| Name | PAK1 |
| ID | Q13153 |
| Role | kinase |
| Enzymatic Domains |
CRIB 75-88 PROSITE-ProRule
Protein kinase 270-521 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | MYL12B | – | phosphorylation up-regulates activity | 25860930 | SIGNOR-280053 | |
| PAK1 | ARHGEF2 | Ser886 | PVDPRRRsLPAGDAL | phosphorylation down-regulates | 19667072 | SIGNOR-187573 |
| PAK1 | SLC6A2 | – | phosphorylation down-regulates activity | 15684429 | SIGNOR-280054 | |
| PAK1 | KIF2C | Ser192 | VNSVRRKsCLVKEVE | phosphorylation down-regulates | 23055517 | SIGNOR-199084 |
| PAK1 | CTTN | Ser405 | KTQTPPVsPAPQPTE | phosphorylation up-regulates | 21079800 | SIGNOR-169690 |
| PAK1 | RPA1 | Ser135 | APPAPAAsPAASSRP | phosphorylation up-regulates activity | 33704464 | SIGNOR-279378 |
| PAK1 | PGAM1 | Ser23 | WNLENRFsGWYDADL | phosphorylation down-regulates | 12189148 | SIGNOR-91598 |
| PAK1 | RAF1 | Ser338 | RPRGQRDsSYYWEIE | phosphorylation up-regulates | 18775988 | SIGNOR-180808 |
| PAK1 | MAP2K1 | Ser298 | RTPGRPLsSYGMDSR | phosphorylation up-regulates activity | 12876277 | SIGNOR-236002 |
| PAK1 | LIMK1 | Thr508 | PDRKKRYtVVGNPYW | phosphorylation up-regulates activity | 10559936 | SIGNOR-72142 |
| PAK1 | MID1 | – | phosphorylation up-regulates activity | 32421151 | SIGNOR-279307 | |
| PAK1 | BAD | Ser75 | EIRSRHSsYPAGTED | phosphorylation down-regulates | 10611223 | SIGNOR-73529 |
| PAK1 | DYNLL1 | Ser88 | VAILLFKsG | phosphorylation down-regulates | 18084006 | SIGNOR-159995 |
| PAK1 | PXN | Ser272 | ELDELMAsLSDFKIQ | phosphorylation unknown | 16717130 | SIGNOR-146842 |
| PAK1 | NF2 | Ser518 | DTDMKRLsMEIEKEK | phosphorylation down-regulates | 18071304 | SIGNOR-159764 |
| PAK1 | ILK | Thr173 | DTFWKGTtRTRPRNG | phosphorylation up-regulates | 17420447 | SIGNOR-154307 |
| PAK1 | ARPC1B | Thr21 | HAWNKDRtQIAICPN | phosphorylation up-regulates | 14749719 | SIGNOR-121642 |
| PAK1 | PAK1 | Ser199 | PRPEHTKsVYTRSVI | phosphorylation up-regulates activity | 9032240 | SIGNOR-250216 |
| PAK1 | ELF3 | Ser207 | GTGASRSsHSSDSGG | phosphorylation up-regulates | 17491012 | SIGNOR-154743 |
| PAK1 | STIM1 | – | phosphorylation up-regulates activity | 29780159 | SIGNOR-279244 | |
| PAK1 | CTTN | Ser418 | TEERLPSsPVYEDAA | phosphorylation up-regulates | 21079800 | SIGNOR-169694 |
| PAK1 | SORT1 | Ser793 | RFLVHRYsVLQQHAE | phosphorylation down-regulates activity | 31767632 | SIGNOR-273718 |
| PAK1 | PGAM2 | Ser118 | QVKIWRRsFDIPPPP | phosphorylation down-regulates quantity by destabilization | 24567357 | SIGNOR-280237 |
| PAK1 | H3C1 | Ser11 | TKQTARKsTGGKAPR | phosphorylation unknown | 12151336 | SIGNOR-91050 |
| PAK1 | ARAF | Ser299 | KNLGYRDsGYYWEVP | phosphorylation up-regulates | 15710605 | SIGNOR-236342 |
| PAK1 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 19162178 | SIGNOR-183503 |
| PAK1 | SPEN | Ser3486 | QPAPKQDsSPHLTSQ | phosphorylation down-regulates activity | 15824732 | SIGNOR-278968 |
| PAK1 | PGAM1 | Ser118 | QVKIWRRsYDVPPPP | phosphorylation down-regulates | 12189148 | SIGNOR-91594 |
| PAK1 | NET1 | Ser152 | PTPAKRRsSALWSEM | phosphorylation down-regulates activity | 15684429 | SIGNOR-263019 |
| PAK1 | RUFY3 | – | phosphorylation up-regulates quantity | 25766321 | SIGNOR-279243 | |
| PAK1 | ATF2 | Ser62 | FGPARNDsVIVADQT | phosphorylation down-regulates activity | 28918037 | SIGNOR-279377 |
| PAK1 | TBCB | Ser128 | VRSFLKRsKLGRYNE | phosphorylation up-regulates | 15831477 | SIGNOR-135460 |
| PAK1 | HACE1 | Ser385 | LMKNKRDsTEITSIL | phosphorylation down-regulates activity | 29362425 | SIGNOR-255537 |
| PAK1 | ESR1 | Ser305 | IKRSKKNsLALSLTA | phosphorylation up-regulates | 12374744 | SIGNOR-94206 |
| PAK1 | NET1 | Ser152 | PTPAKRRsSALWSEM | phosphorylation down-regulates activity | 15684429 | SIGNOR-263017 |
| PAK1 | NLRP3 | – | phosphorylation up-regulates activity | 33432150 | SIGNOR-278967 | |
| PAK1 | PLK1 | Ser49 | EVLVDPRsRRRYVRG | phosphorylation up-regulates | 18427546 | SIGNOR-178353 |
| PAK1 | PA2G4 | Thr261 | QYGLKMKtSRAFFSE | phosphorylation up-regulates | 18283314 | SIGNOR-160963 |
| PAK1 | FOXO1 | – | phosphorylation down-regulates activity | 12560069 | SIGNOR-279242 | |
| PAK1 | STMN1 | Ser16 | KELEKRAsGQAFELI | phosphorylation down-regulates | 14645234 | SIGNOR-119483 |
| PAK1 | RAF1 | Ser339 | PRGQRDSsYYWEIEA | phosphorylation up-regulates | 18775988 | SIGNOR-180812 |
| PAK1 | MAP3K1 | Ser67 | RQLRKVRsVELDQLP | phosphorylation up-regulates activity | 12228228 | SIGNOR-236006 |
| PAK1 | CTTN | Ser418 | TEERLPSsPVYEDAA | phosphorylation up-regulates | 20444238 | SIGNOR-165220 |
| PAK1 | KIF2C | Ser111 | KESLRSRsTRMSTVS | phosphorylation down-regulates | 23055517 | SIGNOR-199080 |
| PAK1 | AJUBA | – | phosphorylation up-regulates activity | 22105346 | SIGNOR-278449 | |
| PAK1 | PGM1 | Thr467 | SANDKVYtVEKADNF | phosphorylation up-regulates | 15378030 | SIGNOR-127135 |
| PAK1 | FXR1 | Ser420 | SERKDELsDWSLAGE | phosphorylation up-regulates activity | 20417602 | SIGNOR-273713 |
| PAK1 | BAD | Ser74 | VEIRSRHsSYPAGTE | phosphorylation down-regulates | 22096607 | SIGNOR-177271 |
| PAK1 | CTNNB1 | Ser675 | QDYKKRLsVELTSSL | phosphorylation up-regulates | 21822311 | SIGNOR-175944 |
| PAK1 | ARHGDIA | Ser101 | LESFKKQsFVLKEGV | phosphorylation down-regulates | 15225553 | SIGNOR-126650 |
| PAK1 | SYN1 | Ser605 | AGPTRQAsQAGPVPR | phosphorylation up-regulates activity | 12237306 | SIGNOR-250235 |
| PAK1 | ARHGDIA | Ser174 | KGMLARGsYSIKSRF | phosphorylation down-regulates | 15225553 | SIGNOR-126654 |
| PAK1 | WEE1 | – | phosphorylation down-regulates | 15037762 | SIGNOR-123528 | |
| PAK1 | RPA1 | Thr180 | LSHTSGGtQSKVVPI | phosphorylation up-regulates activity | 33704464 | SIGNOR-279379 |
| PAK1 | ILK | Ser246 | CPRLRIFsHPNVLPV | phosphorylation up-regulates | 17420447 | SIGNOR-154303 |
| PAK1 | CTTN | Ser405 | KTQTPPVsPAPQPTE | phosphorylation up-regulates | 20444238 | SIGNOR-165216 |
| PAK1 | TBCB | Ser65 | GVDDKFYsKLDQEDA | phosphorylation up-regulates | 15831477 | SIGNOR-135464 |
| PAK1 | MORC2 | Ser739 | ATPSRKRsVAVSDEE | phosphorylation up-regulates activity | 25888627 | SIGNOR-273714 |
| PAK1 | PREX2 | Ser1107 | DTISNRDsYSDCNSN | phosphorylation down-regulates activity | 26438819 | SIGNOR-277181 |
| PAK1 | BAD | Ser99 | PFRGRSRsAPPNLWA | phosphorylation down-regulates | 10611223 | SIGNOR-73533 |
| PAK1 | NET1 | Ser539 | LTAQRRAsTVSSVTQ | phosphorylation down-regulates activity | 15684429 | SIGNOR-263018 |
| PAK1 | MEK1/2 | – | phosphorylation up-regulates activity | 12876277 | SIGNOR-244924 | |
| PAK1 | PGAM | – | phosphorylation down-regulates | 12189148 | SIGNOR-270283 | |
| PAK1 | CTBP1 | Ser158 | REGTRVQsVEQIREV | phosphorylation down-regulates activity | 12872159 | SIGNOR-103943 |
| PAK1 | ITGB3BP | Ser28 | SKITRKKsVITYSPT | phosphorylation up-regulates | 18521086 | SIGNOR-178795 |
| PAK1 | AURKA | Thr288 | APSSRRTtLCGTLDY | phosphorylation up-regulates | 24867643 | SIGNOR-205110 |
| PAK1 | MYLK | – | phosphorylation down-regulates activity | 10092231 | SIGNOR-250317 | |
| PAK1 | Histone H3 | – | phosphorylation unknown | 12151336 | SIGNOR-265363 | |
| PAK1 | SNAI1 | Ser246 | QACARTFsRMSLLHK | phosphorylation up-regulates | 15833848 | SIGNOR-135605 |
| PAK1 | PAK1 | Ser57 | KKDRFYRsILPGDKT | phosphorylation up-regulates activity | 9032240 | SIGNOR-250219 |
| PAK1 | VIM | Ser56 | SRSLYASsPGGVYAT | phosphorylation unknown | 15766329 | SIGNOR-134520 |
| PAK1 | STMN1 | Ser38 | SVPEFPLsPPKKKDL | phosphorylation down-regulates | 10913145 | SIGNOR-79955 |
| PAK1 | FLNA | Ser2152 | TRRRRAPsVANVGSH | phosphorylation up-regulates | 12198493 | SIGNOR-92065 |
| PAK1 | BCL6 | – | phosphorylation down-regulates activity | 22723377 | SIGNOR-253930 | |
| PAK1 | ATG5 | Thr101 | SALPWNItVHFKSFP | phosphorylation up-regulates quantity by stabilization | 36528756 | SIGNOR-275835 |
| PAK1 | MORC2 | Ser739 | ATPSRKRsVAVSDEE | phosphorylation up-regulates activity | 23260667 | SIGNOR-278414 |
| PAK1 | NLRP3 | Thr659 | KIEINLStRMDHMVS | phosphorylation up-regulates activity | 33432150 | SIGNOR-277547 |
| PAK1 | GNAZ | Ser16 | EKEAARRsRRIDRHL | phosphorylation up-regulates | 9166747 | SIGNOR-48673 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | phosphorylation up-regulates → | ARHGEF2 PSer886 | phosphorylation down-regulates ⊣ | ARHGEF2 | 19667072 | SIGNOR-187573 |
| PAK1 | phosphorylation up-regulates → | KIF2C PSer192 | phosphorylation down-regulates ⊣ | KIF2C | 23055517 | SIGNOR-199084 |
| PAK1 | phosphorylation up-regulates → | CTTN PSer405 | phosphorylation up-regulates → | CTTN | 21079800 | SIGNOR-169690 |
| PAK1 | phosphorylation up-regulates → | RPA1 PSer135 | phosphorylation up-regulates → | RPA1 | 33704464 | SIGNOR-279378 |
| PAK1 | phosphorylation up-regulates → | PGAM1 PSer23 | phosphorylation down-regulates ⊣ | PGAM1 | 12189148 | SIGNOR-91598 |
| PAK1 | phosphorylation up-regulates → | RAF1 PSer338 | phosphorylation up-regulates → | RAF1 | 18775988 | SIGNOR-180808 |
| PAK1 | phosphorylation up-regulates → | MAP2K1 PSer298 | phosphorylation up-regulates → | MAP2K1 | 12876277 | SIGNOR-236002 |
| PAK1 | phosphorylation up-regulates → | LIMK1 PThr508 | phosphorylation up-regulates → | LIMK1 | 10559936 | SIGNOR-72142 |
| PAK1 | phosphorylation up-regulates → | BAD PSer75 | phosphorylation down-regulates ⊣ | BAD | 10611223 | SIGNOR-73529 |
| PAK1 | phosphorylation up-regulates → | DYNLL1 PSer88 | phosphorylation down-regulates ⊣ | DYNLL1 | 18084006 | SIGNOR-159995 |
| PAK1 | phosphorylation up-regulates → | PXN PSer272 | phosphorylation down-regulates ⊣ | PXN | 16717130 | SIGNOR-146842 |
| PAK1 | phosphorylation up-regulates → | NF2 PSer518 | phosphorylation down-regulates ⊣ | NF2 | 18071304 | SIGNOR-159764 |
| PAK1 | phosphorylation up-regulates → | ILK PThr173 | phosphorylation up-regulates → | ILK | 17420447 | SIGNOR-154307 |
| PAK1 | phosphorylation up-regulates → | ARPC1B PThr21 | phosphorylation up-regulates → | ARPC1B | 14749719 | SIGNOR-121642 |
| PAK1 | phosphorylation up-regulates → | PAK1 PSer199 | phosphorylation up-regulates → | PAK1 | 9032240 | SIGNOR-250216 |
| PAK1 | phosphorylation up-regulates → | ELF3 PSer207 | phosphorylation up-regulates → | ELF3 | 17491012 | SIGNOR-154743 |
| PAK1 | phosphorylation up-regulates → | CTTN PSer418 | phosphorylation up-regulates → | CTTN | 21079800 | SIGNOR-169694 |
| PAK1 | phosphorylation up-regulates → | SORT1 PSer793 | phosphorylation down-regulates ⊣ | SORT1 | 31767632 | SIGNOR-273718 |
| PAK1 | phosphorylation up-regulates → | PGAM2 PSer118 | phosphorylation down-regulates ⊣ | PGAM2 | 24567357 | SIGNOR-280237 |
| PAK1 | phosphorylation up-regulates → | H3C1 PSer11 | phosphorylation down-regulates ⊣ | H3C1 | 12151336 | SIGNOR-91050 |
| PAK1 | phosphorylation up-regulates → | ARAF PSer299 | phosphorylation up-regulates → | ARAF | 15710605 | SIGNOR-236342 |
| PAK1 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 19162178 | SIGNOR-183503 |
| PAK1 | phosphorylation up-regulates → | SPEN PSer3486 | phosphorylation down-regulates ⊣ | SPEN | 15824732 | SIGNOR-278968 |
| PAK1 | phosphorylation up-regulates → | PGAM1 PSer118 | phosphorylation down-regulates ⊣ | PGAM1 | 12189148 | SIGNOR-91594 |
| PAK1 | phosphorylation up-regulates → | NET1 PSer152 | phosphorylation down-regulates ⊣ | NET1 | 15684429 | SIGNOR-263019 |
| PAK1 | phosphorylation up-regulates → | ATF2 PSer62 | phosphorylation down-regulates ⊣ | ATF2 | 28918037 | SIGNOR-279377 |
| PAK1 | phosphorylation up-regulates → | TBCB PSer128 | phosphorylation up-regulates → | TBCB | 15831477 | SIGNOR-135460 |
| PAK1 | phosphorylation up-regulates → | HACE1 PSer385 | phosphorylation down-regulates ⊣ | HACE1 | 29362425 | SIGNOR-255537 |
| PAK1 | phosphorylation up-regulates → | ESR1 PSer305 | phosphorylation up-regulates → | ESR1 | 12374744 | SIGNOR-94206 |
| PAK1 | phosphorylation up-regulates → | NET1 PSer152 | phosphorylation down-regulates ⊣ | NET1 | 15684429 | SIGNOR-263017 |
| PAK1 | phosphorylation up-regulates → | PLK1 PSer49 | phosphorylation up-regulates → | PLK1 | 18427546 | SIGNOR-178353 |
| PAK1 | phosphorylation up-regulates → | PA2G4 PThr261 | phosphorylation up-regulates → | PA2G4 | 18283314 | SIGNOR-160963 |
| PAK1 | phosphorylation up-regulates → | STMN1 PSer16 | phosphorylation down-regulates ⊣ | STMN1 | 14645234 | SIGNOR-119483 |
| PAK1 | phosphorylation up-regulates → | RAF1 PSer339 | phosphorylation up-regulates → | RAF1 | 18775988 | SIGNOR-180812 |
| PAK1 | phosphorylation up-regulates → | MAP3K1 PSer67 | phosphorylation up-regulates → | MAP3K1 | 12228228 | SIGNOR-236006 |
| PAK1 | phosphorylation up-regulates → | CTTN PSer418 | phosphorylation up-regulates → | CTTN | 20444238 | SIGNOR-165220 |
| PAK1 | phosphorylation up-regulates → | KIF2C PSer111 | phosphorylation down-regulates ⊣ | KIF2C | 23055517 | SIGNOR-199080 |
| PAK1 | phosphorylation up-regulates → | PGM1 PThr467 | phosphorylation up-regulates → | PGM1 | 15378030 | SIGNOR-127135 |
| PAK1 | phosphorylation up-regulates → | FXR1 PSer420 | phosphorylation up-regulates → | FXR1 | 20417602 | SIGNOR-273713 |
| PAK1 | phosphorylation up-regulates → | BAD PSer74 | phosphorylation down-regulates ⊣ | BAD | 22096607 | SIGNOR-177271 |
| PAK1 | phosphorylation up-regulates → | CTNNB1 PSer675 | phosphorylation up-regulates → | CTNNB1 | 21822311 | SIGNOR-175944 |
| PAK1 | phosphorylation up-regulates → | ARHGDIA PSer101 | phosphorylation down-regulates ⊣ | ARHGDIA | 15225553 | SIGNOR-126650 |
| PAK1 | phosphorylation up-regulates → | SYN1 PSer605 | phosphorylation up-regulates → | SYN1 | 12237306 | SIGNOR-250235 |
| PAK1 | phosphorylation up-regulates → | ARHGDIA PSer174 | phosphorylation down-regulates ⊣ | ARHGDIA | 15225553 | SIGNOR-126654 |
| PAK1 | phosphorylation up-regulates → | RPA1 PThr180 | phosphorylation up-regulates → | RPA1 | 33704464 | SIGNOR-279379 |
| PAK1 | phosphorylation up-regulates → | ILK PSer246 | phosphorylation up-regulates → | ILK | 17420447 | SIGNOR-154303 |
| PAK1 | phosphorylation up-regulates → | CTTN PSer405 | phosphorylation up-regulates → | CTTN | 20444238 | SIGNOR-165216 |
| PAK1 | phosphorylation up-regulates → | TBCB PSer65 | phosphorylation up-regulates → | TBCB | 15831477 | SIGNOR-135464 |
| PAK1 | phosphorylation up-regulates → | MORC2 PSer739 | phosphorylation up-regulates → | MORC2 | 25888627 | SIGNOR-273714 |
| PAK1 | phosphorylation up-regulates → | PREX2 PSer1107 | phosphorylation down-regulates ⊣ | PREX2 | 26438819 | SIGNOR-277181 |
| PAK1 | phosphorylation up-regulates → | BAD PSer99 | phosphorylation down-regulates ⊣ | BAD | 10611223 | SIGNOR-73533 |
| PAK1 | phosphorylation up-regulates → | NET1 PSer539 | phosphorylation down-regulates ⊣ | NET1 | 15684429 | SIGNOR-263018 |
| PAK1 | phosphorylation up-regulates → | CTBP1 PSer158 | phosphorylation down-regulates ⊣ | CTBP1 | 12872159 | SIGNOR-103943 |
| PAK1 | phosphorylation up-regulates → | ITGB3BP PSer28 | phosphorylation up-regulates → | ITGB3BP | 18521086 | SIGNOR-178795 |
| PAK1 | phosphorylation up-regulates → | AURKA PThr288 | phosphorylation up-regulates → | AURKA | 24867643 | SIGNOR-205110 |
| PAK1 | phosphorylation up-regulates → | SNAI1 PSer246 | phosphorylation up-regulates → | SNAI1 | 15833848 | SIGNOR-135605 |
| PAK1 | phosphorylation up-regulates → | PAK1 PSer57 | phosphorylation up-regulates → | PAK1 | 9032240 | SIGNOR-250219 |
| PAK1 | phosphorylation up-regulates → | VIM PSer56 | phosphorylation down-regulates ⊣ | VIM | 15766329 | SIGNOR-134520 |
| PAK1 | phosphorylation up-regulates → | STMN1 PSer38 | phosphorylation down-regulates ⊣ | STMN1 | 10913145 | SIGNOR-79955 |
| PAK1 | phosphorylation up-regulates → | FLNA PSer2152 | phosphorylation up-regulates → | FLNA | 12198493 | SIGNOR-92065 |
| PAK1 | phosphorylation up-regulates → | ATG5 PThr101 | phosphorylation up-regulates → | ATG5 | 36528756 | SIGNOR-275835 |
| PAK1 | phosphorylation up-regulates → | MORC2 PSer739 | phosphorylation up-regulates → | MORC2 | 23260667 | SIGNOR-278414 |
| PAK1 | phosphorylation up-regulates → | NLRP3 PThr659 | phosphorylation up-regulates → | NLRP3 | 33432150 | SIGNOR-277547 |
| PAK1 | phosphorylation up-regulates → | GNAZ PSer16 | phosphorylation up-regulates → | GNAZ | 9166747 | SIGNOR-48673 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PAK1 | phosphorylation → up-regulates activity | MYL12B | SIGNOR-280053 |
| PAK1 | phosphorylation![]() down-regulates | ARHGEF2 | SIGNOR-187573 |
| PAK1 | phosphorylation → down-regulates activity | SLC6A2 | SIGNOR-280054 |
| PAK1 | phosphorylation![]() down-regulates | KIF2C | SIGNOR-199084 |
| PAK1 | phosphorylation → up-regulates | CTTN | SIGNOR-169690 |
| PAK1 | phosphorylation → up-regulates activity | RPA1 | SIGNOR-279378 |
| PAK1 | phosphorylation![]() down-regulates | PGAM1 | SIGNOR-91598 |
| PAK1 | phosphorylation → up-regulates | RAF1 | SIGNOR-180808 |
| PAK1 | phosphorylation → up-regulates activity | MAP2K1 | SIGNOR-236002 |
| PAK1 | phosphorylation → up-regulates activity | LIMK1 | SIGNOR-72142 |
| PAK1 | phosphorylation → up-regulates activity | MID1 | SIGNOR-279307 |
| PAK1 | phosphorylation![]() down-regulates | BAD | SIGNOR-73529 |
| PAK1 | phosphorylation![]() down-regulates | DYNLL1 | SIGNOR-159995 |
| PAK1 | phosphorylation → unknown | PXN | SIGNOR-146842 |
| PAK1 | phosphorylation![]() down-regulates | NF2 | SIGNOR-159764 |
| PAK1 | phosphorylation → up-regulates | ILK | SIGNOR-154307 |
| PAK1 | phosphorylation → up-regulates | ARPC1B | SIGNOR-121642 |
| PAK1 | phosphorylation → up-regulates activity | PAK1 | SIGNOR-250216 |
| PAK1 | phosphorylation → up-regulates | ELF3 | SIGNOR-154743 |
| PAK1 | phosphorylation → up-regulates activity | STIM1 | SIGNOR-279244 |
| PAK1 | phosphorylation → up-regulates | CTTN | SIGNOR-169694 |
| PAK1 | phosphorylation → down-regulates activity | SORT1 | SIGNOR-273718 |
| PAK1 | phosphorylation![]() down-regulates quantity by destabilization | PGAM2 | SIGNOR-280237 |
| PAK1 | phosphorylation → unknown | H3C1 | SIGNOR-91050 |
| PAK1 | phosphorylation → up-regulates | ARAF | SIGNOR-236342 |
| PAK1 | phosphorylation![]() down-regulates | STMN1 | SIGNOR-183503 |
| PAK1 | phosphorylation → down-regulates activity | SPEN | SIGNOR-278968 |
| PAK1 | phosphorylation![]() down-regulates | PGAM1 | SIGNOR-91594 |
| PAK1 | phosphorylation → down-regulates activity | NET1 | SIGNOR-263019 |
| PAK1 | phosphorylation → up-regulates quantity | RUFY3 | SIGNOR-279243 |
| PAK1 | phosphorylation → down-regulates activity | ATF2 | SIGNOR-279377 |
| PAK1 | phosphorylation → up-regulates | TBCB | SIGNOR-135460 |
| PAK1 | phosphorylation → down-regulates activity | HACE1 | SIGNOR-255537 |
| PAK1 | phosphorylation → up-regulates | ESR1 | SIGNOR-94206 |
| PAK1 | phosphorylation → down-regulates activity | NET1 | SIGNOR-263017 |
| PAK1 | phosphorylation → up-regulates activity | NLRP3 | SIGNOR-278967 |
| PAK1 | phosphorylation → up-regulates | PLK1 | SIGNOR-178353 |
| PAK1 | phosphorylation → up-regulates | PA2G4 | SIGNOR-160963 |
| PAK1 | phosphorylation → down-regulates activity | FOXO1 | SIGNOR-279242 |
| PAK1 | phosphorylation![]() down-regulates | STMN1 | SIGNOR-119483 |
| PAK1 | phosphorylation → up-regulates | RAF1 | SIGNOR-180812 |
| PAK1 | phosphorylation → up-regulates activity | MAP3K1 | SIGNOR-236006 |
| PAK1 | phosphorylation → up-regulates | CTTN | SIGNOR-165220 |
| PAK1 | phosphorylation![]() down-regulates | KIF2C | SIGNOR-199080 |
| PAK1 | phosphorylation → up-regulates activity | AJUBA | SIGNOR-278449 |
| PAK1 | phosphorylation → up-regulates | PGM1 | SIGNOR-127135 |
| PAK1 | phosphorylation → up-regulates activity | FXR1 | SIGNOR-273713 |
| PAK1 | phosphorylation![]() down-regulates | BAD | SIGNOR-177271 |
| PAK1 | phosphorylation → up-regulates | CTNNB1 | SIGNOR-175944 |
| PAK1 | phosphorylation![]() down-regulates | ARHGDIA | SIGNOR-126650 |
| PAK1 | phosphorylation → up-regulates activity | SYN1 | SIGNOR-250235 |
| PAK1 | phosphorylation![]() down-regulates | ARHGDIA | SIGNOR-126654 |
| PAK1 | phosphorylation![]() down-regulates | WEE1 | SIGNOR-123528 |
| PAK1 | phosphorylation → up-regulates activity | RPA1 | SIGNOR-279379 |
| PAK1 | phosphorylation → up-regulates | ILK | SIGNOR-154303 |
| PAK1 | phosphorylation → up-regulates | CTTN | SIGNOR-165216 |
| PAK1 | phosphorylation → up-regulates | TBCB | SIGNOR-135464 |
| PAK1 | phosphorylation → up-regulates activity | MORC2 | SIGNOR-273714 |
| PAK1 | phosphorylation → down-regulates activity | PREX2 | SIGNOR-277181 |
| PAK1 | phosphorylation![]() down-regulates | BAD | SIGNOR-73533 |
| PAK1 | phosphorylation → down-regulates activity | NET1 | SIGNOR-263018 |
| PAK1 | phosphorylation → up-regulates activity | MEK1/2 | SIGNOR-244924 |
| PAK1 | phosphorylation![]() down-regulates | PGAM | SIGNOR-270283 |
| PAK1 | phosphorylation → down-regulates activity | CTBP1 | SIGNOR-103943 |
| PAK1 | phosphorylation → up-regulates | ITGB3BP | SIGNOR-178795 |
| PAK1 | phosphorylation → up-regulates | AURKA | SIGNOR-205110 |
| PAK1 | phosphorylation → down-regulates activity | MYLK | SIGNOR-250317 |
| PAK1 | phosphorylation → unknown | Histone H3 | SIGNOR-265363 |
| PAK1 | phosphorylation → up-regulates | SNAI1 | SIGNOR-135605 |
| PAK1 | phosphorylation → up-regulates activity | PAK1 | SIGNOR-250219 |
| PAK1 | phosphorylation → unknown | VIM | SIGNOR-134520 |
| PAK1 | phosphorylation![]() down-regulates | STMN1 | SIGNOR-79955 |
| PAK1 | phosphorylation → up-regulates | FLNA | SIGNOR-92065 |
| PAK1 | phosphorylation → down-regulates activity | BCL6 | SIGNOR-253930 |
| PAK1 | phosphorylation → up-regulates quantity by stabilization | ATG5 | SIGNOR-275835 |
| PAK1 | phosphorylation → up-regulates activity | MORC2 | SIGNOR-278414 |
| PAK1 | phosphorylation → up-regulates activity | NLRP3 | SIGNOR-277547 |
| PAK1 | phosphorylation → up-regulates | GNAZ | SIGNOR-48673 |