| Name | PRKAA1 |
| ID | Q13131 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 27-279 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKAA1 | CFTR | Ser737 | EPLERRLsLVPDSEQ | phosphorylation down-regulates activity | 19095655 | SIGNOR-259858 |
| PRKAA1 | EP300 | Ser89 | SELLRSGsSPNLNMG | phosphorylation down-regulates | 21940946 | SIGNOR-176637 |
| PRKAA1 | PRKAB1 | Ser108 | SKLPLTRsHNNFVAI | phosphorylation up-regulates | 17728241 | SIGNOR-157553 |
| PRKAA1 | SNAI1 | Ser92 | SFLVRKPsDPNRKPN | phosphorylation up-regulates quantity by stabilization | 19923321 | SIGNOR-161779 |
| PRKAA1 | FOXO3 | Ser626 | SLECDMEsIIRSELM | phosphorylation up-regulates activity | 17711846 | SIGNOR-249687 |
| PRKAA1 | HDAC4 | – | phosphorylation down-regulates | 21565617 | SIGNOR-173689 | |
| PRKAA1 | USP10 | Ser76 | DTLPRTPsYSISSTL | phosphorylation up-regulates activity | 26876938 | SIGNOR-277207 |
| PRKAA1 | RRN3 | Ser635 | DTHFRSPsSSVGSPP | phosphorylation down-regulates | 19815529 | SIGNOR-188403 |
| PRKAA1 | SREBF1 | – | phosphorylation down-regulates activity | 21892142 | SIGNOR-176497 | |
| PRKAA1 | CRTC2 | Ser170 | PSALNRTsSDSALHT | phosphorylation down-regulates | 21892142 | SIGNOR-176426 |
| PRKAA1 | SIRT1 | – | phosphorylation down-regulates activity | 26363315 | SIGNOR-280076 | |
| PRKAA1 | KPNA2 | Ser105 | QAARKLLsREKQPPI | phosphorylation up-regulates | 15342649 | SIGNOR-128629 |
| PRKAA1 | KLC2 | Ser582 | PRMKRASsLNFLNKS | phosphorylation up-regulates | 21725060 | SIGNOR-174681 |
| PRKAA1 | KCNA5 | Ser559 | VQRKVSGsRGSFCKA | phosphorylation down-regulates activity | 30279167 | SIGNOR-277799 |
| PRKAA1 | PFKFB2 | Ser466 | PVRMRRNsFTPLSSSN | phosphorylation up-regulates activity | 11069105 | SIGNOR-260012 |
| PRKAA1 | RAF1 | Ser621 | PKINRSAsEPSLHRA | phosphorylation down-regulates | 9091312 | SIGNOR-47148 |
| PRKAA1 | FOXO | – | phosphorylation up-regulates activity | 17900900 | SIGNOR-252983 | |
| PRKAA1 | MFF | Ser155 | GRLKRERsMSENAVR | phosphorylation up-regulates activity | 26816379 | SIGNOR-245953 |
| PRKAA1 | NR2C2 | Ser351 | HVISRDQsTPIIEVE | phosphorylation down-regulates | 21478464 | SIGNOR-173118 |
| PRKAA1 | NFE2L2 | Ser374 | GDTLLGLsDSEVEEL | phosphorylation up-regulates activity | 31805502 | SIGNOR-277494 |
| PRKAA1 | PFKFB2 | Ser466 | PVRMRRNsFTPLSSS | phosphorylation up-regulates activity | 11069105 | SIGNOR-84061 |
| PRKAA1 | ACSS2 | Ser659 | PGLPKTRsGKIMRRV | phosphorylation up-regulates activity | 28820290 | SIGNOR-271822 |
| PRKAA1 | DDIT3 | Ser30 | EDLQEVLsSDENGGT | phosphorylation down-regulates quantity | 27650555 | SIGNOR-278381 |
| PRKAA1 | HIPK2 | Ser121 | LMRRSTVsLLDTYQK | phosphorylation up-regulates activity | 23871434 | SIGNOR-276467 |
| PRKAA1 | EGLN1 | Ser136 | AAAGGQGsAVAAEAE | phosphorylation down-regulates activity | 35538889 | SIGNOR-277593 |
| PRKAA1 | HIPK2 | Thr119 | HNLMRRStVSLLDTY | phosphorylation up-regulates activity | 23871434 | SIGNOR-276468 |
| PRKAA1 | NFE2L2 | Ser433 | PEKELPVsPGHRKTP | phosphorylation up-regulates activity | 31805502 | SIGNOR-277495 |
| PRKAA1 | NFE2L2 | Ser408 | GDMVQPLsPSQGQST | phosphorylation up-regulates activity | 31805502 | SIGNOR-277496 |
| PRKAA1 | CRY1 | Ser71 | ANLRKLNsRLFVIRG | phosphorylation down-regulates | 21892142 | SIGNOR-176472 |
| PRKAA1 | POU2F1 | Ser385 | RRRKKRTsIETNIRV | phosphorylation down-regulates | 9368058 | SIGNOR-53254 |
| PRKAA1 | ULK1 | – | phosphorylation up-regulates activity | 21460634 | SIGNOR-173038 | |
| PRKAA1 | ZNF692 | Ser470 | VAAHRSKsHPALLLA | phosphorylation down-regulates | 17097062 | SIGNOR-150590 |
| PRKAA1 | TSC2 | – | phosphorylation up-regulates activity | 31235817 | SIGNOR-278981 | |
| PRKAA1 | HAT1 | Ser190 | MWFIETAsFIDVDDE | phosphorylation up-regulates activity | 28143904 | SIGNOR-264782 |
| PRKAA1 | CTBP1 | Ser158 | REGTRVQsVEQIREV | phosphorylation down-regulates | 23291169 | SIGNOR-200250 |
| PRKAA1 | HDAC7 | Ser155 | FPLRKTVsEPNLKLR | phosphorylation down-regulates | 21892142 | SIGNOR-176487 |
| PRKAA1 | ACACA | Ser1201 | IPTLNRMsFSSNLNH | phosphorylation down-regulates activity | 7907095 | SIGNOR-250400 |
| PRKAA1 | HDAC5 | Ser259 | FPLRKTAsEPNLKVR | phosphorylation down-regulates | 21892142 | SIGNOR-176479 |
| PRKAA1 | HNF4A | Ser303 | DPDAKGLsDPGKIKR | phosphorylation down-regulates activity | 12740371 | SIGNOR-101101 |
| PRKAA1 | FOXO | Ser588 | QTLSDSLsGSSLYST | phosphorylation up-regulates activity | 17711846 | SIGNOR-252978 |
| PRKAA1 | EGLN1 | Ser61 | HKLVCQGsEGALGHG | phosphorylation down-regulates activity | 35538889 | SIGNOR-277592 |
| PRKAA1 | KIF4A | Ser801 | KLRRRTFsLTEVRGQ | phosphorylation up-regulates activity | 28992084 | SIGNOR-265991 |
| PRKAA1 | INSIG1 | Thr222 | ITIAFLAtLITQFLV | phosphorylation up-regulates quantity by stabilization | 30733434 | SIGNOR-277430 |
| PRKAA1 | BTRC | Ser82 | SLRQTYNsCARLCLN | phosphorylation down-regulates quantity by destabilization | 31406304 | SIGNOR-277475 |
| PRKAA1 | FOXO | Ser626 | SLECDMEsIIRSELM | phosphorylation up-regulates activity | 17711846 | SIGNOR-252979 |
| PRKAA1 | EEF2K | Ser78 | SSGSPANsFHFKEAW | phosphorylation down-regulates activity | 14709557 | SIGNOR-250314 |
| PRKAA1 | GLI1 | Ser408 | GPLPRAPsISTVEPK | phosphorylation down-regulates activity | 26190112 | SIGNOR-259863 |
| PRKAA1 | KCNA5 | Ser592 | KCNVKAKsNVDLRRS | phosphorylation down-regulates activity | 30279167 | SIGNOR-277814 |
| PRKAA1 | FOXO | – | phosphorylation up-regulates | 17900900 | SIGNOR-252981 | |
| PRKAA1 | GLI1 | Thr1074 | QRGSSGHtPPPSGPP | phosphorylation down-regulates activity | 26190112 | SIGNOR-259862 |
| PRKAA1 | MAPT | Ser214 | GGKERPGsKEEVDED | phosphorylation down-regulates activity | 10090741 | SIGNOR-275439 |
| PRKAA1 | NOS3 | Ser1177 | TSRIRTQsFSLQERQ | phosphorylation up-regulates | 18303014 | SIGNOR-160838 |
| PRKAA1 | GLI1 | Ser102 | LQTVIRTsPSSLVAF | phosphorylation down-regulates activity | 26190112 | SIGNOR-259861 |
| PRKAA1 | HIPK2 | Thr1114 | APAALGStGTVAHLV | phosphorylation up-regulates activity | 23871434 | SIGNOR-276469 |
| PRKAA1 | RBBP7 | Ser314 | LKLHTFEsHKDEIFQ | phosphorylation up-regulates activity | 28143904 | SIGNOR-264784 |
| PRKAA1 | DDIT3 | Ser30 | EDLQEVLsSDENGGT | phosphorylation down-regulates activity | 27650555 | SIGNOR-259864 |
| PRKAA1 | CFTR | Ser768 | LQARRRQsVLNLMTH | phosphorylation down-regulates activity | 19095655 | SIGNOR-259867 |
| PRKAA1 | NOS3 | Thr495 | TGITRKKtFKEVANA | phosphorylation up-regulates activity | 24379783 | SIGNOR-251619 |
| PRKAA1 | KCNA5 | Ser559 | VQRKVSGsRGSFCKA | phosphorylation down-regulates activity | 30279167 | SIGNOR-277813 |
| PRKAA1 | PPARGC1A | Ser539 | SLFNVSPsCSSFNSP | phosphorylation up-regulates activity | 17609368 | SIGNOR-228654 |
| PRKAA1 | FOXO3 | – | phosphorylation up-regulates activity | 22848740 | SIGNOR-255755 | |
| PRKAA1 | FOXO3 | Ser399 | DNITLPPsQPSPTGG | phosphorylation up-regulates activity | 17711846 | SIGNOR-249667 |
| PRKAA1 | PIAS1 | Ser510 | SPVSRTPsLPAVDTS | phosphorylation up-regulates activity | 27256105 | SIGNOR-259866 |
| PRKAA1 | MAPT | Ser267 | RVQSKIGsLDNITHV | phosphorylation down-regulates activity | 10090741 | SIGNOR-275438 |
| PRKAA1 | PRPS2 | Ser180 | GGAKRVTsIADRLNV | phosphorylation down-regulates activity | 29074724 | SIGNOR-265731 |
| PRKAA1 | TBC1D1 | Ser237 | RPMRKSFsQPGLRSL | phosphorylation down-regulates | 17995453 | SIGNOR-159048 |
| PRKAA1 | FOXO | Ser399 | DNITLPPsQPSPTGG | phosphorylation up-regulates activity | 17711846 | SIGNOR-252975 |
| PRKAA1 | GAPDH | Ser122 | GAKRVIIsAPSADAP | phosphorylation up-regulates activity | 26626483 | SIGNOR-259857 |
| PRKAA1 | HDAC5 | Ser498 | RPLSRTQsSPLPQSP | phosphorylation down-regulates | 21892142 | SIGNOR-176483 |
| PRKAA1 | MLXIPL | – | phosphorylation down-regulates | 11724780 | SIGNOR-112289 | |
| PRKAA1 | GFPT1 | Ser242 | SKFTRWGsQGERGKD | phosphorylation down-regulates | 19170765 | SIGNOR-183528 |
| PRKAA1 | RPTOR | Ser792 | DKMRRASsYSSLNSL | phosphorylation down-regulates activity | 18439900 | SIGNOR-161375 |
| PRKAA1 | STIM1 | Ser257 | GLHRAEQsLHDLQER | phosphorylation down-regulates activity | 31381180 | SIGNOR-277299 |
| PRKAA1 | EEF2K | Ser366 | SPQVRTLsGSRPPLL | phosphorylation down-regulates activity | 14709557 | SIGNOR-250402 |
| PRKAA1 | POU2F1 | Ser385 | RRRKKRTsIETNIRV | phosphorylation down-regulates | 1684878 | SIGNOR-20971 |
| PRKAA1 | PDHA1 | Ser295 | RYHGHSMsDPGVSYR | phosphorylation up-regulates activity | 33022274 | SIGNOR-276837 |
| PRKAA1 | MAPT | Ser355 | EADLPEPsEKQPAAA | phosphorylation down-regulates activity | 10090741 | SIGNOR-275440 |
| PRKAA1 | MLXIPL | – | phosphorylation down-regulates | 21892142 | SIGNOR-176494 | |
| PRKAA1 | MFF | Ser172 | GQLVRNDsLWHRSDS | phosphorylation up-regulates activity | 26816379 | SIGNOR-249656 |
| PRKAA1 | MCU | Ser57 | TVHQRIAsWQNLGAV | phosphorylation up-regulates activity | 30858581 | SIGNOR-275547 |
| PRKAA1 | LIPE | Ser855 | EPMRRSVsEAALAQP | phosphorylation down-regulates | 9636039 | SIGNOR-58255 |
| PRKAA1 | CDKN1B | Thr198 | PGLRRRQt | phosphorylation up-regulates quantity by stabilization | 30033086 | SIGNOR-259859 |
| PRKAA1 | CRTC1 | – | phosphorylation down-regulates | 21331044 | SIGNOR-172136 | |
| PRKAA1 | KCNA5 | Ser592 | KCNVKAKsNVDLRRS | phosphorylation down-regulates activity | 30279167 | SIGNOR-277800 |
| PRKAA1 | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates | 15866171 | SIGNOR-135960 |
| PRKAA1 | GSR | Thr507 | TKADFDNtVAIHPTS | phosphorylation up-regulates activity | 31530934 | SIGNOR-273734 |
| PRKAA1 | CCNY | Ser326 | SARKRSAsADNLTLP | phosphorylation up-regulates activity | 32723157 | SIGNOR-273011 |
| PRKAA1 | RPTOR | – | phosphorylation down-regulates activity | 21460634 | SIGNOR-173035 | |
| PRKAA1 | FOXO3 | Ser588 | QTLSDSLsGSSLYST | phosphorylation up-regulates activity | 17711846 | SIGNOR-249684 |
| PRKAA1 | FOXO3 | Thr179 | SSPDKRLtLSQIYEW | phosphorylation up-regulates activity | 17711846 | SIGNOR-238804 |
| PRKAA1 | GBF1 | Thr1337 | GKIHRSAtDADVVNS | phosphorylation down-regulates | 18063581 | SIGNOR-159639 |
| PRKAA1 | PPARGC1A | Thr178 | NHNHRIRtNPAIVKT | phosphorylation up-regulates activity | 17609368 | SIGNOR-156780 |
| PRKAA1 | FOXO4 | – | phosphorylation up-regulates | 17900900 | SIGNOR-157947 | |
| PRKAA1 | SNAI1 | Ser92 | VAELTSLsDEDSGKG | phosphorylation up-regulates | 19923321 | SIGNOR-161783 |
| PRKAA1 | SYN1 | Ser9 | NYLRRRLsDSNFMAN | phosphorylation down-regulates activity | 10880969 | SIGNOR-78891 |
| PRKAA1 | PRKAA1 | Ser486 | DDEITEAKsGTATPQRS | phosphorylation down-regulates activity | 17023420 | SIGNOR-256114 |
| PRKAA1 | HDAC7 | Ser358 | WPLSRTRsEPLPPSA | phosphorylation down-regulates | 21892142 | SIGNOR-176491 |
| PRKAA1 | FOXO | Ser555 | RALSNSVsNMGLSES | phosphorylation up-regulates activity | 17711846 | SIGNOR-252977 |
| PRKAA1 | FANCA | Ser347 | VQMQREWsFARTHPL | phosphorylation up-regulates activity | 27449087 | SIGNOR-277264 |
| PRKAA1 | TET2 | Ser99 | GGIKRTVsEPSLSGLL | phosphorylation up-regulates quantity by stabilization | 30022161 | SIGNOR-256134 |
| PRKAA1 | GFPT1 | Ser261 | CNLSRVDsTTCLFPV | phosphorylation up-regulates | 17941647 | SIGNOR-158490 |
| PRKAA1 | PFKFB3 | Ser461 | NPLMRRNsVTPLASP | phosphorylation up-regulates | 12065600 | SIGNOR-89760 |
| PRKAA1 | SIRT7 | Thr153 | TLTHMSItRLHEQKL | phosphorylation down-regulates quantity by destabilization | 27511885 | SIGNOR-275864 |
| PRKAA1 | DNMT1 | Ser714 | DNIPEMPsPKKMHQG | phosphorylation down-regulates activity | 28143904 | SIGNOR-264783 |
| PRKAA1 | RB1 | Ser811 | IYISPLKsPYKISEG | phosphorylation down-regulates | 19217427 | SIGNOR-184052 |
| PRKAA1 | RAF1 | Ser259 | SQRQRSTsTPNVHMV | phosphorylation down-regulates | 11971957 | SIGNOR-86133 |
| PRKAA1 | EEF2K | Ser398 | DSLPSSPsSATPHSQ | phosphorylation up-regulates activity | 14709557 | SIGNOR-250157 |
| PRKAA1 | FOXO | Thr179 | SSPDKRLtLSQIYEW | phosphorylation up-regulates activity | 17711846 | SIGNOR-252980 |
| PRKAA1 | FOXO | Ser413 | GLMQRSSsFPYTTKG | phosphorylation up-regulates activity | 17711846 | SIGNOR-252976 |
| PRKAA1 | SCN5A | Thr101 | IVLNKGKtIFRFSAT | phosphorylation down-regulates quantity by destabilization | 30759345 | SIGNOR-277432 |
| PRKAA1 | FOXO3 | Ser555 | RALSNSVsNMGLSES | phosphorylation up-regulates activity | 17711846 | SIGNOR-249681 |
| PRKAA1 | FOXO3 | Ser413 | GLMQRSSsFPYTTKG | phosphorylation up-regulates activity | 17711846 | SIGNOR-249677 |
| PRKAA1 | GLI1 | Ser408 | GPLPRAPsISTVEPK | phosphorylation down-regulates activity | 26190112 | SIGNOR-259860 |
| PRKAA1 | FOXO3 | – | phosphorylation up-regulates activity | 17900900 | SIGNOR-219247 | |
| PRKAA1 | PDHA1 | Ser314 | IQEVRSKsDPIMLLK | phosphorylation up-regulates activity | 33022274 | SIGNOR-276839 |
| PRKAA1 | PRPS1 | Ser180 | GGAKRVTsIADRLNV | phosphorylation down-regulates activity | 29074724 | SIGNOR-265729 |
| PRKAA1 | EEF2K | Ser398 | DSLPSSPsSATPHSQ | phosphorylation up-regulates | 22669845 | SIGNOR-197734 |
| PRKAA1 | FOXO1 | – | phosphorylation up-regulates | 17900900 | SIGNOR-157941 | |
| PRKAA1 | ALDH2 | Thr356 | GNPFDSKtEQGPQVD | phosphorylation up-regulates activity | 30375985 | SIGNOR-271863 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKAA1 | phosphorylation up-regulates → | CFTR PSer737 | phosphorylation down-regulates ⊣ | CFTR | 19095655 | SIGNOR-259858 |
| PRKAA1 | phosphorylation up-regulates → | EP300 PSer89 | phosphorylation down-regulates ⊣ | EP300 | 21940946 | SIGNOR-176637 |
| PRKAA1 | phosphorylation up-regulates → | PRKAB1 PSer108 | phosphorylation up-regulates → | PRKAB1 | 17728241 | SIGNOR-157553 |
| PRKAA1 | phosphorylation up-regulates → | SNAI1 PSer92 | phosphorylation up-regulates → | SNAI1 | 19923321 | SIGNOR-161779 |
| PRKAA1 | phosphorylation up-regulates → | FOXO3 PSer626 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-249687 |
| PRKAA1 | phosphorylation up-regulates → | USP10 PSer76 | phosphorylation up-regulates → | USP10 | 26876938 | SIGNOR-277207 |
| PRKAA1 | phosphorylation up-regulates → | RRN3 PSer635 | phosphorylation down-regulates ⊣ | RRN3 | 19815529 | SIGNOR-188403 |
| PRKAA1 | phosphorylation up-regulates → | CRTC2 PSer170 | phosphorylation down-regulates ⊣ | CRTC2 | 21892142 | SIGNOR-176426 |
| PRKAA1 | phosphorylation up-regulates → | KPNA2 PSer105 | phosphorylation up-regulates → | KPNA2 | 15342649 | SIGNOR-128629 |
| PRKAA1 | phosphorylation up-regulates → | KLC2 PSer582 | phosphorylation up-regulates → | KLC2 | 21725060 | SIGNOR-174681 |
| PRKAA1 | phosphorylation up-regulates → | KCNA5 PSer559 | phosphorylation down-regulates ⊣ | KCNA5 | 30279167 | SIGNOR-277799 |
| PRKAA1 | phosphorylation up-regulates → | PFKFB2 PSer466 | phosphorylation up-regulates → | PFKFB2 | 11069105 | SIGNOR-260012 |
| PRKAA1 | phosphorylation up-regulates → | RAF1 PSer621 | phosphorylation down-regulates ⊣ | RAF1 | 9091312 | SIGNOR-47148 |
| PRKAA1 | phosphorylation up-regulates → | MFF PSer155 | phosphorylation up-regulates → | MFF | 26816379 | SIGNOR-245953 |
| PRKAA1 | phosphorylation up-regulates → | NR2C2 PSer351 | phosphorylation down-regulates ⊣ | NR2C2 | 21478464 | SIGNOR-173118 |
| PRKAA1 | phosphorylation up-regulates → | NFE2L2 PSer374 | phosphorylation up-regulates → | NFE2L2 | 31805502 | SIGNOR-277494 |
| PRKAA1 | phosphorylation up-regulates → | PFKFB2 PSer466 | phosphorylation up-regulates → | PFKFB2 | 11069105 | SIGNOR-84061 |
| PRKAA1 | phosphorylation up-regulates → | ACSS2 PSer659 | phosphorylation up-regulates → | ACSS2 | 28820290 | SIGNOR-271822 |
| PRKAA1 | phosphorylation up-regulates → | DDIT3 PSer30 | phosphorylation down-regulates ⊣ | DDIT3 | 27650555 | SIGNOR-278381 |
| PRKAA1 | phosphorylation up-regulates → | HIPK2 PSer121 | phosphorylation up-regulates → | HIPK2 | 23871434 | SIGNOR-276467 |
| PRKAA1 | phosphorylation up-regulates → | EGLN1 PSer136 | phosphorylation down-regulates ⊣ | EGLN1 | 35538889 | SIGNOR-277593 |
| PRKAA1 | phosphorylation up-regulates → | HIPK2 PThr119 | phosphorylation up-regulates → | HIPK2 | 23871434 | SIGNOR-276468 |
| PRKAA1 | phosphorylation up-regulates → | NFE2L2 PSer433 | phosphorylation up-regulates → | NFE2L2 | 31805502 | SIGNOR-277495 |
| PRKAA1 | phosphorylation up-regulates → | NFE2L2 PSer408 | phosphorylation up-regulates → | NFE2L2 | 31805502 | SIGNOR-277496 |
| PRKAA1 | phosphorylation up-regulates → | CRY1 PSer71 | phosphorylation down-regulates ⊣ | CRY1 | 21892142 | SIGNOR-176472 |
| PRKAA1 | phosphorylation up-regulates → | POU2F1 PSer385 | phosphorylation down-regulates ⊣ | POU2F1 | 9368058 | SIGNOR-53254 |
| PRKAA1 | phosphorylation up-regulates → | ZNF692 PSer470 | phosphorylation down-regulates ⊣ | ZNF692 | 17097062 | SIGNOR-150590 |
| PRKAA1 | phosphorylation up-regulates → | HAT1 PSer190 | phosphorylation up-regulates → | HAT1 | 28143904 | SIGNOR-264782 |
| PRKAA1 | phosphorylation up-regulates → | CTBP1 PSer158 | phosphorylation down-regulates ⊣ | CTBP1 | 23291169 | SIGNOR-200250 |
| PRKAA1 | phosphorylation up-regulates → | HDAC7 PSer155 | phosphorylation down-regulates ⊣ | HDAC7 | 21892142 | SIGNOR-176487 |
| PRKAA1 | phosphorylation up-regulates → | ACACA PSer1201 | phosphorylation down-regulates ⊣ | ACACA | 7907095 | SIGNOR-250400 |
| PRKAA1 | phosphorylation up-regulates → | HDAC5 PSer259 | phosphorylation down-regulates ⊣ | HDAC5 | 21892142 | SIGNOR-176479 |
| PRKAA1 | phosphorylation up-regulates → | HNF4A PSer303 | phosphorylation down-regulates ⊣ | HNF4A | 12740371 | SIGNOR-101101 |
| PRKAA1 | phosphorylation up-regulates → | FOXO PSer588 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252978 |
| PRKAA1 | phosphorylation up-regulates → | EGLN1 PSer61 | phosphorylation down-regulates ⊣ | EGLN1 | 35538889 | SIGNOR-277592 |
| PRKAA1 | phosphorylation up-regulates → | KIF4A PSer801 | phosphorylation up-regulates → | KIF4A | 28992084 | SIGNOR-265991 |
| PRKAA1 | phosphorylation up-regulates → | INSIG1 PThr222 | phosphorylation up-regulates → | INSIG1 | 30733434 | SIGNOR-277430 |
| PRKAA1 | phosphorylation up-regulates → | BTRC PSer82 | phosphorylation down-regulates ⊣ | BTRC | 31406304 | SIGNOR-277475 |
| PRKAA1 | phosphorylation up-regulates → | FOXO PSer626 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252979 |
| PRKAA1 | phosphorylation up-regulates → | EEF2K PSer78 | phosphorylation down-regulates ⊣ | EEF2K | 14709557 | SIGNOR-250314 |
| PRKAA1 | phosphorylation up-regulates → | GLI1 PSer408 | phosphorylation down-regulates ⊣ | GLI1 | 26190112 | SIGNOR-259863 |
| PRKAA1 | phosphorylation up-regulates → | KCNA5 PSer592 | phosphorylation down-regulates ⊣ | KCNA5 | 30279167 | SIGNOR-277814 |
| PRKAA1 | phosphorylation up-regulates → | GLI1 PThr1074 | phosphorylation down-regulates ⊣ | GLI1 | 26190112 | SIGNOR-259862 |
| PRKAA1 | phosphorylation up-regulates → | MAPT PSer214 | phosphorylation down-regulates ⊣ | MAPT | 10090741 | SIGNOR-275439 |
| PRKAA1 | phosphorylation up-regulates → | NOS3 PSer1177 | phosphorylation up-regulates → | NOS3 | 18303014 | SIGNOR-160838 |
| PRKAA1 | phosphorylation up-regulates → | GLI1 PSer102 | phosphorylation down-regulates ⊣ | GLI1 | 26190112 | SIGNOR-259861 |
| PRKAA1 | phosphorylation up-regulates → | HIPK2 PThr1114 | phosphorylation up-regulates → | HIPK2 | 23871434 | SIGNOR-276469 |
| PRKAA1 | phosphorylation up-regulates → | RBBP7 PSer314 | phosphorylation up-regulates → | RBBP7 | 28143904 | SIGNOR-264784 |
| PRKAA1 | phosphorylation up-regulates → | DDIT3 PSer30 | phosphorylation down-regulates ⊣ | DDIT3 | 27650555 | SIGNOR-259864 |
| PRKAA1 | phosphorylation up-regulates → | CFTR PSer768 | phosphorylation down-regulates ⊣ | CFTR | 19095655 | SIGNOR-259867 |
| PRKAA1 | phosphorylation up-regulates → | NOS3 PThr495 | phosphorylation up-regulates → | NOS3 | 24379783 | SIGNOR-251619 |
| PRKAA1 | phosphorylation up-regulates → | KCNA5 PSer559 | phosphorylation down-regulates ⊣ | KCNA5 | 30279167 | SIGNOR-277813 |
| PRKAA1 | phosphorylation up-regulates → | PPARGC1A PSer539 | phosphorylation up-regulates → | PPARGC1A | 17609368 | SIGNOR-228654 |
| PRKAA1 | phosphorylation up-regulates → | FOXO3 PSer399 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-249667 |
| PRKAA1 | phosphorylation up-regulates → | PIAS1 PSer510 | phosphorylation up-regulates → | PIAS1 | 27256105 | SIGNOR-259866 |
| PRKAA1 | phosphorylation up-regulates → | MAPT PSer267 | phosphorylation down-regulates ⊣ | MAPT | 10090741 | SIGNOR-275438 |
| PRKAA1 | phosphorylation up-regulates → | PRPS2 PSer180 | phosphorylation down-regulates ⊣ | PRPS2 | 29074724 | SIGNOR-265731 |
| PRKAA1 | phosphorylation up-regulates → | TBC1D1 PSer237 | phosphorylation down-regulates ⊣ | TBC1D1 | 17995453 | SIGNOR-159048 |
| PRKAA1 | phosphorylation up-regulates → | FOXO PSer399 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252975 |
| PRKAA1 | phosphorylation up-regulates → | GAPDH PSer122 | phosphorylation up-regulates → | GAPDH | 26626483 | SIGNOR-259857 |
| PRKAA1 | phosphorylation up-regulates → | HDAC5 PSer498 | phosphorylation down-regulates ⊣ | HDAC5 | 21892142 | SIGNOR-176483 |
| PRKAA1 | phosphorylation up-regulates → | GFPT1 PSer242 | phosphorylation down-regulates ⊣ | GFPT1 | 19170765 | SIGNOR-183528 |
| PRKAA1 | phosphorylation up-regulates → | RPTOR PSer792 | phosphorylation down-regulates ⊣ | RPTOR | 18439900 | SIGNOR-161375 |
| PRKAA1 | phosphorylation up-regulates → | STIM1 PSer257 | phosphorylation down-regulates ⊣ | STIM1 | 31381180 | SIGNOR-277299 |
| PRKAA1 | phosphorylation up-regulates → | EEF2K PSer366 | phosphorylation down-regulates ⊣ | EEF2K | 14709557 | SIGNOR-250402 |
| PRKAA1 | phosphorylation up-regulates → | POU2F1 PSer385 | phosphorylation down-regulates ⊣ | POU2F1 | 1684878 | SIGNOR-20971 |
| PRKAA1 | phosphorylation up-regulates → | PDHA1 PSer295 | phosphorylation up-regulates → | PDHA1 | 33022274 | SIGNOR-276837 |
| PRKAA1 | phosphorylation up-regulates → | MAPT PSer355 | phosphorylation down-regulates ⊣ | MAPT | 10090741 | SIGNOR-275440 |
| PRKAA1 | phosphorylation up-regulates → | MFF PSer172 | phosphorylation up-regulates → | MFF | 26816379 | SIGNOR-249656 |
| PRKAA1 | phosphorylation up-regulates → | MCU PSer57 | phosphorylation up-regulates → | MCU | 30858581 | SIGNOR-275547 |
| PRKAA1 | phosphorylation up-regulates → | LIPE PSer855 | phosphorylation down-regulates ⊣ | LIPE | 9636039 | SIGNOR-58255 |
| PRKAA1 | phosphorylation up-regulates → | CDKN1B PThr198 | phosphorylation up-regulates → | CDKN1B | 30033086 | SIGNOR-259859 |
| PRKAA1 | phosphorylation up-regulates → | KCNA5 PSer592 | phosphorylation down-regulates ⊣ | KCNA5 | 30279167 | SIGNOR-277800 |
| PRKAA1 | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 15866171 | SIGNOR-135960 |
| PRKAA1 | phosphorylation up-regulates → | GSR PThr507 | phosphorylation up-regulates → | GSR | 31530934 | SIGNOR-273734 |
| PRKAA1 | phosphorylation up-regulates → | CCNY PSer326 | phosphorylation up-regulates → | CCNY | 32723157 | SIGNOR-273011 |
| PRKAA1 | phosphorylation up-regulates → | FOXO3 PSer588 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-249684 |
| PRKAA1 | phosphorylation up-regulates → | FOXO3 PThr179 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-238804 |
| PRKAA1 | phosphorylation up-regulates → | GBF1 PThr1337 | phosphorylation down-regulates ⊣ | GBF1 | 18063581 | SIGNOR-159639 |
| PRKAA1 | phosphorylation up-regulates → | PPARGC1A PThr178 | phosphorylation up-regulates → | PPARGC1A | 17609368 | SIGNOR-156780 |
| PRKAA1 | phosphorylation up-regulates → | SNAI1 PSer92 | phosphorylation up-regulates → | SNAI1 | 19923321 | SIGNOR-161783 |
| PRKAA1 | phosphorylation up-regulates → | SYN1 PSer9 | phosphorylation down-regulates ⊣ | SYN1 | 10880969 | SIGNOR-78891 |
| PRKAA1 | phosphorylation up-regulates → | PRKAA1 PSer486 | phosphorylation down-regulates ⊣ | PRKAA1 | 17023420 | SIGNOR-256114 |
| PRKAA1 | phosphorylation up-regulates → | HDAC7 PSer358 | phosphorylation down-regulates ⊣ | HDAC7 | 21892142 | SIGNOR-176491 |
| PRKAA1 | phosphorylation up-regulates → | FOXO PSer555 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252977 |
| PRKAA1 | phosphorylation up-regulates → | FANCA PSer347 | phosphorylation up-regulates → | FANCA | 27449087 | SIGNOR-277264 |
| PRKAA1 | phosphorylation up-regulates → | TET2 PSer99 | phosphorylation up-regulates → | TET2 | 30022161 | SIGNOR-256134 |
| PRKAA1 | phosphorylation up-regulates → | GFPT1 PSer261 | phosphorylation up-regulates → | GFPT1 | 17941647 | SIGNOR-158490 |
| PRKAA1 | phosphorylation up-regulates → | PFKFB3 PSer461 | phosphorylation up-regulates → | PFKFB3 | 12065600 | SIGNOR-89760 |
| PRKAA1 | phosphorylation up-regulates → | SIRT7 PThr153 | phosphorylation down-regulates ⊣ | SIRT7 | 27511885 | SIGNOR-275864 |
| PRKAA1 | phosphorylation up-regulates → | DNMT1 PSer714 | phosphorylation down-regulates ⊣ | DNMT1 | 28143904 | SIGNOR-264783 |
| PRKAA1 | phosphorylation up-regulates → | RB1 PSer811 | phosphorylation down-regulates ⊣ | RB1 | 19217427 | SIGNOR-184052 |
| PRKAA1 | phosphorylation up-regulates → | RAF1 PSer259 | phosphorylation down-regulates ⊣ | RAF1 | 11971957 | SIGNOR-86133 |
| PRKAA1 | phosphorylation up-regulates → | EEF2K PSer398 | phosphorylation up-regulates → | EEF2K | 14709557 | SIGNOR-250157 |
| PRKAA1 | phosphorylation up-regulates → | FOXO PThr179 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252980 |
| PRKAA1 | phosphorylation up-regulates → | FOXO PSer413 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252976 |
| PRKAA1 | phosphorylation up-regulates → | SCN5A PThr101 | phosphorylation down-regulates ⊣ | SCN5A | 30759345 | SIGNOR-277432 |
| PRKAA1 | phosphorylation up-regulates → | FOXO3 PSer555 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-249681 |
| PRKAA1 | phosphorylation up-regulates → | FOXO3 PSer413 | phosphorylation up-regulates → | FOXO3 | 17711846 | SIGNOR-249677 |
| PRKAA1 | phosphorylation up-regulates → | GLI1 PSer408 | phosphorylation down-regulates ⊣ | GLI1 | 26190112 | SIGNOR-259860 |
| PRKAA1 | phosphorylation up-regulates → | PDHA1 PSer314 | phosphorylation up-regulates → | PDHA1 | 33022274 | SIGNOR-276839 |
| PRKAA1 | phosphorylation up-regulates → | PRPS1 PSer180 | phosphorylation down-regulates ⊣ | PRPS1 | 29074724 | SIGNOR-265729 |
| PRKAA1 | phosphorylation up-regulates → | EEF2K PSer398 | phosphorylation up-regulates → | EEF2K | 22669845 | SIGNOR-197734 |
| PRKAA1 | phosphorylation up-regulates → | ALDH2 PThr356 | phosphorylation up-regulates → | ALDH2 | 30375985 | SIGNOR-271863 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKAA1 | phosphorylation → down-regulates activity | CFTR | SIGNOR-259858 |
| PRKAA1 | phosphorylation down-regulates | EP300 | SIGNOR-176637 |
| PRKAA1 | phosphorylation → up-regulates | PRKAB1 | SIGNOR-157553 |
| PRKAA1 | phosphorylation → up-regulates quantity by stabilization | SNAI1 | SIGNOR-161779 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-249687 |
| PRKAA1 | phosphorylation down-regulates | HDAC4 | SIGNOR-173689 |
| PRKAA1 | phosphorylation → up-regulates activity | USP10 | SIGNOR-277207 |
| PRKAA1 | phosphorylation down-regulates | RRN3 | SIGNOR-188403 |
| PRKAA1 | phosphorylation → down-regulates activity | SREBF1 | SIGNOR-176497 |
| PRKAA1 | phosphorylation down-regulates | CRTC2 | SIGNOR-176426 |
| PRKAA1 | phosphorylation → down-regulates activity | SIRT1 | SIGNOR-280076 |
| PRKAA1 | phosphorylation → up-regulates | KPNA2 | SIGNOR-128629 |
| PRKAA1 | phosphorylation → up-regulates | KLC2 | SIGNOR-174681 |
| PRKAA1 | phosphorylation → down-regulates activity | KCNA5 | SIGNOR-277799 |
| PRKAA1 | phosphorylation → up-regulates activity | PFKFB2 | SIGNOR-260012 |
| PRKAA1 | phosphorylation down-regulates | RAF1 | SIGNOR-47148 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO | SIGNOR-252983 |
| PRKAA1 | phosphorylation → up-regulates activity | MFF | SIGNOR-245953 |
| PRKAA1 | phosphorylation down-regulates | NR2C2 | SIGNOR-173118 |
| PRKAA1 | phosphorylation → up-regulates activity | NFE2L2 | SIGNOR-277494 |
| PRKAA1 | phosphorylation → up-regulates activity | PFKFB2 | SIGNOR-84061 |
| PRKAA1 | phosphorylation → up-regulates activity | ACSS2 | SIGNOR-271822 |
| PRKAA1 | phosphorylation → down-regulates quantity | DDIT3 | SIGNOR-278381 |
| PRKAA1 | phosphorylation → up-regulates activity | HIPK2 | SIGNOR-276467 |
| PRKAA1 | phosphorylation → down-regulates activity | EGLN1 | SIGNOR-277593 |
| PRKAA1 | phosphorylation → up-regulates activity | HIPK2 | SIGNOR-276468 |
| PRKAA1 | phosphorylation → up-regulates activity | NFE2L2 | SIGNOR-277495 |
| PRKAA1 | phosphorylation → up-regulates activity | NFE2L2 | SIGNOR-277496 |
| PRKAA1 | phosphorylation down-regulates | CRY1 | SIGNOR-176472 |
| PRKAA1 | phosphorylation down-regulates | POU2F1 | SIGNOR-53254 |
| PRKAA1 | phosphorylation → up-regulates activity | ULK1 | SIGNOR-173038 |
| PRKAA1 | phosphorylation down-regulates | ZNF692 | SIGNOR-150590 |
| PRKAA1 | phosphorylation → up-regulates activity | TSC2 | SIGNOR-278981 |
| PRKAA1 | phosphorylation → up-regulates activity | HAT1 | SIGNOR-264782 |
| PRKAA1 | phosphorylation down-regulates | CTBP1 | SIGNOR-200250 |
| PRKAA1 | phosphorylation down-regulates | HDAC7 | SIGNOR-176487 |
| PRKAA1 | phosphorylation → down-regulates activity | ACACA | SIGNOR-250400 |
| PRKAA1 | phosphorylation down-regulates | HDAC5 | SIGNOR-176479 |
| PRKAA1 | phosphorylation → down-regulates activity | HNF4A | SIGNOR-101101 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO | SIGNOR-252978 |
| PRKAA1 | phosphorylation → down-regulates activity | EGLN1 | SIGNOR-277592 |
| PRKAA1 | phosphorylation → up-regulates activity | KIF4A | SIGNOR-265991 |
| PRKAA1 | phosphorylation → up-regulates quantity by stabilization | INSIG1 | SIGNOR-277430 |
| PRKAA1 | phosphorylation down-regulates quantity by destabilization | BTRC | SIGNOR-277475 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO | SIGNOR-252979 |
| PRKAA1 | phosphorylation → down-regulates activity | EEF2K | SIGNOR-250314 |
| PRKAA1 | phosphorylation → down-regulates activity | GLI1 | SIGNOR-259863 |
| PRKAA1 | phosphorylation → down-regulates activity | KCNA5 | SIGNOR-277814 |
| PRKAA1 | phosphorylation → up-regulates | FOXO | SIGNOR-252981 |
| PRKAA1 | phosphorylation → down-regulates activity | GLI1 | SIGNOR-259862 |
| PRKAA1 | phosphorylation → down-regulates activity | MAPT | SIGNOR-275439 |
| PRKAA1 | phosphorylation → up-regulates | NOS3 | SIGNOR-160838 |
| PRKAA1 | phosphorylation → down-regulates activity | GLI1 | SIGNOR-259861 |
| PRKAA1 | phosphorylation → up-regulates activity | HIPK2 | SIGNOR-276469 |
| PRKAA1 | phosphorylation → up-regulates activity | RBBP7 | SIGNOR-264784 |
| PRKAA1 | phosphorylation → down-regulates activity | DDIT3 | SIGNOR-259864 |
| PRKAA1 | phosphorylation → down-regulates activity | CFTR | SIGNOR-259867 |
| PRKAA1 | phosphorylation → up-regulates activity | NOS3 | SIGNOR-251619 |
| PRKAA1 | phosphorylation → down-regulates activity | KCNA5 | SIGNOR-277813 |
| PRKAA1 | phosphorylation → up-regulates activity | PPARGC1A | SIGNOR-228654 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-255755 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-249667 |
| PRKAA1 | phosphorylation → up-regulates activity | PIAS1 | SIGNOR-259866 |
| PRKAA1 | phosphorylation → down-regulates activity | MAPT | SIGNOR-275438 |
| PRKAA1 | phosphorylation → down-regulates activity | PRPS2 | SIGNOR-265731 |
| PRKAA1 | phosphorylation down-regulates | TBC1D1 | SIGNOR-159048 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO | SIGNOR-252975 |
| PRKAA1 | phosphorylation → up-regulates activity | GAPDH | SIGNOR-259857 |
| PRKAA1 | phosphorylation down-regulates | HDAC5 | SIGNOR-176483 |
| PRKAA1 | phosphorylation down-regulates | MLXIPL | SIGNOR-112289 |
| PRKAA1 | phosphorylation down-regulates | GFPT1 | SIGNOR-183528 |
| PRKAA1 | phosphorylation → down-regulates activity | RPTOR | SIGNOR-161375 |
| PRKAA1 | phosphorylation → down-regulates activity | STIM1 | SIGNOR-277299 |
| PRKAA1 | phosphorylation → down-regulates activity | EEF2K | SIGNOR-250402 |
| PRKAA1 | phosphorylation down-regulates | POU2F1 | SIGNOR-20971 |
| PRKAA1 | phosphorylation → up-regulates activity | PDHA1 | SIGNOR-276837 |
| PRKAA1 | phosphorylation → down-regulates activity | MAPT | SIGNOR-275440 |
| PRKAA1 | phosphorylation down-regulates | MLXIPL | SIGNOR-176494 |
| PRKAA1 | phosphorylation → up-regulates activity | MFF | SIGNOR-249656 |
| PRKAA1 | phosphorylation → up-regulates activity | MCU | SIGNOR-275547 |
| PRKAA1 | phosphorylation down-regulates | LIPE | SIGNOR-58255 |
| PRKAA1 | phosphorylation → up-regulates quantity by stabilization | CDKN1B | SIGNOR-259859 |
| PRKAA1 | phosphorylation down-regulates | CRTC1 | SIGNOR-172136 |
| PRKAA1 | phosphorylation → down-regulates activity | KCNA5 | SIGNOR-277800 |
| PRKAA1 | phosphorylation → up-regulates | TP53 | SIGNOR-135960 |
| PRKAA1 | phosphorylation → up-regulates activity | GSR | SIGNOR-273734 |
| PRKAA1 | phosphorylation → up-regulates activity | CCNY | SIGNOR-273011 |
| PRKAA1 | phosphorylation → down-regulates activity | RPTOR | SIGNOR-173035 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-249684 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-238804 |
| PRKAA1 | phosphorylation down-regulates | GBF1 | SIGNOR-159639 |
| PRKAA1 | phosphorylation → up-regulates activity | PPARGC1A | SIGNOR-156780 |
| PRKAA1 | phosphorylation → up-regulates | FOXO4 | SIGNOR-157947 |
| PRKAA1 | phosphorylation → up-regulates | SNAI1 | SIGNOR-161783 |
| PRKAA1 | phosphorylation → down-regulates activity | SYN1 | SIGNOR-78891 |
| PRKAA1 | phosphorylation → down-regulates activity | PRKAA1 | SIGNOR-256114 |
| PRKAA1 | phosphorylation down-regulates | HDAC7 | SIGNOR-176491 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO | SIGNOR-252977 |
| PRKAA1 | phosphorylation → up-regulates activity | FANCA | SIGNOR-277264 |
| PRKAA1 | phosphorylation → up-regulates quantity by stabilization | TET2 | SIGNOR-256134 |
| PRKAA1 | phosphorylation → up-regulates | GFPT1 | SIGNOR-158490 |
| PRKAA1 | phosphorylation → up-regulates | PFKFB3 | SIGNOR-89760 |
| PRKAA1 | phosphorylation down-regulates quantity by destabilization | SIRT7 | SIGNOR-275864 |
| PRKAA1 | phosphorylation → down-regulates activity | DNMT1 | SIGNOR-264783 |
| PRKAA1 | phosphorylation down-regulates | RB1 | SIGNOR-184052 |
| PRKAA1 | phosphorylation down-regulates | RAF1 | SIGNOR-86133 |
| PRKAA1 | phosphorylation → up-regulates activity | EEF2K | SIGNOR-250157 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO | SIGNOR-252980 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO | SIGNOR-252976 |
| PRKAA1 | phosphorylation down-regulates quantity by destabilization | SCN5A | SIGNOR-277432 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-249681 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-249677 |
| PRKAA1 | phosphorylation → down-regulates activity | GLI1 | SIGNOR-259860 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO3 | SIGNOR-219247 |
| PRKAA1 | phosphorylation → up-regulates activity | PDHA1 | SIGNOR-276839 |
| PRKAA1 | phosphorylation → down-regulates activity | PRPS1 | SIGNOR-265729 |
| PRKAA1 | phosphorylation → up-regulates | EEF2K | SIGNOR-197734 |
| PRKAA1 | phosphorylation → up-regulates | FOXO1 | SIGNOR-157941 |
| PRKAA1 | phosphorylation → up-regulates activity | ALDH2 | SIGNOR-271863 |