| Name | TRAF2 |
| ID | Q12933 |
| Role | substrate |
| Enzymatic Domains |
MATH 351-496 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | TRAF2 | Thr117 | DGCTWKGtLKEYESC | dephosphorylation down-regulates activity | 17188031 | SIGNOR-248640 |
| PPP2CB | TRAF2 | Thr117 | DGCTWKGtLKEYESC | dephosphorylation down-regulates activity | 17188031 | SIGNOR-248597 |
| IKBKE | TRAF2 | Ser11 | ASVTPPGsLELLQPG | phosphorylation up-regulates activity | 24362534 | SIGNOR-279195 |
| MAP4K4 | TRAF2 | Ser35 | LEAKYLCsACRNVLR | phosphorylation down-regulates quantity | 25098764 | SIGNOR-279536 |
| PRKCZ | TRAF2 | Ser55 | QCGHRYCsFCLASIL | phosphorylation unknown | 19336568 | SIGNOR-184941 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | dephosphorylation down-regulates ⊣ | TRAF2 PThr117 | dephosphorylation up-regulates → | TRAF2 | 17188031 | SIGNOR-248640 |
| PPP2CB | dephosphorylation down-regulates ⊣ | TRAF2 PThr117 | dephosphorylation up-regulates → | TRAF2 | 17188031 | SIGNOR-248597 |
| IKBKE | phosphorylation up-regulates → | TRAF2 PSer11 | phosphorylation up-regulates → | TRAF2 | 24362534 | SIGNOR-279195 |
| MAP4K4 | phosphorylation up-regulates → | TRAF2 PSer35 | phosphorylation down-regulates ⊣ | TRAF2 | 25098764 | SIGNOR-279536 |
| PRKCZ | phosphorylation up-regulates → | TRAF2 PSer55 | phosphorylation down-regulates ⊣ | TRAF2 | 19336568 | SIGNOR-184941 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2CA | dephosphorylation → down-regulates activity | TRAF2 | SIGNOR-248640 |
| PPP2CB | dephosphorylation → down-regulates activity | TRAF2 | SIGNOR-248597 |
| IKBKE | phosphorylation → up-regulates activity | TRAF2 | SIGNOR-279195 |
| MAP4K4 | phosphorylation → down-regulates quantity | TRAF2 | SIGNOR-279536 |
| PRKCZ | phosphorylation → unknown | TRAF2 | SIGNOR-184941 |