Entity Details

Name AKT1_Ser496
ID Q13131
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1PRKAA1Ser496ATPQRSGsVSNYRSCphosphorylation
down-regulates activity		27784766SIGNOR-276461
PRKCAPRKAA1Ser496ATPQRSGsVSNYRSCphosphorylation
down-regulates activity		27784766SIGNOR-276459
PRKACAPRKAA1Ser496ATPQRSGsVSNYRSCphosphorylation
down-regulates activity		27784766SIGNOR-259865
PRKCBPRKAA1Ser496ATPQRSGsVSNYRSCphosphorylation
down-regulates activity		27784766SIGNOR-276460
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
PRKAA1
PSer496		phosphorylation
down-regulates
⊣		PRKAA127784766SIGNOR-276461
PRKCAphosphorylation
up-regulates
→
PRKAA1
PSer496		phosphorylation
down-regulates
⊣		PRKAA127784766SIGNOR-276459
PRKACAphosphorylation
up-regulates
→
PRKAA1
PSer496		phosphorylation
down-regulates
⊣		PRKAA127784766SIGNOR-259865
PRKCBphosphorylation
up-regulates
→
PRKAA1
PSer496		phosphorylation
down-regulates
⊣		PRKAA127784766SIGNOR-276460
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
→
down-regulates activity 		PRKAA1SIGNOR-276461
PRKCAphosphorylation
→
down-regulates activity 		PRKAA1SIGNOR-276459
PRKACAphosphorylation
→
down-regulates activity 		PRKAA1SIGNOR-259865
PRKCBphosphorylation
→
down-regulates activity 		PRKAA1SIGNOR-276460