| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | GRB10 | Ser418 | QQRKALLsPFSTPVR | phosphorylation unknown | 15952796 | SIGNOR-249406 |
| MAPK1 | GRB10 | Ser418 | QQRKALLsPFSTPVR | phosphorylation unknown | 15952796 | SIGNOR-249405 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | GRB10 PSer418 | phosphorylation down-regulates ⊣ | GRB10 | 15952796 | SIGNOR-249406 |
| MAPK1 | phosphorylation up-regulates → | GRB10 PSer418 | phosphorylation down-regulates ⊣ | GRB10 | 15952796 | SIGNOR-249405 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation → unknown | GRB10 | SIGNOR-249406 |
| MAPK1 | phosphorylation → unknown | GRB10 | SIGNOR-249405 |
