4.0
Summary
| Name |  PLD1View Modifications |
| Full Name | Phospholipase D1 |
| Synonyms | PLD 1, hPLD1, Choline phosphatase 1, Phosphatidylcholine-hydrolyzing phospholipase D1 |
| Primary ID | Q13393 |
| Links |  -  -  |
| Type | protein |
| Relations | 8 |
| Function | Function as phospholipase selective for phosphatidylcholine (PubMed:8530346, PubMed:9582313). Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKCA | up-regulates 
phosphorylation
|
PLD1 | 0.714 |
| Publications: | 3 | Organism: | Homo Sapiens | |
| Tissue: | Brain | |||
| + | PRKAA2 | up-regulates
phosphorylation
|
PLD1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Muscle, Skeletal Muscle | |||
| + | AMPK | up-regulates
phosphorylation
|
PLD1 | 0.243 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Muscle, Skeletal Muscle | |||
| + | PLD1 | up-regulates
chemical modification
|
phosphatidic acid | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RHOA | up-regulates
binding
|
PLD1 | 0.697 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RHEB | up-regulates
binding
|
PLD1 | 0.539 |
| Publications: | 1 | Organism: | Homo Sapiens | |