Entity Details

Name CDK2_Ser249
ID Q12778
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1FOXO1Ser249EGGKSGKsPRRRAASphosphorylation
down-regulates		18408765SIGNOR-178202
CDK2FOXO1Ser249EGGKSGKsPRRRAASphosphorylation
down-regulates		17038621SIGNOR-150028
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
FOXO1
PSer249		phosphorylation
down-regulates
⊣		FOXO118408765SIGNOR-178202
CDK2phosphorylation
up-regulates
→
FOXO1
PSer249		phosphorylation
down-regulates
⊣		FOXO117038621SIGNOR-150028
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
img/direct_inhibition.png
down-regulates 		FOXO1SIGNOR-178202
CDK2phosphorylation
img/direct_inhibition.png
down-regulates 		FOXO1SIGNOR-150028