Entity Details

Name CAMK2B
ID Q13554
Role kinase
Enzymatic Domains
Protein kinase 14-272
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CAMK2BETS1Ser251GKLGGQDsFESIESYphosphorylation
down-regulates activity
12475968SIGNOR-250684
CAMK2BETS1Ser257DSFESIEsYDSCDRLphosphorylation
down-regulates activity
12475968SIGNOR-250685
CAMK2BETS1Ser282NSLQRVPsYDSFDSEphosphorylation
down-regulates activity
12475968SIGNOR-250686
CAMK2BETS1Ser285QRVPSYDsFDSEDYPphosphorylation
down-regulates activity
12475968SIGNOR-250687
CAMK2BSTMN1Ser16KELEKRAsGQAFELIphosphorylation
down-regulates
9686569SIGNOR-59358
CAMK2BCTNNB1Ser552QDTQRRTsMGGTQQQphosphorylation
down-regulates
24117889SIGNOR-202825
CAMK2BCTNNB1Thr332VNIMRTYtYEKLLWTphosphorylation
down-regulates
24117889SIGNOR-202829
CAMK2BCTNNB1Thr472ICALRHLtSRHQEAEphosphorylation
down-regulates
24117889SIGNOR-202833
CAMK2BSTAT1Ser727TDNLLPMsPEEFDEVphosphorylation
up-regulates
17502367SIGNOR-154771
CAMK2BGSK3ASer21SGRARTSsFAEPGGGphosphorylation
down-regulates
20841359SIGNOR-167962
CAMK2BPLCB3Ser537PSLEPQKsLGDEGLNphosphorylation
unknown
11325525SIGNOR-250689
CAMK2BPRKAA1Thr183SDGEFLRtSCGSPNYphosphorylation
up-regulates
15980064SIGNOR-138360
CAMK2BGRIN2BSer1303NKLRRQHsYDTFVDLphosphorylation
up-regulates activity
8940188SIGNOR-250688
CAMK2BCAMK2BThr287 SMMHRQEtVECLKKFphosphorylation
up-regulates activity
2842767SIGNOR-250640
CAMK2BSCN5ASer516LSLTRGLsRTSMKPRphosphorylation
up-regulates activity
33410863SIGNOR-275773
CAMK2BSCN5ASer571PWPLRRTsAQGQPSPphosphorylation
up-regulates activity
33410863SIGNOR-275774
CAMK2BSCN5AThr594LHGKKNStVDCNGVVphosphorylation
up-regulates activity
33410863SIGNOR-275775
CAMK2BRETREG1Ser151AQLWRSLsESWEVINphosphorylation
up-regulates activity
31930741SIGNOR-273554
CAMK2BCYLDSer362FYTLNGSsVDSQPQSphosphorylation
up-regulates
24614225SIGNOR-25334
CAMK2BCYLDSer772LFKKIFPsLELNITDphosphorylation
up-regulates
24614225SIGNOR-91403
CAMK2BCYLDSer418TTENRFHsLPFSLTKphosphorylation
up-regulates activity
24614225SIGNOR-25329
CAMK2BGABBR1Ser868ITRGEWQsEAQDTMKphosphorylation
down-regulates quantity by destabilization
37686242SIGNOR-277851
CAMK2BGABBR1Thr873WQSEAQDtMKTGSSTphosphorylation
down-regulates quantity by destabilization
37686242SIGNOR-277850
CAMK2BSCN8ASer561PFLSRHNsKSSIFSFphosphorylation
up-regulates activity
32611770SIGNOR-275787
CAMK2BSCN8ASer641RRSVKRNsTVDCNGVphosphorylation
up-regulates activity
32611770SIGNOR-275788
CAMK2BSCN8AThr642RSVKRNStVDCNGVVphosphorylation
up-regulates activity
32611770SIGNOR-275789
CAMK2BAMPKphosphorylation
up-regulates
15980064SIGNOR-217493
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CAMK2Bphosphorylation
up-regulates
ETS1
PSer251
phosphorylation
down-regulates
ETS112475968SIGNOR-250684
CAMK2Bphosphorylation
up-regulates
ETS1
PSer257
phosphorylation
down-regulates
ETS112475968SIGNOR-250685
CAMK2Bphosphorylation
up-regulates
ETS1
PSer282
phosphorylation
down-regulates
ETS112475968SIGNOR-250686
CAMK2Bphosphorylation
up-regulates
ETS1
PSer285
phosphorylation
down-regulates
ETS112475968SIGNOR-250687
CAMK2Bphosphorylation
up-regulates
STMN1
PSer16
phosphorylation
down-regulates
STMN19686569SIGNOR-59358
CAMK2Bphosphorylation
up-regulates
CTNNB1
PSer552
phosphorylation
down-regulates
CTNNB124117889SIGNOR-202825
CAMK2Bphosphorylation
up-regulates
CTNNB1
PThr332
phosphorylation
down-regulates
CTNNB124117889SIGNOR-202829
CAMK2Bphosphorylation
up-regulates
CTNNB1
PThr472
phosphorylation
down-regulates
CTNNB124117889SIGNOR-202833
CAMK2Bphosphorylation
up-regulates
STAT1
PSer727
phosphorylation
up-regulates
STAT117502367SIGNOR-154771
CAMK2Bphosphorylation
up-regulates
GSK3A
PSer21
phosphorylation
down-regulates
GSK3A20841359SIGNOR-167962
CAMK2Bphosphorylation
up-regulates
PLCB3
PSer537
phosphorylation
down-regulates
PLCB311325525SIGNOR-250689
CAMK2Bphosphorylation
up-regulates
PRKAA1
PThr183
phosphorylation
up-regulates
PRKAA115980064SIGNOR-138360
CAMK2Bphosphorylation
up-regulates
GRIN2B
PSer1303
phosphorylation
up-regulates
GRIN2B8940188SIGNOR-250688
CAMK2Bphosphorylation
up-regulates
CAMK2B
PThr287
phosphorylation
up-regulates
CAMK2B2842767SIGNOR-250640
CAMK2Bphosphorylation
up-regulates
SCN5A
PSer516
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275773
CAMK2Bphosphorylation
up-regulates
SCN5A
PSer571
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275774
CAMK2Bphosphorylation
up-regulates
SCN5A
PThr594
phosphorylation
up-regulates
SCN5A33410863SIGNOR-275775
CAMK2Bphosphorylation
up-regulates
RETREG1
PSer151
phosphorylation
up-regulates
RETREG131930741SIGNOR-273554
CAMK2Bphosphorylation
up-regulates
CYLD
PSer362
phosphorylation
up-regulates
CYLD24614225SIGNOR-25334
CAMK2Bphosphorylation
up-regulates
CYLD
PSer772
phosphorylation
up-regulates
CYLD24614225SIGNOR-91403
CAMK2Bphosphorylation
up-regulates
CYLD
PSer418
phosphorylation
up-regulates
CYLD24614225SIGNOR-25329
CAMK2Bphosphorylation
up-regulates
GABBR1
PSer868
phosphorylation
down-regulates
GABBR137686242SIGNOR-277851
CAMK2Bphosphorylation
up-regulates
GABBR1
PThr873
phosphorylation
down-regulates
GABBR137686242SIGNOR-277850
CAMK2Bphosphorylation
up-regulates
SCN8A
PSer561
phosphorylation
up-regulates
SCN8A32611770SIGNOR-275787
CAMK2Bphosphorylation
up-regulates
SCN8A
PSer641
phosphorylation
up-regulates
SCN8A32611770SIGNOR-275788
CAMK2Bphosphorylation
up-regulates
SCN8A
PThr642
phosphorylation
up-regulates
SCN8A32611770SIGNOR-275789
Regulator Mechanism/Effect Target SIGNOR-ID
CAMK2Bphosphorylation

down-regulates activity
ETS1SIGNOR-250684
CAMK2Bphosphorylation

down-regulates activity
ETS1SIGNOR-250685
CAMK2Bphosphorylation

down-regulates activity
ETS1SIGNOR-250686
CAMK2Bphosphorylation

down-regulates activity
ETS1SIGNOR-250687
CAMK2Bphosphorylation
img/direct_inhibition.png
down-regulates
STMN1SIGNOR-59358
CAMK2Bphosphorylation
img/direct_inhibition.png
down-regulates
CTNNB1SIGNOR-202825
CAMK2Bphosphorylation
img/direct_inhibition.png
down-regulates
CTNNB1SIGNOR-202829
CAMK2Bphosphorylation
img/direct_inhibition.png
down-regulates
CTNNB1SIGNOR-202833
CAMK2Bphosphorylation

up-regulates
STAT1SIGNOR-154771
CAMK2Bphosphorylation
img/direct_inhibition.png
down-regulates
GSK3ASIGNOR-167962
CAMK2Bphosphorylation

unknown
PLCB3SIGNOR-250689
CAMK2Bphosphorylation

up-regulates
PRKAA1SIGNOR-138360
CAMK2Bphosphorylation

up-regulates activity
GRIN2BSIGNOR-250688
CAMK2Bphosphorylation

up-regulates activity
CAMK2BSIGNOR-250640
CAMK2Bphosphorylation

up-regulates activity
SCN5ASIGNOR-275773
CAMK2Bphosphorylation

up-regulates activity
SCN5ASIGNOR-275774
CAMK2Bphosphorylation

up-regulates activity
SCN5ASIGNOR-275775
CAMK2Bphosphorylation

up-regulates activity
RETREG1SIGNOR-273554
CAMK2Bphosphorylation

up-regulates
CYLDSIGNOR-25334
CAMK2Bphosphorylation

up-regulates
CYLDSIGNOR-91403
CAMK2Bphosphorylation

up-regulates activity
CYLDSIGNOR-25329
CAMK2Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
GABBR1SIGNOR-277851
CAMK2Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
GABBR1SIGNOR-277850
CAMK2Bphosphorylation

up-regulates activity
SCN8ASIGNOR-275787
CAMK2Bphosphorylation

up-regulates activity
SCN8ASIGNOR-275788
CAMK2Bphosphorylation

up-regulates activity
SCN8ASIGNOR-275789
CAMK2Bphosphorylation

up-regulates
AMPKSIGNOR-217493