		FOXO1SIGNOR-255925