Entity Details

Name SLA
ID Q13239
Role substrate
Enzymatic Domains
SH3 22-82
PROSITE-ProRule
SH2 84-175
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
KITSLATyr273SFFSSPPyFEDphosphorylation
down-regulates activity		24284075SIGNOR-263142
KITSLATyr120SETKKGFySLSVRHRphosphorylation
down-regulates activity		24284075SIGNOR-263140
KITSLATyr258KKSISLMyGGSKRKSphosphorylation
down-regulates activity		24284075SIGNOR-263141
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
KITphosphorylation
up-regulates
→
SLA
PTyr273		phosphorylation
down-regulates
⊣		SLA24284075SIGNOR-263142
KITphosphorylation
up-regulates
→
SLA
PTyr120		phosphorylation
down-regulates
⊣		SLA24284075SIGNOR-263140
KITphosphorylation
up-regulates
→
SLA
PTyr258		phosphorylation
down-regulates
⊣		SLA24284075SIGNOR-263141
Regulator Mechanism/Effect Target SIGNOR-ID
KITphosphorylation
→
down-regulates activity 		SLASIGNOR-263142
KITphosphorylation
→
down-regulates activity 		SLASIGNOR-263140
KITphosphorylation
→
down-regulates activity 		SLASIGNOR-263141