Entity Details

Name PPM1A_Ser199
ID Q13153
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPM1APAK1Ser199PRPEHTKsVYTRSVIdephosphorylation
down-regulates activity		18586681SIGNOR-248492
PAK1PAK1Ser199PRPEHTKsVYTRSVIphosphorylation
up-regulates activity		9032240SIGNOR-250216
PPP2CAPAK1Ser199PRPEHTKsVYTRSVIdephosphorylation
down-regulates activity		18586681SIGNOR-248642
PPP2CBPAK1Ser199PRPEHTKsVYTRSVIdephosphorylation
down-regulates activity		18586681SIGNOR-248599
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPM1Adephosphorylation
down-regulates
⊣
PAK1
PSer199		dephosphorylation
up-regulates
→		PAK118586681SIGNOR-248492
PAK1phosphorylation
up-regulates
→
PAK1
PSer199		phosphorylation
up-regulates
→		PAK19032240SIGNOR-250216
PPP2CAdephosphorylation
down-regulates
⊣
PAK1
PSer199		dephosphorylation
up-regulates
→		PAK118586681SIGNOR-248642
PPP2CBdephosphorylation
down-regulates
⊣
PAK1
PSer199		dephosphorylation
up-regulates
→		PAK118586681SIGNOR-248599
Regulator Mechanism/Effect Target SIGNOR-ID
PPM1Adephosphorylation
→
down-regulates activity 		PAK1SIGNOR-248492
PAK1phosphorylation
→
up-regulates activity 		PAK1SIGNOR-250216
PPP2CAdephosphorylation
→
down-regulates activity 		PAK1SIGNOR-248642
PPP2CBdephosphorylation
→
down-regulates activity 		PAK1SIGNOR-248599