| Name | PTPRJ |
| ID | Q12913 |
| Role | substrate |
| Enzymatic Domains |
Fibronectin type-III 1 121-209 PROSITE-ProRule
Fibronectin type-III 2 207-291 PROSITE-ProRule
Fibronectin type-III 3 271-364 PROSITE-ProRule
Fibronectin type-III 4 368-456 PROSITE-ProRule
Fibronectin type-III 5 457-541 PROSITE-ProRule
Fibronectin type-III 6 542-623 PROSITE-ProRule
Fibronectin type-III 7 625-720 PROSITE-ProRule
Fibronectin type-III 8 721-817 PROSITE-ProRule
Fibronectin type-III 9 816-902 PROSITE-ProRule
Tyrosine-protein phosphatase 1041-1298 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | PTPRJ | Tyr1311 | DSKVDLIyQNTTAMT | phosphorylation up-regulates activity | 22898603 | SIGNOR-276373 |
| CSNK2A1 | PTPRJ | Thr1318 | YQNTTAMtIYENLAP | phosphorylation up-regulates activity | 24583284 | SIGNOR-277876 |
| FYN | PTPRJ | Tyr1311 | DSKVDLIyQNTTAMT | phosphorylation up-regulates activity | 22898603 | SIGNOR-276372 |
| FYN | PTPRJ | Tyr1320 | NTTAMTIyENLAPVT | phosphorylation up-regulates activity | 22898603 | SIGNOR-276374 |
| SRC | PTPRJ | Tyr1320 | NTTAMTIyENLAPVT | phosphorylation up-regulates activity | 22898603 | SIGNOR-276375 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | PTPRJ PTyr1311 | phosphorylation up-regulates → | PTPRJ | 22898603 | SIGNOR-276373 |
| CSNK2A1 | phosphorylation up-regulates → | PTPRJ PThr1318 | phosphorylation up-regulates → | PTPRJ | 24583284 | SIGNOR-277876 |
| FYN | phosphorylation up-regulates → | PTPRJ PTyr1311 | phosphorylation up-regulates → | PTPRJ | 22898603 | SIGNOR-276372 |
| FYN | phosphorylation up-regulates → | PTPRJ PTyr1320 | phosphorylation up-regulates → | PTPRJ | 22898603 | SIGNOR-276374 |
| SRC | phosphorylation up-regulates → | PTPRJ PTyr1320 | phosphorylation up-regulates → | PTPRJ | 22898603 | SIGNOR-276375 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → up-regulates activity | PTPRJ | SIGNOR-276373 |
| CSNK2A1 | phosphorylation → up-regulates activity | PTPRJ | SIGNOR-277876 |
| FYN | phosphorylation → up-regulates activity | PTPRJ | SIGNOR-276372 |
| FYN | phosphorylation → up-regulates activity | PTPRJ | SIGNOR-276374 |
| SRC | phosphorylation → up-regulates activity | PTPRJ | SIGNOR-276375 |