Entity Details

Name PAK1
ID Q13153
Role kinase
Enzymatic Domains
CRIB 75-88
PROSITE-ProRule
Protein kinase 270-521
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PAK1MYL12Bphosphorylation
up-regulates activity
25860930SIGNOR-280053
PAK1ARHGEF2Ser886PVDPRRRsLPAGDALphosphorylation
down-regulates
19667072SIGNOR-187573
PAK1SLC6A2phosphorylation
down-regulates activity
15684429SIGNOR-280054
PAK1KIF2CSer192VNSVRRKsCLVKEVEphosphorylation
down-regulates
23055517SIGNOR-199084
PAK1CTTNSer405KTQTPPVsPAPQPTEphosphorylation
up-regulates
21079800SIGNOR-169690
PAK1RPA1Ser135APPAPAAsPAASSRPphosphorylation
up-regulates activity
33704464SIGNOR-279378
PAK1PGAM1Ser23WNLENRFsGWYDADLphosphorylation
down-regulates
12189148SIGNOR-91598
PAK1RAF1Ser338RPRGQRDsSYYWEIEphosphorylation
up-regulates
18775988SIGNOR-180808
PAK1MAP2K1Ser298RTPGRPLsSYGMDSRphosphorylation
up-regulates activity
12876277SIGNOR-236002
PAK1LIMK1Thr508PDRKKRYtVVGNPYWphosphorylation
up-regulates activity
10559936SIGNOR-72142
PAK1MID1phosphorylation
up-regulates activity
32421151SIGNOR-279307
PAK1BADSer75EIRSRHSsYPAGTEDphosphorylation
down-regulates
10611223SIGNOR-73529
PAK1DYNLL1Ser88VAILLFKsGphosphorylation
down-regulates
18084006SIGNOR-159995
PAK1PXNSer272ELDELMAsLSDFKIQphosphorylation
unknown
16717130SIGNOR-146842
PAK1NF2Ser518DTDMKRLsMEIEKEKphosphorylation
down-regulates
18071304SIGNOR-159764
PAK1ILKThr173DTFWKGTtRTRPRNGphosphorylation
up-regulates
17420447SIGNOR-154307
PAK1ARPC1BThr21HAWNKDRtQIAICPNphosphorylation
up-regulates
14749719SIGNOR-121642
PAK1PAK1Ser199PRPEHTKsVYTRSVIphosphorylation
up-regulates activity
9032240SIGNOR-250216
PAK1ELF3Ser207GTGASRSsHSSDSGGphosphorylation
up-regulates
17491012SIGNOR-154743
PAK1STIM1phosphorylation
up-regulates activity
29780159SIGNOR-279244
PAK1CTTNSer418TEERLPSsPVYEDAAphosphorylation
up-regulates
21079800SIGNOR-169694
PAK1SORT1Ser793RFLVHRYsVLQQHAEphosphorylation
down-regulates activity
31767632SIGNOR-273718
PAK1PGAM2Ser118QVKIWRRsFDIPPPPphosphorylation
down-regulates quantity by destabilization
24567357SIGNOR-280237
PAK1H3C1Ser11TKQTARKsTGGKAPRphosphorylation
unknown
12151336SIGNOR-91050
PAK1ARAFSer299KNLGYRDsGYYWEVPphosphorylation
up-regulates
15710605SIGNOR-236342
PAK1STMN1Ser38SVPEFPLsPPKKKDLphosphorylation
down-regulates
19162178SIGNOR-183503
PAK1SPENSer3486QPAPKQDsSPHLTSQphosphorylation
down-regulates activity
15824732SIGNOR-278968
PAK1PGAM1Ser118QVKIWRRsYDVPPPPphosphorylation
down-regulates
12189148SIGNOR-91594
PAK1NET1Ser152PTPAKRRsSALWSEMphosphorylation
down-regulates activity
15684429SIGNOR-263019
PAK1RUFY3phosphorylation
up-regulates quantity
25766321SIGNOR-279243
PAK1ATF2Ser62FGPARNDsVIVADQTphosphorylation
down-regulates activity
28918037SIGNOR-279377
PAK1TBCBSer128VRSFLKRsKLGRYNEphosphorylation
up-regulates
15831477SIGNOR-135460
PAK1HACE1Ser385LMKNKRDsTEITSILphosphorylation
down-regulates activity
29362425SIGNOR-255537
PAK1ESR1Ser305IKRSKKNsLALSLTAphosphorylation
up-regulates
12374744SIGNOR-94206
PAK1NET1Ser152PTPAKRRsSALWSEMphosphorylation
down-regulates activity
15684429SIGNOR-263017
PAK1NLRP3phosphorylation
up-regulates activity
33432150SIGNOR-278967
PAK1PLK1Ser49EVLVDPRsRRRYVRGphosphorylation
up-regulates
18427546SIGNOR-178353
PAK1PA2G4Thr261QYGLKMKtSRAFFSEphosphorylation
up-regulates
18283314SIGNOR-160963
PAK1FOXO1phosphorylation
down-regulates activity
12560069SIGNOR-279242
PAK1STMN1Ser16KELEKRAsGQAFELIphosphorylation
down-regulates
14645234SIGNOR-119483
PAK1RAF1Ser339PRGQRDSsYYWEIEAphosphorylation
up-regulates
18775988SIGNOR-180812
PAK1MAP3K1Ser67RQLRKVRsVELDQLPphosphorylation
up-regulates activity
12228228SIGNOR-236006
PAK1CTTNSer418TEERLPSsPVYEDAAphosphorylation
up-regulates
20444238SIGNOR-165220
PAK1KIF2CSer111KESLRSRsTRMSTVSphosphorylation
down-regulates
23055517SIGNOR-199080
PAK1AJUBAphosphorylation
up-regulates activity
22105346SIGNOR-278449
PAK1PGM1Thr467SANDKVYtVEKADNFphosphorylation
up-regulates
15378030SIGNOR-127135
PAK1FXR1Ser420SERKDELsDWSLAGEphosphorylation
up-regulates activity
20417602SIGNOR-273713
PAK1BADSer74VEIRSRHsSYPAGTEphosphorylation
down-regulates
22096607SIGNOR-177271
PAK1CTNNB1Ser675QDYKKRLsVELTSSLphosphorylation
up-regulates
21822311SIGNOR-175944
PAK1ARHGDIASer101LESFKKQsFVLKEGVphosphorylation
down-regulates
15225553SIGNOR-126650
PAK1SYN1Ser605AGPTRQAsQAGPVPRphosphorylation
up-regulates activity
12237306SIGNOR-250235
PAK1ARHGDIASer174 KGMLARGsYSIKSRFphosphorylation
down-regulates
15225553SIGNOR-126654
PAK1WEE1phosphorylation
down-regulates
15037762SIGNOR-123528
PAK1RPA1Thr180LSHTSGGtQSKVVPIphosphorylation
up-regulates activity
33704464SIGNOR-279379
PAK1ILKSer246CPRLRIFsHPNVLPVphosphorylation
up-regulates
17420447SIGNOR-154303
PAK1CTTNSer405KTQTPPVsPAPQPTEphosphorylation
up-regulates
20444238SIGNOR-165216
PAK1TBCBSer65GVDDKFYsKLDQEDAphosphorylation
up-regulates
15831477SIGNOR-135464
PAK1MORC2Ser739ATPSRKRsVAVSDEEphosphorylation
up-regulates activity
25888627SIGNOR-273714
PAK1PREX2Ser1107DTISNRDsYSDCNSNphosphorylation
down-regulates activity
26438819SIGNOR-277181
PAK1BADSer99PFRGRSRsAPPNLWAphosphorylation
down-regulates
10611223SIGNOR-73533
PAK1NET1Ser539LTAQRRAsTVSSVTQphosphorylation
down-regulates activity
15684429SIGNOR-263018
PAK1MEK1/2phosphorylation
up-regulates activity
12876277SIGNOR-244924
PAK1PGAMphosphorylation
down-regulates
12189148SIGNOR-270283
PAK1CTBP1Ser158REGTRVQsVEQIREVphosphorylation
down-regulates activity
12872159SIGNOR-103943
PAK1ITGB3BPSer28SKITRKKsVITYSPTphosphorylation
up-regulates
18521086SIGNOR-178795
PAK1AURKAThr288APSSRRTtLCGTLDYphosphorylation
up-regulates
24867643SIGNOR-205110
PAK1MYLKphosphorylation
down-regulates activity
10092231SIGNOR-250317
PAK1Histone H3phosphorylation
unknown
12151336SIGNOR-265363
PAK1SNAI1Ser246QACARTFsRMSLLHKphosphorylation
up-regulates
15833848SIGNOR-135605
PAK1PAK1Ser57KKDRFYRsILPGDKTphosphorylation
up-regulates activity
9032240SIGNOR-250219
PAK1VIMSer56SRSLYASsPGGVYATphosphorylation
unknown
15766329SIGNOR-134520
PAK1STMN1Ser38SVPEFPLsPPKKKDLphosphorylation
down-regulates
10913145SIGNOR-79955
PAK1FLNASer2152TRRRRAPsVANVGSHphosphorylation
up-regulates
12198493SIGNOR-92065
PAK1BCL6phosphorylation
down-regulates activity
22723377SIGNOR-253930
PAK1ATG5Thr101SALPWNItVHFKSFPphosphorylation
up-regulates quantity by stabilization
36528756SIGNOR-275835
PAK1MORC2Ser739ATPSRKRsVAVSDEEphosphorylation
up-regulates activity
23260667SIGNOR-278414
PAK1NLRP3Thr659KIEINLStRMDHMVSphosphorylation
up-regulates activity
33432150SIGNOR-277547
PAK1GNAZSer16EKEAARRsRRIDRHLphosphorylation
up-regulates
9166747SIGNOR-48673
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PAK1phosphorylation
up-regulates
ARHGEF2
PSer886
phosphorylation
down-regulates
ARHGEF219667072SIGNOR-187573
PAK1phosphorylation
up-regulates
KIF2C
PSer192
phosphorylation
down-regulates
KIF2C23055517SIGNOR-199084
PAK1phosphorylation
up-regulates
CTTN
PSer405
phosphorylation
up-regulates
CTTN21079800SIGNOR-169690
PAK1phosphorylation
up-regulates
RPA1
PSer135
phosphorylation
up-regulates
RPA133704464SIGNOR-279378
PAK1phosphorylation
up-regulates
PGAM1
PSer23
phosphorylation
down-regulates
PGAM112189148SIGNOR-91598
PAK1phosphorylation
up-regulates
RAF1
PSer338
phosphorylation
up-regulates
RAF118775988SIGNOR-180808
PAK1phosphorylation
up-regulates
MAP2K1
PSer298
phosphorylation
up-regulates
MAP2K112876277SIGNOR-236002
PAK1phosphorylation
up-regulates
LIMK1
PThr508
phosphorylation
up-regulates
LIMK110559936SIGNOR-72142
PAK1phosphorylation
up-regulates
BAD
PSer75
phosphorylation
down-regulates
BAD10611223SIGNOR-73529
PAK1phosphorylation
up-regulates
DYNLL1
PSer88
phosphorylation
down-regulates
DYNLL118084006SIGNOR-159995
PAK1phosphorylation
up-regulates
PXN
PSer272
phosphorylation
down-regulates
PXN16717130SIGNOR-146842
PAK1phosphorylation
up-regulates
NF2
PSer518
phosphorylation
down-regulates
NF218071304SIGNOR-159764
PAK1phosphorylation
up-regulates
ILK
PThr173
phosphorylation
up-regulates
ILK17420447SIGNOR-154307
PAK1phosphorylation
up-regulates
ARPC1B
PThr21
phosphorylation
up-regulates
ARPC1B14749719SIGNOR-121642
PAK1phosphorylation
up-regulates
PAK1
PSer199
phosphorylation
up-regulates
PAK19032240SIGNOR-250216
PAK1phosphorylation
up-regulates
ELF3
PSer207
phosphorylation
up-regulates
ELF317491012SIGNOR-154743
PAK1phosphorylation
up-regulates
CTTN
PSer418
phosphorylation
up-regulates
CTTN21079800SIGNOR-169694
PAK1phosphorylation
up-regulates
SORT1
PSer793
phosphorylation
down-regulates
SORT131767632SIGNOR-273718
PAK1phosphorylation
up-regulates
PGAM2
PSer118
phosphorylation
down-regulates
PGAM224567357SIGNOR-280237
PAK1phosphorylation
up-regulates
H3C1
PSer11
phosphorylation
down-regulates
H3C112151336SIGNOR-91050
PAK1phosphorylation
up-regulates
ARAF
PSer299
phosphorylation
up-regulates
ARAF15710605SIGNOR-236342
PAK1phosphorylation
up-regulates
STMN1
PSer38
phosphorylation
down-regulates
STMN119162178SIGNOR-183503
PAK1phosphorylation
up-regulates
SPEN
PSer3486
phosphorylation
down-regulates
SPEN15824732SIGNOR-278968
PAK1phosphorylation
up-regulates
PGAM1
PSer118
phosphorylation
down-regulates
PGAM112189148SIGNOR-91594
PAK1phosphorylation
up-regulates
NET1
PSer152
phosphorylation
down-regulates
NET115684429SIGNOR-263019
PAK1phosphorylation
up-regulates
ATF2
PSer62
phosphorylation
down-regulates
ATF228918037SIGNOR-279377
PAK1phosphorylation
up-regulates
TBCB
PSer128
phosphorylation
up-regulates
TBCB15831477SIGNOR-135460
PAK1phosphorylation
up-regulates
HACE1
PSer385
phosphorylation
down-regulates
HACE129362425SIGNOR-255537
PAK1phosphorylation
up-regulates
ESR1
PSer305
phosphorylation
up-regulates
ESR112374744SIGNOR-94206
PAK1phosphorylation
up-regulates
NET1
PSer152
phosphorylation
down-regulates
NET115684429SIGNOR-263017
PAK1phosphorylation
up-regulates
PLK1
PSer49
phosphorylation
up-regulates
PLK118427546SIGNOR-178353
PAK1phosphorylation
up-regulates
PA2G4
PThr261
phosphorylation
up-regulates
PA2G418283314SIGNOR-160963
PAK1phosphorylation
up-regulates
STMN1
PSer16
phosphorylation
down-regulates
STMN114645234SIGNOR-119483
PAK1phosphorylation
up-regulates
RAF1
PSer339
phosphorylation
up-regulates
RAF118775988SIGNOR-180812
PAK1phosphorylation
up-regulates
MAP3K1
PSer67
phosphorylation
up-regulates
MAP3K112228228SIGNOR-236006
PAK1phosphorylation
up-regulates
CTTN
PSer418
phosphorylation
up-regulates
CTTN20444238SIGNOR-165220
PAK1phosphorylation
up-regulates
KIF2C
PSer111
phosphorylation
down-regulates
KIF2C23055517SIGNOR-199080
PAK1phosphorylation
up-regulates
PGM1
PThr467
phosphorylation
up-regulates
PGM115378030SIGNOR-127135
PAK1phosphorylation
up-regulates
FXR1
PSer420
phosphorylation
up-regulates
FXR120417602SIGNOR-273713
PAK1phosphorylation
up-regulates
BAD
PSer74
phosphorylation
down-regulates
BAD22096607SIGNOR-177271
PAK1phosphorylation
up-regulates
CTNNB1
PSer675
phosphorylation
up-regulates
CTNNB121822311SIGNOR-175944
PAK1phosphorylation
up-regulates
ARHGDIA
PSer101
phosphorylation
down-regulates
ARHGDIA15225553SIGNOR-126650
PAK1phosphorylation
up-regulates
SYN1
PSer605
phosphorylation
up-regulates
SYN112237306SIGNOR-250235
PAK1phosphorylation
up-regulates
ARHGDIA
PSer174
phosphorylation
down-regulates
ARHGDIA15225553SIGNOR-126654
PAK1phosphorylation
up-regulates
RPA1
PThr180
phosphorylation
up-regulates
RPA133704464SIGNOR-279379
PAK1phosphorylation
up-regulates
ILK
PSer246
phosphorylation
up-regulates
ILK17420447SIGNOR-154303
PAK1phosphorylation
up-regulates
CTTN
PSer405
phosphorylation
up-regulates
CTTN20444238SIGNOR-165216
PAK1phosphorylation
up-regulates
TBCB
PSer65
phosphorylation
up-regulates
TBCB15831477SIGNOR-135464
PAK1phosphorylation
up-regulates
MORC2
PSer739
phosphorylation
up-regulates
MORC225888627SIGNOR-273714
PAK1phosphorylation
up-regulates
PREX2
PSer1107
phosphorylation
down-regulates
PREX226438819SIGNOR-277181
PAK1phosphorylation
up-regulates
BAD
PSer99
phosphorylation
down-regulates
BAD10611223SIGNOR-73533
PAK1phosphorylation
up-regulates
NET1
PSer539
phosphorylation
down-regulates
NET115684429SIGNOR-263018
PAK1phosphorylation
up-regulates
CTBP1
PSer158
phosphorylation
down-regulates
CTBP112872159SIGNOR-103943
PAK1phosphorylation
up-regulates
ITGB3BP
PSer28
phosphorylation
up-regulates
ITGB3BP18521086SIGNOR-178795
PAK1phosphorylation
up-regulates
AURKA
PThr288
phosphorylation
up-regulates
AURKA24867643SIGNOR-205110
PAK1phosphorylation
up-regulates
SNAI1
PSer246
phosphorylation
up-regulates
SNAI115833848SIGNOR-135605
PAK1phosphorylation
up-regulates
PAK1
PSer57
phosphorylation
up-regulates
PAK19032240SIGNOR-250219
PAK1phosphorylation
up-regulates
VIM
PSer56
phosphorylation
down-regulates
VIM15766329SIGNOR-134520
PAK1phosphorylation
up-regulates
STMN1
PSer38
phosphorylation
down-regulates
STMN110913145SIGNOR-79955
PAK1phosphorylation
up-regulates
FLNA
PSer2152
phosphorylation
up-regulates
FLNA12198493SIGNOR-92065
PAK1phosphorylation
up-regulates
ATG5
PThr101
phosphorylation
up-regulates
ATG536528756SIGNOR-275835
PAK1phosphorylation
up-regulates
MORC2
PSer739
phosphorylation
up-regulates
MORC223260667SIGNOR-278414
PAK1phosphorylation
up-regulates
NLRP3
PThr659
phosphorylation
up-regulates
NLRP333432150SIGNOR-277547
PAK1phosphorylation
up-regulates
GNAZ
PSer16
phosphorylation
up-regulates
GNAZ9166747SIGNOR-48673
Regulator Mechanism/Effect Target SIGNOR-ID
PAK1phosphorylation

up-regulates activity
MYL12BSIGNOR-280053
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
ARHGEF2SIGNOR-187573
PAK1phosphorylation

down-regulates activity
SLC6A2SIGNOR-280054
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
KIF2CSIGNOR-199084
PAK1phosphorylation

up-regulates
CTTNSIGNOR-169690
PAK1phosphorylation

up-regulates activity
RPA1SIGNOR-279378
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
PGAM1SIGNOR-91598
PAK1phosphorylation

up-regulates
RAF1SIGNOR-180808
PAK1phosphorylation

up-regulates activity
MAP2K1SIGNOR-236002
PAK1phosphorylation

up-regulates activity
LIMK1SIGNOR-72142
PAK1phosphorylation

up-regulates activity
MID1SIGNOR-279307
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
BADSIGNOR-73529
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
DYNLL1SIGNOR-159995
PAK1phosphorylation

unknown
PXNSIGNOR-146842
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
NF2SIGNOR-159764
PAK1phosphorylation

up-regulates
ILKSIGNOR-154307
PAK1phosphorylation

up-regulates
ARPC1BSIGNOR-121642
PAK1phosphorylation

up-regulates activity
PAK1SIGNOR-250216
PAK1phosphorylation

up-regulates
ELF3SIGNOR-154743
PAK1phosphorylation

up-regulates activity
STIM1SIGNOR-279244
PAK1phosphorylation

up-regulates
CTTNSIGNOR-169694
PAK1phosphorylation

down-regulates activity
SORT1SIGNOR-273718
PAK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
PGAM2SIGNOR-280237
PAK1phosphorylation

unknown
H3C1SIGNOR-91050
PAK1phosphorylation

up-regulates
ARAFSIGNOR-236342
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
STMN1SIGNOR-183503
PAK1phosphorylation

down-regulates activity
SPENSIGNOR-278968
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
PGAM1SIGNOR-91594
PAK1phosphorylation

down-regulates activity
NET1SIGNOR-263019
PAK1phosphorylation

up-regulates quantity
RUFY3SIGNOR-279243
PAK1phosphorylation

down-regulates activity
ATF2SIGNOR-279377
PAK1phosphorylation

up-regulates
TBCBSIGNOR-135460
PAK1phosphorylation

down-regulates activity
HACE1SIGNOR-255537
PAK1phosphorylation

up-regulates
ESR1SIGNOR-94206
PAK1phosphorylation

down-regulates activity
NET1SIGNOR-263017
PAK1phosphorylation

up-regulates activity
NLRP3SIGNOR-278967
PAK1phosphorylation

up-regulates
PLK1SIGNOR-178353
PAK1phosphorylation

up-regulates
PA2G4SIGNOR-160963
PAK1phosphorylation

down-regulates activity
FOXO1SIGNOR-279242
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
STMN1SIGNOR-119483
PAK1phosphorylation

up-regulates
RAF1SIGNOR-180812
PAK1phosphorylation

up-regulates activity
MAP3K1SIGNOR-236006
PAK1phosphorylation

up-regulates
CTTNSIGNOR-165220
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
KIF2CSIGNOR-199080
PAK1phosphorylation

up-regulates activity
AJUBASIGNOR-278449
PAK1phosphorylation

up-regulates
PGM1SIGNOR-127135
PAK1phosphorylation

up-regulates activity
FXR1SIGNOR-273713
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
BADSIGNOR-177271
PAK1phosphorylation

up-regulates
CTNNB1SIGNOR-175944
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
ARHGDIASIGNOR-126650
PAK1phosphorylation

up-regulates activity
SYN1SIGNOR-250235
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
ARHGDIASIGNOR-126654
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
WEE1SIGNOR-123528
PAK1phosphorylation

up-regulates activity
RPA1SIGNOR-279379
PAK1phosphorylation

up-regulates
ILKSIGNOR-154303
PAK1phosphorylation

up-regulates
CTTNSIGNOR-165216
PAK1phosphorylation

up-regulates
TBCBSIGNOR-135464
PAK1phosphorylation

up-regulates activity
MORC2SIGNOR-273714
PAK1phosphorylation

down-regulates activity
PREX2SIGNOR-277181
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
BADSIGNOR-73533
PAK1phosphorylation

down-regulates activity
NET1SIGNOR-263018
PAK1phosphorylation

up-regulates activity
MEK1/2SIGNOR-244924
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
PGAMSIGNOR-270283
PAK1phosphorylation

down-regulates activity
CTBP1SIGNOR-103943
PAK1phosphorylation

up-regulates
ITGB3BPSIGNOR-178795
PAK1phosphorylation

up-regulates
AURKASIGNOR-205110
PAK1phosphorylation

down-regulates activity
MYLKSIGNOR-250317
PAK1phosphorylation

unknown
Histone H3SIGNOR-265363
PAK1phosphorylation

up-regulates
SNAI1SIGNOR-135605
PAK1phosphorylation

up-regulates activity
PAK1SIGNOR-250219
PAK1phosphorylation

unknown
VIMSIGNOR-134520
PAK1phosphorylation
img/direct_inhibition.png
down-regulates
STMN1SIGNOR-79955
PAK1phosphorylation

up-regulates
FLNASIGNOR-92065
PAK1phosphorylation

down-regulates activity
BCL6SIGNOR-253930
PAK1phosphorylation

up-regulates quantity by stabilization
ATG5SIGNOR-275835
PAK1phosphorylation

up-regulates activity
MORC2SIGNOR-278414
PAK1phosphorylation

up-regulates activity
NLRP3SIGNOR-277547
PAK1phosphorylation

up-regulates
GNAZSIGNOR-48673