Entity Details

Name AKT1_Ser72
ID Q13309
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PIM1SKP2Ser72PPRKRLKsKGSDKDFphosphorylation
up-regulates activity		20663873SIGNOR-259819
AKT1SKP2Ser72PPRKRLKsKGSDKDFphosphorylation
down-regulates activity		19270695SIGNOR-278274
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PIM1phosphorylation
up-regulates
→
SKP2
PSer72		phosphorylation
up-regulates
→		SKP220663873SIGNOR-259819
AKT1phosphorylation
up-regulates
→
SKP2
PSer72		phosphorylation
down-regulates
⊣		SKP219270695SIGNOR-278274
Regulator Mechanism/Effect Target SIGNOR-ID
PIM1phosphorylation
→
up-regulates activity 		SKP2SIGNOR-259819
AKT1phosphorylation
→
down-regulates activity 		SKP2SIGNOR-278274