Entity Details

Name CDC14B_Ser64
ID Q13309
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK2SKP2Ser64SNLGHPEsPPRKRLKphosphorylation
up-regulates quantity by stabilization		18239684SIGNOR-249173
PIM1SKP2Ser64SNLGHPEsPPRKRLKphosphorylation
up-regulates activity		20663873SIGNOR-259818
CDC14BSKP2Ser64SNLGHPEsPPRKRLKdephosphorylation
down-regulates quantity by destabilization		18239684SIGNOR-248333
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK2phosphorylation
up-regulates
→
SKP2
PSer64		phosphorylation
up-regulates
→		SKP218239684SIGNOR-249173
PIM1phosphorylation
up-regulates
→
SKP2
PSer64		phosphorylation
up-regulates
→		SKP220663873SIGNOR-259818
CDC14Bdephosphorylation
down-regulates
⊣
SKP2
PSer64		dephosphorylation
up-regulates
→		SKP218239684SIGNOR-248333
Regulator Mechanism/Effect Target SIGNOR-ID
CDK2phosphorylation
→
up-regulates quantity by stabilization 		SKP2SIGNOR-249173
PIM1phosphorylation
→
up-regulates activity 		SKP2SIGNOR-259818
CDC14Bdephosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		SKP2SIGNOR-248333