Entity Details

Name TRAF2
ID Q12933
Role substrate
Enzymatic Domains
MATH 351-496
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPP2CATRAF2Thr117DGCTWKGtLKEYESCdephosphorylation
down-regulates activity
17188031SIGNOR-248640
PPP2CBTRAF2Thr117DGCTWKGtLKEYESCdephosphorylation
down-regulates activity
17188031SIGNOR-248597
IKBKETRAF2Ser11 ASVTPPGsLELLQPGphosphorylation
up-regulates activity
24362534SIGNOR-279195
MAP4K4TRAF2Ser35LEAKYLCsACRNVLRphosphorylation
down-regulates quantity
25098764SIGNOR-279536
PRKCZTRAF2Ser55QCGHRYCsFCLASILphosphorylation
unknown
19336568SIGNOR-184941
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPP2CAdephosphorylation
down-regulates
TRAF2
PThr117
dephosphorylation
up-regulates
TRAF217188031SIGNOR-248640
PPP2CBdephosphorylation
down-regulates
TRAF2
PThr117
dephosphorylation
up-regulates
TRAF217188031SIGNOR-248597
IKBKEphosphorylation
up-regulates
TRAF2
PSer11
phosphorylation
up-regulates
TRAF224362534SIGNOR-279195
MAP4K4phosphorylation
up-regulates
TRAF2
PSer35
phosphorylation
down-regulates
TRAF225098764SIGNOR-279536
PRKCZphosphorylation
up-regulates
TRAF2
PSer55
phosphorylation
down-regulates
TRAF219336568SIGNOR-184941
Regulator Mechanism/Effect Target SIGNOR-ID
PPP2CAdephosphorylation

down-regulates activity
TRAF2SIGNOR-248640
PPP2CBdephosphorylation

down-regulates activity
TRAF2SIGNOR-248597
IKBKEphosphorylation

up-regulates activity
TRAF2SIGNOR-279195
MAP4K4phosphorylation

down-regulates quantity
TRAF2SIGNOR-279536
PRKCZphosphorylation

unknown
TRAF2SIGNOR-184941