| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2R5C | TP53 | Thr55 | DDIEQWFtEDPGPDE | dephosphorylation up-regulates quantity by stabilization | 17245430 | SIGNOR-268154 |
| PPP2R5C | ATF1 | Ser36 | AQQVSSLsESEESQD | dephosphorylation up-regulates | 20730097 | SIGNOR-167560 |
| PPP2R5C | ATF1 | Ser38 | QVSSLSEsEESQDSS | dephosphorylation up-regulates | 20730097 | SIGNOR-167564 |
| PPP2R5C | ATF1 | Ser41 | SLSESEEsQDSSDSI | dephosphorylation up-regulates | 20730097 | SIGNOR-167568 |
| PPP2R5C | ATF1 | Ser44 | ESEESQDsSDSIGSS | dephosphorylation up-regulates | 20730097 | SIGNOR-167572 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2R5C | dephosphorylation down-regulates ⊣ | TP53 PThr55 | dephosphorylation down-regulates ⊣ | TP53 | 17245430 | SIGNOR-268154 |
| PPP2R5C | dephosphorylation down-regulates ⊣ | ATF1 PSer36 | dephosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167560 |
| PPP2R5C | dephosphorylation down-regulates ⊣ | ATF1 PSer38 | dephosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167564 |
| PPP2R5C | dephosphorylation down-regulates ⊣ | ATF1 PSer41 | dephosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167568 |
| PPP2R5C | dephosphorylation down-regulates ⊣ | ATF1 PSer44 | dephosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167572 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2R5C | dephosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-268154 |
| PPP2R5C | dephosphorylation → up-regulates | ATF1 | SIGNOR-167560 |
| PPP2R5C | dephosphorylation → up-regulates | ATF1 | SIGNOR-167564 |
| PPP2R5C | dephosphorylation → up-regulates | ATF1 | SIGNOR-167568 |
| PPP2R5C | dephosphorylation → up-regulates | ATF1 | SIGNOR-167572 |
