Entity Details

Name MAP2K5
ID Q13163
Role kinase
Enzymatic Domains
PB1 18-109
PROSITE-ProRule
Protein kinase 166-409
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAP2K5MAPK7–phosphorylation
up-regulates		11782488SIGNOR-113770
MAP2K5MAPK7–phosphorylation
up-regulates		12912994SIGNOR-104631
MAP2K5MAPK7Thr219AEHQYFMtEYVATRWphosphorylation
up-regulates activity		20667468SIGNOR-259824
MAP2K5MAPK7Tyr221HQYFMTEyVATRWYRphosphorylation
up-regulates activity		20667468SIGNOR-259825
MAP2K5MAPK7–phosphorylation
up-regulates activity		23612709SIGNOR-255453
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAP2K5phosphorylation
up-regulates
→
MAPK7
PThr219		phosphorylation
up-regulates
→		MAPK720667468SIGNOR-259824
MAP2K5phosphorylation
up-regulates
→
MAPK7
PTyr221		phosphorylation
up-regulates
→		MAPK720667468SIGNOR-259825
Regulator Mechanism/Effect Target SIGNOR-ID
MAP2K5phosphorylation
→
up-regulates 		MAPK7SIGNOR-113770
MAP2K5phosphorylation
→
up-regulates 		MAPK7SIGNOR-104631
MAP2K5phosphorylation
→
up-regulates activity 		MAPK7SIGNOR-259824
MAP2K5phosphorylation
→
up-regulates activity 		MAPK7SIGNOR-259825
MAP2K5phosphorylation
→
up-regulates activity 		MAPK7SIGNOR-255453