| Name | DLG1 |
| ID | Q12959 |
| Role | substrate |
| Enzymatic Domains |
L27 4-64 PROSITE-ProRule
PDZ 1 224-310 PROSITE-ProRule
PDZ 2 319-405 PROSITE-ProRule
PDZ 3 466-546 PROSITE-ProRule
SH3 581-651 PROSITE-ProRule
Guanylate kinase-like 714-889 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | DLG1 | Ser443 | FLGQTPAsPARYSPV | phosphorylation up-regulates | 19066288 | SIGNOR-182765 |
| CDK1 | DLG1 | Ser443 | FLGQTPAsPARYSPV | phosphorylation unknown | 19066288 | SIGNOR-182757 |
| CAMK2A | DLG1 | Ser232 | ITLERGNsGLGFSIA | phosphorylation down-regulates activity | 12933808 | SIGNOR-250618 |
| CDK2 | DLG1 | Ser158 | FVSHSHIsPIKPTEA | phosphorylation up-regulates | 19066288 | SIGNOR-182761 |
| CDK1 | DLG1 | Ser158 | FVSHSHIsPIKPTEA | phosphorylation unknown | 19066288 | SIGNOR-182753 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | DLG1 PSer443 | phosphorylation up-regulates → | DLG1 | 19066288 | SIGNOR-182765 |
| CDK1 | phosphorylation up-regulates → | DLG1 PSer443 | phosphorylation down-regulates ⊣ | DLG1 | 19066288 | SIGNOR-182757 |
| CAMK2A | phosphorylation up-regulates → | DLG1 PSer232 | phosphorylation down-regulates ⊣ | DLG1 | 12933808 | SIGNOR-250618 |
| CDK2 | phosphorylation up-regulates → | DLG1 PSer158 | phosphorylation up-regulates → | DLG1 | 19066288 | SIGNOR-182761 |
| CDK1 | phosphorylation up-regulates → | DLG1 PSer158 | phosphorylation down-regulates ⊣ | DLG1 | 19066288 | SIGNOR-182753 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation → up-regulates | DLG1 | SIGNOR-182765 |
| CDK1 | phosphorylation → unknown | DLG1 | SIGNOR-182757 |
| CAMK2A | phosphorylation → down-regulates activity | DLG1 | SIGNOR-250618 |
| CDK2 | phosphorylation → up-regulates | DLG1 | SIGNOR-182761 |
| CDK1 | phosphorylation → unknown | DLG1 | SIGNOR-182753 |