| Name | PLD1 |
| ID | Q13393 |
| Role | substrate |
| Enzymatic Domains |
PX 81-212 PROSITE-ProRule
PH 219-328
PLD phosphodiesterase 1 459-486 PROSITE-ProRule
PLD phosphodiesterase 2 891-918 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | PLD1 | Thr147 | PIPTRRHtFRRQNVR | phosphorylation up-regulates | 10441128 | SIGNOR-69938 |
| PRKAA2 | PLD1 | Ser505 | GSVKRVTsGPSLGSL | phosphorylation up-regulates | 20231899 | SIGNOR-164293 |
| AMPK | PLD1 | Ser505 | GSVKRVTsGPSLGSL | phosphorylation up-regulates | 20231899 | SIGNOR-216643 |
| PRKCA | PLD1 | Ser2 | sLKNEPRV | phosphorylation up-regulates | 10441128 | SIGNOR-69930 |
| PRKCA | PLD1 | Ser561 | PRKFSKFsLYKQLHR | phosphorylation up-regulates | 10441128 | SIGNOR-69934 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | PLD1 PThr147 | phosphorylation up-regulates → | PLD1 | 10441128 | SIGNOR-69938 |
| PRKAA2 | phosphorylation up-regulates → | PLD1 PSer505 | phosphorylation up-regulates → | PLD1 | 20231899 | SIGNOR-164293 |
| AMPK | phosphorylation up-regulates → | PLD1 PSer505 | phosphorylation up-regulates → | PLD1 | 20231899 | SIGNOR-216643 |
| PRKCA | phosphorylation up-regulates → | PLD1 PSer2 | phosphorylation up-regulates → | PLD1 | 10441128 | SIGNOR-69930 |
| PRKCA | phosphorylation up-regulates → | PLD1 PSer561 | phosphorylation up-regulates → | PLD1 | 10441128 | SIGNOR-69934 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation → up-regulates | PLD1 | SIGNOR-69938 |
| PRKAA2 | phosphorylation → up-regulates | PLD1 | SIGNOR-164293 |
| AMPK | phosphorylation → up-regulates | PLD1 | SIGNOR-216643 |
| PRKCA | phosphorylation → up-regulates | PLD1 | SIGNOR-69930 |
| PRKCA | phosphorylation → up-regulates | PLD1 | SIGNOR-69934 |