| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RAF1 | KLF10 | Thr93 | TIPAFCLtPPYSPSD | phosphorylation down-regulates quantity by destabilization | 23994618 | SIGNOR-276502 |
| TYK2 | KLF10 | – | phosphorylation down-regulates activity | 21471442 | SIGNOR-279575 | |
| CDK2 | KLF10 | Ser206 | NIPCAAVsPNRSKCE | phosphorylation up-regulates quantity | 25728284 | SIGNOR-278394 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RAF1 | phosphorylation up-regulates → | KLF10 PThr93 | phosphorylation down-regulates ⊣ | KLF10 | 23994618 | SIGNOR-276502 |
| CDK2 | phosphorylation up-regulates → | KLF10 PSer206 | phosphorylation up-regulates → | KLF10 | 25728284 | SIGNOR-278394 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RAF1 | phosphorylation![]() down-regulates quantity by destabilization | KLF10 | SIGNOR-276502 |
| TYK2 | phosphorylation → down-regulates activity | KLF10 | SIGNOR-279575 |
| CDK2 | phosphorylation → up-regulates quantity | KLF10 | SIGNOR-278394 |