Entity Details

Name PPP3CB_Ser221
ID Q13469
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPP3CBNFATC2Ser221PRTSPIMsPRTSLAEdephosphorylation
up-regulates activity		11030334SIGNOR-248373
PPP3CANFATC2Ser221PRTSPIMsPRTSLAEdephosphorylation
up-regulates activity		11030334SIGNOR-248687
CalcineurinNFATC2Ser221PRTSPIMsPRTSLAEdephosphorylation
up-regulates activity		11030334SIGNOR-252331
PPP3CCNFATC2Ser221PRTSPIMsPRTSLAEdephosphorylation
up-regulates activity		11030334SIGNOR-248518
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPP3CBdephosphorylation
down-regulates
⊣
NFATC2
PSer221		dephosphorylation
down-regulates
⊣		NFATC211030334SIGNOR-248373
PPP3CAdephosphorylation
down-regulates
⊣
NFATC2
PSer221		dephosphorylation
down-regulates
⊣		NFATC211030334SIGNOR-248687
Calcineurindephosphorylation
down-regulates
⊣
NFATC2
PSer221		dephosphorylation
down-regulates
⊣		NFATC211030334SIGNOR-252331
PPP3CCdephosphorylation
down-regulates
⊣
NFATC2
PSer221		dephosphorylation
down-regulates
⊣		NFATC211030334SIGNOR-248518
Regulator Mechanism/Effect Target SIGNOR-ID
PPP3CBdephosphorylation
→
up-regulates activity 		NFATC2SIGNOR-248373
PPP3CAdephosphorylation
→
up-regulates activity 		NFATC2SIGNOR-248687
Calcineurindephosphorylation
→
up-regulates activity 		NFATC2SIGNOR-252331
PPP3CCdephosphorylation
→
up-regulates activity 		NFATC2SIGNOR-248518