Entity Details

Name PRKG2_Ser319
ID Q12778
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKTFOXO1Ser319TFRPRTSsNASTISGphosphorylation
down-regulates activity		11237865SIGNOR-252349
PRKG2FOXO1Ser319TFRPRTSsNASTISGphosphorylation
up-regulates activity		22393355SIGNOR-279564
AKT1FOXO1Ser319TFRPRTSsNASTISGphosphorylation
down-regulates		11237865SIGNOR-105459
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKTphosphorylation
up-regulates
→
FOXO1
PSer319		phosphorylation
down-regulates
⊣		FOXO111237865SIGNOR-252349
PRKG2phosphorylation
up-regulates
→
FOXO1
PSer319		phosphorylation
up-regulates
→		FOXO122393355SIGNOR-279564
AKT1phosphorylation
up-regulates
→
FOXO1
PSer319		phosphorylation
down-regulates
⊣		FOXO111237865SIGNOR-105459
Regulator Mechanism/Effect Target SIGNOR-ID
AKTphosphorylation
→
down-regulates activity 		FOXO1SIGNOR-252349
PRKG2phosphorylation
→
up-regulates activity 		FOXO1SIGNOR-279564
AKT1phosphorylation
img/direct_inhibition.png
down-regulates 		FOXO1SIGNOR-105459