Entity Details

Name PPP2CA_Ser57
ID Q13153
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPP2CAPAK1Ser57KKDRFYRsILPGDKTdephosphorylation
down-regulates activity		18586681SIGNOR-248641
PPM1EPAK1Ser57KKDRFYRsILPGDKTdephosphorylation
down-regulates activity		11864573SIGNOR-248760
PPM1FPAK1Ser57KKDRFYRsILPGDKTdephosphorylation
down-regulates activity		11864573SIGNOR-248530
PAK1PAK1Ser57KKDRFYRsILPGDKTphosphorylation
up-regulates activity		9032240SIGNOR-250219
PPM1APAK1Ser57KKDRFYRsILPGDKTdephosphorylation
down-regulates activity		18586681SIGNOR-248493
PPP2CBPAK1Ser57KKDRFYRsILPGDKTdephosphorylation
down-regulates activity		18586681SIGNOR-248598
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPP2CAdephosphorylation
down-regulates
⊣
PAK1
PSer57		dephosphorylation
up-regulates
→		PAK118586681SIGNOR-248641
PPM1Edephosphorylation
down-regulates
⊣
PAK1
PSer57		dephosphorylation
up-regulates
→		PAK111864573SIGNOR-248760
PPM1Fdephosphorylation
down-regulates
⊣
PAK1
PSer57		dephosphorylation
up-regulates
→		PAK111864573SIGNOR-248530
PAK1phosphorylation
up-regulates
→
PAK1
PSer57		phosphorylation
up-regulates
→		PAK19032240SIGNOR-250219
PPM1Adephosphorylation
down-regulates
⊣
PAK1
PSer57		dephosphorylation
up-regulates
→		PAK118586681SIGNOR-248493
PPP2CBdephosphorylation
down-regulates
⊣
PAK1
PSer57		dephosphorylation
up-regulates
→		PAK118586681SIGNOR-248598
Regulator Mechanism/Effect Target SIGNOR-ID
PPP2CAdephosphorylation
→
down-regulates activity 		PAK1SIGNOR-248641
PPM1Edephosphorylation
→
down-regulates activity 		PAK1SIGNOR-248760
PPM1Fdephosphorylation
→
down-regulates activity 		PAK1SIGNOR-248530
PAK1phosphorylation
→
up-regulates activity 		PAK1SIGNOR-250219
PPM1Adephosphorylation
→
down-regulates activity 		PAK1SIGNOR-248493
PPP2CBdephosphorylation
→
down-regulates activity 		PAK1SIGNOR-248598