| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | TRAF2 | Thr117 | DGCTWKGtLKEYESC | dephosphorylation down-regulates activity | 17188031 | SIGNOR-248640 |
| PPP2CB | TRAF2 | Thr117 | DGCTWKGtLKEYESC | dephosphorylation down-regulates activity | 17188031 | SIGNOR-248597 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | dephosphorylation down-regulates ⊣ | TRAF2 PThr117 | dephosphorylation up-regulates → | TRAF2 | 17188031 | SIGNOR-248640 |
| PPP2CB | dephosphorylation down-regulates ⊣ | TRAF2 PThr117 | dephosphorylation up-regulates → | TRAF2 | 17188031 | SIGNOR-248597 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2CA | dephosphorylation → down-regulates activity | TRAF2 | SIGNOR-248640 |
| PPP2CB | dephosphorylation → down-regulates activity | TRAF2 | SIGNOR-248597 |