Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAPK7	MAP2K5	Ser149 View in OncoXplorer	SNSLKKSsAELKKIL	phosphorylation up-regulates	12628002	SIGNOR-99139
MAPK7	MAP2K5	Ser129	VNTRAGPsQHSSPAV	phosphorylation up-regulates	12628002	SIGNOR-99127
MAPK7	MAP2K5	Ser142	AVSDSLPsNSLKKSS	phosphorylation up-regulates	12628002	SIGNOR-99135
MAP3K3	MAP2K5	–		phosphorylation up-regulates	12912994	SIGNOR-104637
MAPK7	MAP2K5	Ser137	QHSSPAVsDSLPSNS	phosphorylation up-regulates	12628002	SIGNOR-99131
GHR	MAP2K5	–		phosphorylation up-regulates activity	23612709	SIGNOR-255452
MAP3K2	MAP2K5	–		phosphorylation up-regulates	12912994	SIGNOR-104634

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAPK7	phosphorylation up-regulates →	MAP2K5 PSer149	phosphorylation up-regulates →	MAP2K5	12628002	SIGNOR-99139
MAPK7	phosphorylation up-regulates →	MAP2K5 PSer129	phosphorylation up-regulates →	MAP2K5	12628002	SIGNOR-99127
MAPK7	phosphorylation up-regulates →	MAP2K5 PSer142	phosphorylation up-regulates →	MAP2K5	12628002	SIGNOR-99135
MAPK7	phosphorylation up-regulates →	MAP2K5 PSer137	phosphorylation up-regulates →	MAP2K5	12628002	SIGNOR-99131

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAPK7	phosphorylation → up-regulates	MAP2K5	SIGNOR-99139
MAPK7	phosphorylation → up-regulates	MAP2K5	SIGNOR-99127
MAPK7	phosphorylation → up-regulates	MAP2K5	SIGNOR-99135
MAP3K3	phosphorylation → up-regulates	MAP2K5	SIGNOR-104637
MAPK7	phosphorylation → up-regulates	MAP2K5	SIGNOR-99131
GHR	phosphorylation → up-regulates activity	MAP2K5	SIGNOR-255452
MAP3K2	phosphorylation → up-regulates	MAP2K5	SIGNOR-104634