| Name | MAPK7 |
| ID | Q13164 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 55-347 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK7 | SGK1 | Ser78 | ANPSPPPsPSQQINL | phosphorylation up-regulates | 11254654 | SIGNOR-105728 |
| MAPK7 | CHEK1 | – | phosphorylation up-regulates activity | 30804322 | SIGNOR-280028 | |
| MAPK7 | ETS1 | Thr38 | CADVPLLtPSSKEMM | phosphorylation up-regulates | 12048211 | SIGNOR-88666 |
| MAPK7 | GJA1 | Ser255 | HATSGALsPAKDCGS | phosphorylation down-regulates activity | 12637502 | SIGNOR-250115 |
| MAPK7 | PML | – | phosphorylation down-regulates | 20832753 | SIGNOR-167947 | |
| MAPK7 | PML | Ser403 | AAVSKKAsPEAASTP | phosphorylation down-regulates activity | 23730625 | SIGNOR-279075 |
| MAPK7 | PML | Thr409 | ASPEAAStPRDPIDV | phosphorylation down-regulates activity | 23730625 | SIGNOR-279074 |
| MAPK7 | NR4A2 | – | phosphorylation up-regulates activity | 17020917 | SIGNOR-279215 | |
| MAPK7 | RPS6KA3 | – | phosphorylation up-regulates activity | 16626623 | SIGNOR-279216 | |
| MAPK7 | MEF2A | Ser355 | SALQGFNsPGMLSLG | phosphorylation up-regulates | 10849446 | SIGNOR-236587 |
| MAPK7 | MEF2A | Thr312 | QATQPLAtPVVSVTT | phosphorylation up-regulates | 10849446 | SIGNOR-236583 |
| MAPK7 | MEF2A | Thr319 | TPVVSVTtPSLPPQG | phosphorylation up-regulates | 10849446 | SIGNOR-236579 |
| MAPK7 | PTK2 | Tyr397 | SVSETDDyAEIIDEE | phosphorylation up-regulates activity | 33981002 | SIGNOR-279304 |
| MAPK7 | PTK2 | Ser910 | KLQPQEIsPPPTANL | phosphorylation up-regulates quantity | 32144580 | SIGNOR-279305 |
| MAPK7 | MEF2C | Ser387 | LSLPSTQsLNIKSEP | phosphorylation up-regulates | 9384584 | SIGNOR-53545 |
| MAPK7 | MAP2K5 | Ser129 | VNTRAGPsQHSSPAV | phosphorylation up-regulates | 12628002 | SIGNOR-99127 |
| MAPK7 | MAP2K5 | Ser137 | QHSSPAVsDSLPSNS | phosphorylation up-regulates | 12628002 | SIGNOR-99131 |
| MAPK7 | MAP2K5 | Ser142 | AVSDSLPsNSLKKSS | phosphorylation up-regulates | 12628002 | SIGNOR-99135 |
| MAPK7 | MAP2K5 | Ser149 | SNSLKKSsAELKKIL | phosphorylation up-regulates | 12628002 | SIGNOR-99139 |
| MAPK7 | MAPK7 | Ser567 | VLSDNDRsLLERWTR | phosphorylation up-regulates activity | 20667468 | SIGNOR-259823 |
| MAPK7 | MAPK7 | Ser731 | DPLPPVFsGTPKGSG | phosphorylation up-regulates activity | 20667468 | SIGNOR-259821 |
| MAPK7 | MAPK7 | Ser803 | QREIQMDsPMLLADL | phosphorylation up-regulates activity | 20667468 | SIGNOR-259826 |
| MAPK7 | MAPK7 | Thr733 | LPPVFSGtPKGSGAG | phosphorylation up-regulates activity | 20667468 | SIGNOR-259822 |
| MAPK7 | MEF2D | Ser180 | LTDPRLLsPQQPALQ | phosphorylation up-regulates | 10849446 | SIGNOR-236041 |
| MAPK7 | NEUROG1 | – | phosphorylation up-regulates activity | 19365559 | SIGNOR-278364 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK7 | phosphorylation up-regulates → | SGK1 PSer78 | phosphorylation up-regulates → | SGK1 | 11254654 | SIGNOR-105728 |
| MAPK7 | phosphorylation up-regulates → | ETS1 PThr38 | phosphorylation up-regulates → | ETS1 | 12048211 | SIGNOR-88666 |
| MAPK7 | phosphorylation up-regulates → | GJA1 PSer255 | phosphorylation down-regulates ⊣ | GJA1 | 12637502 | SIGNOR-250115 |
| MAPK7 | phosphorylation up-regulates → | PML PSer403 | phosphorylation down-regulates ⊣ | PML | 23730625 | SIGNOR-279075 |
| MAPK7 | phosphorylation up-regulates → | PML PThr409 | phosphorylation down-regulates ⊣ | PML | 23730625 | SIGNOR-279074 |
| MAPK7 | phosphorylation up-regulates → | MEF2A PSer355 | phosphorylation up-regulates → | MEF2A | 10849446 | SIGNOR-236587 |
| MAPK7 | phosphorylation up-regulates → | MEF2A PThr312 | phosphorylation up-regulates → | MEF2A | 10849446 | SIGNOR-236583 |
| MAPK7 | phosphorylation up-regulates → | MEF2A PThr319 | phosphorylation up-regulates → | MEF2A | 10849446 | SIGNOR-236579 |
| MAPK7 | phosphorylation up-regulates → | PTK2 PTyr397 | phosphorylation up-regulates → | PTK2 | 33981002 | SIGNOR-279304 |
| MAPK7 | phosphorylation up-regulates → | PTK2 PSer910 | phosphorylation up-regulates → | PTK2 | 32144580 | SIGNOR-279305 |
| MAPK7 | phosphorylation up-regulates → | MEF2C PSer387 | phosphorylation up-regulates → | MEF2C | 9384584 | SIGNOR-53545 |
| MAPK7 | phosphorylation up-regulates → | MAP2K5 PSer129 | phosphorylation up-regulates → | MAP2K5 | 12628002 | SIGNOR-99127 |
| MAPK7 | phosphorylation up-regulates → | MAP2K5 PSer137 | phosphorylation up-regulates → | MAP2K5 | 12628002 | SIGNOR-99131 |
| MAPK7 | phosphorylation up-regulates → | MAP2K5 PSer142 | phosphorylation up-regulates → | MAP2K5 | 12628002 | SIGNOR-99135 |
| MAPK7 | phosphorylation up-regulates → | MAP2K5 PSer149 | phosphorylation up-regulates → | MAP2K5 | 12628002 | SIGNOR-99139 |
| MAPK7 | phosphorylation up-regulates → | MAPK7 PSer567 | phosphorylation up-regulates → | MAPK7 | 20667468 | SIGNOR-259823 |
| MAPK7 | phosphorylation up-regulates → | MAPK7 PSer731 | phosphorylation up-regulates → | MAPK7 | 20667468 | SIGNOR-259821 |
| MAPK7 | phosphorylation up-regulates → | MAPK7 PSer803 | phosphorylation up-regulates → | MAPK7 | 20667468 | SIGNOR-259826 |
| MAPK7 | phosphorylation up-regulates → | MAPK7 PThr733 | phosphorylation up-regulates → | MAPK7 | 20667468 | SIGNOR-259822 |
| MAPK7 | phosphorylation up-regulates → | MEF2D PSer180 | phosphorylation up-regulates → | MEF2D | 10849446 | SIGNOR-236041 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK7 | phosphorylation → up-regulates | SGK1 | SIGNOR-105728 |
| MAPK7 | phosphorylation → up-regulates activity | CHEK1 | SIGNOR-280028 |
| MAPK7 | phosphorylation → up-regulates | ETS1 | SIGNOR-88666 |
| MAPK7 | phosphorylation → down-regulates activity | GJA1 | SIGNOR-250115 |
| MAPK7 | phosphorylation down-regulates | PML | SIGNOR-167947 |
| MAPK7 | phosphorylation → down-regulates activity | PML | SIGNOR-279075 |
| MAPK7 | phosphorylation → down-regulates activity | PML | SIGNOR-279074 |
| MAPK7 | phosphorylation → up-regulates activity | NR4A2 | SIGNOR-279215 |
| MAPK7 | phosphorylation → up-regulates activity | RPS6KA3 | SIGNOR-279216 |
| MAPK7 | phosphorylation → up-regulates | MEF2A | SIGNOR-236587 |
| MAPK7 | phosphorylation → up-regulates | MEF2A | SIGNOR-236583 |
| MAPK7 | phosphorylation → up-regulates | MEF2A | SIGNOR-236579 |
| MAPK7 | phosphorylation → up-regulates activity | PTK2 | SIGNOR-279304 |
| MAPK7 | phosphorylation → up-regulates quantity | PTK2 | SIGNOR-279305 |
| MAPK7 | phosphorylation → up-regulates | MEF2C | SIGNOR-53545 |
| MAPK7 | phosphorylation → up-regulates | MAP2K5 | SIGNOR-99127 |
| MAPK7 | phosphorylation → up-regulates | MAP2K5 | SIGNOR-99131 |
| MAPK7 | phosphorylation → up-regulates | MAP2K5 | SIGNOR-99135 |
| MAPK7 | phosphorylation → up-regulates | MAP2K5 | SIGNOR-99139 |
| MAPK7 | phosphorylation → up-regulates activity | MAPK7 | SIGNOR-259823 |
| MAPK7 | phosphorylation → up-regulates activity | MAPK7 | SIGNOR-259821 |
| MAPK7 | phosphorylation → up-regulates activity | MAPK7 | SIGNOR-259826 |
| MAPK7 | phosphorylation → up-regulates activity | MAPK7 | SIGNOR-259822 |
| MAPK7 | phosphorylation → up-regulates | MEF2D | SIGNOR-236041 |
| MAPK7 | phosphorylation → up-regulates activity | NEUROG1 | SIGNOR-278364 |