| Name | ATR |
| ID | Q13535 |
| Role | kinase |
| Enzymatic Domains |
FAT 1640-2185 PROSITE-ProRule
PI3K/PI4K catalytic 2296-2604 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATR | RPA2 | Ser33 | GFGSPAPsQAEKKSR | phosphorylation unknown | 19843584 | SIGNOR-188666 |
| ATR | CHEK2 | Thr68 | SSLETVStQELYSIP | phosphorylation up-regulates activity | 10973490 | SIGNOR-81442 |
| ATR | BRCA1 | Ser1457 | SEKAVLTsQKSSEYP | phosphorylation up-regulates activity | 11278964 | SIGNOR-106440 |
| ATR | KIFC1 | Ser26 | RPLIKAPsQLPLSGS | phosphorylation up-regulates quantity by stabilization | 33397932 | SIGNOR-277296 |
| ATR | CDC25A | – | phosphorylation down-regulates activity | 29054375 | SIGNOR-280183 | |
| ATR | XPA | Ser196 | RSLEVWGsQEALEEA | phosphorylation up-regulates | 23178497 | SIGNOR-199802 |
| ATR | ATRIP | Ser72 | TLASQALsQCPAAAR | phosphorylation up-regulates | 15451423 | SIGNOR-129473 |
| ATR | DBF4 | Thr449 | DDIRQNFtQLPLHKN | phosphorylation down-regulates | 22123827 | SIGNOR-177813 |
| ATR | RAD17 | Ser646 | ETWSLPLsQNSASEL | phosphorylation up-regulates activity | 11687627 | SIGNOR-111248 |
| ATR | POLH | Ser601 | EMDLAHNsQSMHASS | phosphorylation up-regulates | 21242293 | SIGNOR-171290 |
| ATR | ZDHHC13 | Ser8 | MEGPGLGsQCRNHSH | phosphorylation up-regulates activity | 28869973 | SIGNOR-273517 |
| ATR | XPA | Ser173 | VKKNPHHsQWGDMKL | phosphorylation up-regulates activity | 16540648 | SIGNOR-250584 |
| ATR | BRCA1 | Ser1143 | PMGSSHAsQVCSETP | phosphorylation up-regulates activity | 11114888 | SIGNOR-250581 |
| ATR | FANCI | – | phosphorylation up-regulates activity | 23723247 | SIGNOR-279320 | |
| ATR | XRCC3 | Ser225 | PFRCEFDsQASAPRA | phosphorylation up-regulates activity | 23438602 | SIGNOR-262666 |
| ATR | CHKA | – | phosphorylation up-regulates activity | 16085356 | SIGNOR-280184 | |
| ATR | PARP1 | Ser179 | FRPEYSAsQLKGFSL | phosphorylation down-regulates | 33811702 | SIGNOR-278506 |
| ATR | DCK | Ser74 | EFEELTMsQKNGGNV | phosphorylation up-regulates activity | 26620371 | SIGNOR-279494 |
| ATR | WRN | Ser1141 | PEKAYSSsQPVISAQ | phosphorylation down-regulates quantity | 26695548 | SIGNOR-278159 |
| ATR | ETV1 | – | phosphorylation up-regulates quantity by stabilization | 23284306 | SIGNOR-279355 | |
| ATR | CDC25C | Ser216 | SGLYRSPsMPENLNR | phosphorylation up-regulates activity | 28264028 | SIGNOR-279008 |
| ATR | KMT2A | Ser516 | VHPPLPIsQSPENES | phosphorylation up-regulates | 4709074 | SIGNOR-25151 |
| ATR | WRN | Ser1141 | PEKAYSSsQPVISAQ | phosphorylation down-regulates quantity by destabilization | 26695548 | SIGNOR-277187 |
| ATR | MCM6 | – | phosphorylation up-regulates | 21070963 | SIGNOR-169450 | |
| ATR | MCM2 | Ser108 | DVEELTAsQREAAER | phosphorylation unknown | 15210935 | SIGNOR-126363 |
| ATR | SMARCAL1 | Ser652 | RLKSDVLsQLPAKQR | phosphorylation down-regulates activity | 23873943 | SIGNOR-273516 |
| ATR | USP20 | – | phosphorylation down-regulates activity | 25355518 | SIGNOR-278393 | |
| ATR | USP28 | Ser67 | DERVKEPsQDTVATE | phosphorylation up-regulates activity | 31938050 | SIGNOR-275850 |
| ATR | NBN | Ser343 | TTPGPSLsQGVSVDE | phosphorylation up-regulates | 17526493 | SIGNOR-155214 |
| ATR | FANCD2 | Ser717 | KDGGPVTsQESGQKL | phosphorylation up-regulates | 16943440 | SIGNOR-149305 |
| ATR | CCAR2 | Thr454 | AAEAAPPtQEAQGET | phosphorylation up-regulates activity | 22735644 | SIGNOR-267662 |
| ATR | AKAP12 | Ser732 | TDGILAGsQEHDPGQ | phosphorylation up-regulates activity | 27683220 | SIGNOR-278292 |
| ATR | RAD17 | Ser656 | SASELPAsQPQPFSA | phosphorylation up-regulates activity | 11687627 | SIGNOR-111252 |
| ATR | BRCA1 | Ser1280 | QVILAKAsQEHHLSE | phosphorylation up-regulates activity | 11114888 | SIGNOR-250582 |
| ATR | ATRIP | Ser68 | EELDTLAsQALSQCP | phosphorylation up-regulates | 15451423 | SIGNOR-129469 |
| ATR | WDHD1 | Thr826 | KAAELTAtQVEEEEE | phosphorylation up-regulates activity | 26082189 | SIGNOR-262664 |
| ATR | SIAH1 | Ser19 | GTSKCPPsQRVPALT | phosphorylation down-regulates activity | 18536714 | SIGNOR-276167 |
| ATR | XPA | Ser196 | RSLEVWGsQEALEEA | phosphorylation up-regulates | 16540648 | SIGNOR-145190 |
| ATR | RBBP8 | Thr859 | WEVGFPStQTCMERG | phosphorylation up-regulates | 23273981 | SIGNOR-200245 |
| ATR | ATM | Ser1981 | SLAFEEGsQSTTISS | phosphorylation up-regulates activity | 17124492 | SIGNOR-150870 |
| ATR | BLM | – | phosphorylation up-regulates activity | 11916980 | SIGNOR-278978 | |
| ATR | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates quantity by stabilization | 11865061 | SIGNOR-115134 |
| ATR | USP20 | – | phosphorylation up-regulates quantity by stabilization | 25355518 | SIGNOR-272822 | |
| ATR | H2AX | Ser140 | GKKATQAsQEY | phosphorylation up-regulates activity | 27442013 | SIGNOR-279356 |
| ATR | CREB1 | Ser107 | SVDSVTDsQKRREIL | phosphorylation down-regulates | 15073328 | SIGNOR-124060 |
| ATR | DBF4 | Ser502 | FSTDNSGsQPKQKSD | phosphorylation down-regulates | 22123827 | SIGNOR-177805 |
| ATR | CHEK1 | Ser317 | ENVKYSSsQPEPRTG | phosphorylation up-regulates | 15775976 | SIGNOR-134712 |
| ATR | DBF4 | Ser539 | GLITINSsQEHLTVQ | phosphorylation down-regulates | 22123827 | SIGNOR-177809 |
| ATR | FANCD2 | Thr691 | YGLEEYDtQDGIAIN | phosphorylation up-regulates | 16943440 | SIGNOR-149309 |
| ATR | MCC | Ser120 | LRSELSQsQHEVNED | phosphorylation up-regulates activity | 21779472 | SIGNOR-273515 |
| ATR | E2F1 | Ser31 | ALRLLDSsQIVIISA | phosphorylation up-regulates quantity by stabilization | 11459832 | SIGNOR-109420 |
| ATR | FANCA | Ser1449 | AAPDADLsQEPHLF | phosphorylation up-regulates | 19109555 | SIGNOR-182953 |
| ATR | BRCA1 | Ser1423 | AVLEQHGsQPSNSYP | phosphorylation up-regulates activity | 11278964 | SIGNOR-106436 |
| ATR | BRCA1 | Ser1387 | EDCSGLSsQSDILTT | phosphorylation up-regulates activity | 11278964 | SIGNOR-106432 |
| ATR | PRKDC | Thr2609 | LTPMFVEtQASQGTL | phosphorylation up-regulates | 16908529 | SIGNOR-148722 |
| ATR | CHEK1 | Ser345 | LVQGISFsQPTCPDH | phosphorylation up-regulates | 15775976 | SIGNOR-134716 |
| ATR | PARP1 | Ser179 | FRPEYSAsQLKGFSL | phosphorylation down-regulates activity | 33811702 | SIGNOR-277551 |
| ATR | USP28 | Ser714 | ESSTNSSsQDYSTSQ | phosphorylation up-regulates activity | 31938050 | SIGNOR-275851 |
| ATR | MDM2 | Ser407 | SSSIIYSsQEDVKEF | phosphorylation down-regulates activity | 14654783 | SIGNOR-119546 |
| ATR | BRCA1 | Thr1394 | SQSDILTtQQRDTMQ | phosphorylation up-regulates activity | 11114888 | SIGNOR-250583 |
| ATR | BRCA1 | – | phosphorylation up-regulates | 23422745 | SIGNOR-201050 | |
| ATR | XPA | Ser196 | RSLEVWGsQEALEEA | phosphorylation up-regulates activity | 30327428 | SIGNOR-258985 |
| ATR | MCC | Ser118 | SELRSELsQSQHEVN | phosphorylation up-regulates activity | 21779472 | SIGNOR-273514 |
| ATR | MCM4 | – | phosphorylation up-regulates | 21070963 | SIGNOR-169412 | |
| ATR | UPF1 | – | phosphorylation up-regulates activity | 29192227 | SIGNOR-278911 | |
| ATR | PALB2 | – | phosphorylation up-regulates activity | 28089683 | SIGNOR-279588 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATR | phosphorylation up-regulates → | RPA2 PSer33 | phosphorylation down-regulates ⊣ | RPA2 | 19843584 | SIGNOR-188666 |
| ATR | phosphorylation up-regulates → | CHEK2 PThr68 | phosphorylation up-regulates → | CHEK2 | 10973490 | SIGNOR-81442 |
| ATR | phosphorylation up-regulates → | BRCA1 PSer1457 | phosphorylation up-regulates → | BRCA1 | 11278964 | SIGNOR-106440 |
| ATR | phosphorylation up-regulates → | KIFC1 PSer26 | phosphorylation up-regulates → | KIFC1 | 33397932 | SIGNOR-277296 |
| ATR | phosphorylation up-regulates → | XPA PSer196 | phosphorylation up-regulates → | XPA | 23178497 | SIGNOR-199802 |
| ATR | phosphorylation up-regulates → | ATRIP PSer72 | phosphorylation up-regulates → | ATRIP | 15451423 | SIGNOR-129473 |
| ATR | phosphorylation up-regulates → | DBF4 PThr449 | phosphorylation down-regulates ⊣ | DBF4 | 22123827 | SIGNOR-177813 |
| ATR | phosphorylation up-regulates → | RAD17 PSer646 | phosphorylation up-regulates → | RAD17 | 11687627 | SIGNOR-111248 |
| ATR | phosphorylation up-regulates → | POLH PSer601 | phosphorylation up-regulates → | POLH | 21242293 | SIGNOR-171290 |
| ATR | phosphorylation up-regulates → | ZDHHC13 PSer8 | phosphorylation up-regulates → | ZDHHC13 | 28869973 | SIGNOR-273517 |
| ATR | phosphorylation up-regulates → | XPA PSer173 | phosphorylation up-regulates → | XPA | 16540648 | SIGNOR-250584 |
| ATR | phosphorylation up-regulates → | BRCA1 PSer1143 | phosphorylation up-regulates → | BRCA1 | 11114888 | SIGNOR-250581 |
| ATR | phosphorylation up-regulates → | XRCC3 PSer225 | phosphorylation up-regulates → | XRCC3 | 23438602 | SIGNOR-262666 |
| ATR | phosphorylation up-regulates → | PARP1 PSer179 | phosphorylation down-regulates ⊣ | PARP1 | 33811702 | SIGNOR-278506 |
| ATR | phosphorylation up-regulates → | DCK PSer74 | phosphorylation up-regulates → | DCK | 26620371 | SIGNOR-279494 |
| ATR | phosphorylation up-regulates → | WRN PSer1141 | phosphorylation down-regulates ⊣ | WRN | 26695548 | SIGNOR-278159 |
| ATR | phosphorylation up-regulates → | CDC25C PSer216 | phosphorylation up-regulates → | CDC25C | 28264028 | SIGNOR-279008 |
| ATR | phosphorylation up-regulates → | KMT2A PSer516 | phosphorylation up-regulates → | KMT2A | 4709074 | SIGNOR-25151 |
| ATR | phosphorylation up-regulates → | WRN PSer1141 | phosphorylation down-regulates ⊣ | WRN | 26695548 | SIGNOR-277187 |
| ATR | phosphorylation up-regulates → | MCM2 PSer108 | phosphorylation down-regulates ⊣ | MCM2 | 15210935 | SIGNOR-126363 |
| ATR | phosphorylation up-regulates → | SMARCAL1 PSer652 | phosphorylation down-regulates ⊣ | SMARCAL1 | 23873943 | SIGNOR-273516 |
| ATR | phosphorylation up-regulates → | USP28 PSer67 | phosphorylation up-regulates → | USP28 | 31938050 | SIGNOR-275850 |
| ATR | phosphorylation up-regulates → | NBN PSer343 | phosphorylation up-regulates → | NBN | 17526493 | SIGNOR-155214 |
| ATR | phosphorylation up-regulates → | FANCD2 PSer717 | phosphorylation up-regulates → | FANCD2 | 16943440 | SIGNOR-149305 |
| ATR | phosphorylation up-regulates → | CCAR2 PThr454 | phosphorylation up-regulates → | CCAR2 | 22735644 | SIGNOR-267662 |
| ATR | phosphorylation up-regulates → | AKAP12 PSer732 | phosphorylation up-regulates → | AKAP12 | 27683220 | SIGNOR-278292 |
| ATR | phosphorylation up-regulates → | RAD17 PSer656 | phosphorylation up-regulates → | RAD17 | 11687627 | SIGNOR-111252 |
| ATR | phosphorylation up-regulates → | BRCA1 PSer1280 | phosphorylation up-regulates → | BRCA1 | 11114888 | SIGNOR-250582 |
| ATR | phosphorylation up-regulates → | ATRIP PSer68 | phosphorylation up-regulates → | ATRIP | 15451423 | SIGNOR-129469 |
| ATR | phosphorylation up-regulates → | WDHD1 PThr826 | phosphorylation up-regulates → | WDHD1 | 26082189 | SIGNOR-262664 |
| ATR | phosphorylation up-regulates → | SIAH1 PSer19 | phosphorylation down-regulates ⊣ | SIAH1 | 18536714 | SIGNOR-276167 |
| ATR | phosphorylation up-regulates → | XPA PSer196 | phosphorylation up-regulates → | XPA | 16540648 | SIGNOR-145190 |
| ATR | phosphorylation up-regulates → | RBBP8 PThr859 | phosphorylation up-regulates → | RBBP8 | 23273981 | SIGNOR-200245 |
| ATR | phosphorylation up-regulates → | ATM PSer1981 | phosphorylation up-regulates → | ATM | 17124492 | SIGNOR-150870 |
| ATR | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 11865061 | SIGNOR-115134 |
| ATR | phosphorylation up-regulates → | H2AX PSer140 | phosphorylation up-regulates → | H2AX | 27442013 | SIGNOR-279356 |
| ATR | phosphorylation up-regulates → | CREB1 PSer107 | phosphorylation down-regulates ⊣ | CREB1 | 15073328 | SIGNOR-124060 |
| ATR | phosphorylation up-regulates → | DBF4 PSer502 | phosphorylation down-regulates ⊣ | DBF4 | 22123827 | SIGNOR-177805 |
| ATR | phosphorylation up-regulates → | CHEK1 PSer317 | phosphorylation up-regulates → | CHEK1 | 15775976 | SIGNOR-134712 |
| ATR | phosphorylation up-regulates → | DBF4 PSer539 | phosphorylation down-regulates ⊣ | DBF4 | 22123827 | SIGNOR-177809 |
| ATR | phosphorylation up-regulates → | FANCD2 PThr691 | phosphorylation up-regulates → | FANCD2 | 16943440 | SIGNOR-149309 |
| ATR | phosphorylation up-regulates → | MCC PSer120 | phosphorylation up-regulates → | MCC | 21779472 | SIGNOR-273515 |
| ATR | phosphorylation up-regulates → | E2F1 PSer31 | phosphorylation up-regulates → | E2F1 | 11459832 | SIGNOR-109420 |
| ATR | phosphorylation up-regulates → | FANCA PSer1449 | phosphorylation up-regulates → | FANCA | 19109555 | SIGNOR-182953 |
| ATR | phosphorylation up-regulates → | BRCA1 PSer1423 | phosphorylation up-regulates → | BRCA1 | 11278964 | SIGNOR-106436 |
| ATR | phosphorylation up-regulates → | BRCA1 PSer1387 | phosphorylation up-regulates → | BRCA1 | 11278964 | SIGNOR-106432 |
| ATR | phosphorylation up-regulates → | PRKDC PThr2609 | phosphorylation up-regulates → | PRKDC | 16908529 | SIGNOR-148722 |
| ATR | phosphorylation up-regulates → | CHEK1 PSer345 | phosphorylation up-regulates → | CHEK1 | 15775976 | SIGNOR-134716 |
| ATR | phosphorylation up-regulates → | PARP1 PSer179 | phosphorylation down-regulates ⊣ | PARP1 | 33811702 | SIGNOR-277551 |
| ATR | phosphorylation up-regulates → | USP28 PSer714 | phosphorylation up-regulates → | USP28 | 31938050 | SIGNOR-275851 |
| ATR | phosphorylation up-regulates → | MDM2 PSer407 | phosphorylation down-regulates ⊣ | MDM2 | 14654783 | SIGNOR-119546 |
| ATR | phosphorylation up-regulates → | BRCA1 PThr1394 | phosphorylation up-regulates → | BRCA1 | 11114888 | SIGNOR-250583 |
| ATR | phosphorylation up-regulates → | XPA PSer196 | phosphorylation up-regulates → | XPA | 30327428 | SIGNOR-258985 |
| ATR | phosphorylation up-regulates → | MCC PSer118 | phosphorylation up-regulates → | MCC | 21779472 | SIGNOR-273514 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ATR | phosphorylation → unknown | RPA2 | SIGNOR-188666 |
| ATR | phosphorylation → up-regulates activity | CHEK2 | SIGNOR-81442 |
| ATR | phosphorylation → up-regulates activity | BRCA1 | SIGNOR-106440 |
| ATR | phosphorylation → up-regulates quantity by stabilization | KIFC1 | SIGNOR-277296 |
| ATR | phosphorylation → down-regulates activity | CDC25A | SIGNOR-280183 |
| ATR | phosphorylation → up-regulates | XPA | SIGNOR-199802 |
| ATR | phosphorylation → up-regulates | ATRIP | SIGNOR-129473 |
| ATR | phosphorylation down-regulates | DBF4 | SIGNOR-177813 |
| ATR | phosphorylation → up-regulates activity | RAD17 | SIGNOR-111248 |
| ATR | phosphorylation → up-regulates | POLH | SIGNOR-171290 |
| ATR | phosphorylation → up-regulates activity | ZDHHC13 | SIGNOR-273517 |
| ATR | phosphorylation → up-regulates activity | XPA | SIGNOR-250584 |
| ATR | phosphorylation → up-regulates activity | BRCA1 | SIGNOR-250581 |
| ATR | phosphorylation → up-regulates activity | FANCI | SIGNOR-279320 |
| ATR | phosphorylation → up-regulates activity | XRCC3 | SIGNOR-262666 |
| ATR | phosphorylation → up-regulates activity | CHKA | SIGNOR-280184 |
| ATR | phosphorylation down-regulates | PARP1 | SIGNOR-278506 |
| ATR | phosphorylation → up-regulates activity | DCK | SIGNOR-279494 |
| ATR | phosphorylation → down-regulates quantity | WRN | SIGNOR-278159 |
| ATR | phosphorylation → up-regulates quantity by stabilization | ETV1 | SIGNOR-279355 |
| ATR | phosphorylation → up-regulates activity | CDC25C | SIGNOR-279008 |
| ATR | phosphorylation → up-regulates | KMT2A | SIGNOR-25151 |
| ATR | phosphorylation down-regulates quantity by destabilization | WRN | SIGNOR-277187 |
| ATR | phosphorylation → up-regulates | MCM6 | SIGNOR-169450 |
| ATR | phosphorylation → unknown | MCM2 | SIGNOR-126363 |
| ATR | phosphorylation → down-regulates activity | SMARCAL1 | SIGNOR-273516 |
| ATR | phosphorylation → down-regulates activity | USP20 | SIGNOR-278393 |
| ATR | phosphorylation → up-regulates activity | USP28 | SIGNOR-275850 |
| ATR | phosphorylation → up-regulates | NBN | SIGNOR-155214 |
| ATR | phosphorylation → up-regulates | FANCD2 | SIGNOR-149305 |
| ATR | phosphorylation → up-regulates activity | CCAR2 | SIGNOR-267662 |
| ATR | phosphorylation → up-regulates activity | AKAP12 | SIGNOR-278292 |
| ATR | phosphorylation → up-regulates activity | RAD17 | SIGNOR-111252 |
| ATR | phosphorylation → up-regulates activity | BRCA1 | SIGNOR-250582 |
| ATR | phosphorylation → up-regulates | ATRIP | SIGNOR-129469 |
| ATR | phosphorylation → up-regulates activity | WDHD1 | SIGNOR-262664 |
| ATR | phosphorylation → down-regulates activity | SIAH1 | SIGNOR-276167 |
| ATR | phosphorylation → up-regulates | XPA | SIGNOR-145190 |
| ATR | phosphorylation → up-regulates | RBBP8 | SIGNOR-200245 |
| ATR | phosphorylation → up-regulates activity | ATM | SIGNOR-150870 |
| ATR | phosphorylation → up-regulates activity | BLM | SIGNOR-278978 |
| ATR | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-115134 |
| ATR | phosphorylation → up-regulates quantity by stabilization | USP20 | SIGNOR-272822 |
| ATR | phosphorylation → up-regulates activity | H2AX | SIGNOR-279356 |
| ATR | phosphorylation down-regulates | CREB1 | SIGNOR-124060 |
| ATR | phosphorylation down-regulates | DBF4 | SIGNOR-177805 |
| ATR | phosphorylation → up-regulates | CHEK1 | SIGNOR-134712 |
| ATR | phosphorylation down-regulates | DBF4 | SIGNOR-177809 |
| ATR | phosphorylation → up-regulates | FANCD2 | SIGNOR-149309 |
| ATR | phosphorylation → up-regulates activity | MCC | SIGNOR-273515 |
| ATR | phosphorylation → up-regulates quantity by stabilization | E2F1 | SIGNOR-109420 |
| ATR | phosphorylation → up-regulates | FANCA | SIGNOR-182953 |
| ATR | phosphorylation → up-regulates activity | BRCA1 | SIGNOR-106436 |
| ATR | phosphorylation → up-regulates activity | BRCA1 | SIGNOR-106432 |
| ATR | phosphorylation → up-regulates | PRKDC | SIGNOR-148722 |
| ATR | phosphorylation → up-regulates | CHEK1 | SIGNOR-134716 |
| ATR | phosphorylation → down-regulates activity | PARP1 | SIGNOR-277551 |
| ATR | phosphorylation → up-regulates activity | USP28 | SIGNOR-275851 |
| ATR | phosphorylation → down-regulates activity | MDM2 | SIGNOR-119546 |
| ATR | phosphorylation → up-regulates activity | BRCA1 | SIGNOR-250583 |
| ATR | phosphorylation → up-regulates | BRCA1 | SIGNOR-201050 |
| ATR | phosphorylation → up-regulates activity | XPA | SIGNOR-258985 |
| ATR | phosphorylation → up-regulates activity | MCC | SIGNOR-273514 |
| ATR | phosphorylation → up-regulates | MCM4 | SIGNOR-169412 |
| ATR | phosphorylation → up-regulates activity | UPF1 | SIGNOR-278911 |
| ATR | phosphorylation → up-regulates activity | PALB2 | SIGNOR-279588 |