| Name | CAMK2G |
| ID | Q13555 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 14-272 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2G | MAP3K7 | – | phosphorylation up-regulates | 12482967 | SIGNOR-96422 | |
| CAMK2G | ADCY3 | Ser1076 | NVASRMEsTGVMGNI | phosphorylation down-regulates activity | 8798667 | SIGNOR-250691 |
| CAMK2G | EGFR | Ser1070 | DSFLQRYsSDPTGAL | phosphorylation down-regulates activity | 1309762 | SIGNOR-250694 |
| CAMK2G | EGFR | Ser1071 | SFLQRYSsDPTGALT | phosphorylation down-regulates activity | 1309762 | SIGNOR-250695 |
| CAMK2G | TH | Ser19 | KGFRRAVsELDAKQA | phosphorylation up-regulates activity | 1680128 | SIGNOR-250709 |
| CAMK2G | SYN1 | Ser568 | PQATRQTsVSGPAPP | phosphorylation unknown | 3118371 | SIGNOR-250707 |
| CAMK2G | SYN1 | Ser605 | AGPTRQAsQAGPVPR | phosphorylation unknown | 3118371 | SIGNOR-250708 |
| CAMK2G | ATF1 | Ser63 | GILARRPsYRKILKD | phosphorylation up-regulates activity | 8663317 | SIGNOR-250692 |
| CAMK2G | FLNA | Ser2523 | VTGPRLVsNHSLHET | phosphorylation unknown | 11290523 | SIGNOR-250696 |
| CAMK2G | RYR1 | Ser2843 | KKKTRKIsQSAQTYD | phosphorylation unknown | 8380342 | SIGNOR-250704 |
| CAMK2G | CHAT | Thr574 | VDNIRSAtPEALAFV | phosphorylation up-regulates activity | 12486117 | SIGNOR-250693 |
| CAMK2G | SPR | Ser213 | QQLARETsVDPDMRK | phosphorylation unknown | 11825621 | SIGNOR-250705 |
| CAMK2G | STAT1 | Ser727 | TDNLLPMsPEEFDEV | phosphorylation up-regulates activity | 11972023 | SIGNOR-250706 |
| CAMK2G | GRIA1 | Ser849 | FCLIPQQsINEAIRT | phosphorylation up-regulates activity | 12609872 | SIGNOR-250698 |
| CAMK2G | GRIA1 | Ser645 | LTVERMVsPIESAED | phosphorylation up-regulates activity | 7877986 | SIGNOR-250697 |
| CAMK2G | GRIA4 | Ser862 | IRNKARLsITGSVGE | phosphorylation unknown | 10366608 | SIGNOR-250699 |
| CAMK2G | RRAD | Ser273 | AGTRRREsLGKKAKR | phosphorylation unknown | 9677319 | SIGNOR-250703 |
| CAMK2G | PLCB3 | Ser537 | PSLEPQKsLGDEGLN | phosphorylation unknown | 11325525 | SIGNOR-250702 |
| CAMK2G | SCN5A | Ser516 | LSLTRGLsRTSMKPR | phosphorylation up-regulates activity | 33410863 | SIGNOR-275779 |
| CAMK2G | SCN5A | Ser571 | PWPLRRTsAQGQPSP | phosphorylation up-regulates activity | 33410863 | SIGNOR-275780 |
| CAMK2G | SCN5A | Thr594 | LHGKKNStVDCNGVV | phosphorylation up-regulates activity | 33410863 | SIGNOR-275781 |
| CAMK2G | PEA15 | Ser116 | KDIIRQPsEEEIIKL | phosphorylation unknown | 9721757 | SIGNOR-250701 |
| CAMK2G | MYLK | Ser1760 | RAIGRLSsMAMISGL | phosphorylation down-regulates activity | 2160950 | SIGNOR-250700 |
| CAMK2G | FBXO43 | – | phosphorylation down-regulates activity | 25546390 | SIGNOR-280200 | |
| CAMK2G | SCN8A | Ser561 | PFLSRHNsKSSIFSF | phosphorylation up-regulates activity | 32611770 | SIGNOR-275793 |
| CAMK2G | SCN8A | Ser641 | RRSVKRNsTVDCNGV | phosphorylation up-regulates activity | 32611770 | SIGNOR-275794 |
| CAMK2G | SCN8A | Thr642 | RSVKRNStVDCNGVV | phosphorylation up-regulates activity | 32611770 | SIGNOR-275795 |
| CAMK2G | HDAC5 | Ser259 | FPLRKTAsEPNLKVR | phosphorylation down-regulates | 11114197 | SIGNOR-85098 |
| CAMK2G | HDAC5 | Ser498 | RPLSRTQsSPLPQSP | phosphorylation down-regulates | 11114197 | SIGNOR-85102 |
| CAMK2G | NCOR2 | Ser2407 | AKVSGRPsSRKAKSP | phosphorylation down-regulates | 22888005 | SIGNOR-191777 |
| CAMK2G | AMPA | – | phosphorylation up-regulates activity | 12609872 | SIGNOR-270234 | |
| CAMK2G | Adenylate_cyclase | Ser1076 | NVASRMEsTGVMGNI | phosphorylation down-regulates activity | 8798667 | SIGNOR-267845 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2G | phosphorylation up-regulates → | ADCY3 PSer1076 | phosphorylation down-regulates ⊣ | ADCY3 | 8798667 | SIGNOR-250691 |
| CAMK2G | phosphorylation up-regulates → | EGFR PSer1070 | phosphorylation down-regulates ⊣ | EGFR | 1309762 | SIGNOR-250694 |
| CAMK2G | phosphorylation up-regulates → | EGFR PSer1071 | phosphorylation down-regulates ⊣ | EGFR | 1309762 | SIGNOR-250695 |
| CAMK2G | phosphorylation up-regulates → | TH PSer19 | phosphorylation up-regulates → | TH | 1680128 | SIGNOR-250709 |
| CAMK2G | phosphorylation up-regulates → | SYN1 PSer568 | phosphorylation down-regulates ⊣ | SYN1 | 3118371 | SIGNOR-250707 |
| CAMK2G | phosphorylation up-regulates → | SYN1 PSer605 | phosphorylation down-regulates ⊣ | SYN1 | 3118371 | SIGNOR-250708 |
| CAMK2G | phosphorylation up-regulates → | ATF1 PSer63 | phosphorylation up-regulates → | ATF1 | 8663317 | SIGNOR-250692 |
| CAMK2G | phosphorylation up-regulates → | FLNA PSer2523 | phosphorylation down-regulates ⊣ | FLNA | 11290523 | SIGNOR-250696 |
| CAMK2G | phosphorylation up-regulates → | RYR1 PSer2843 | phosphorylation down-regulates ⊣ | RYR1 | 8380342 | SIGNOR-250704 |
| CAMK2G | phosphorylation up-regulates → | CHAT PThr574 | phosphorylation up-regulates → | CHAT | 12486117 | SIGNOR-250693 |
| CAMK2G | phosphorylation up-regulates → | SPR PSer213 | phosphorylation down-regulates ⊣ | SPR | 11825621 | SIGNOR-250705 |
| CAMK2G | phosphorylation up-regulates → | STAT1 PSer727 | phosphorylation up-regulates → | STAT1 | 11972023 | SIGNOR-250706 |
| CAMK2G | phosphorylation up-regulates → | GRIA1 PSer849 | phosphorylation up-regulates → | GRIA1 | 12609872 | SIGNOR-250698 |
| CAMK2G | phosphorylation up-regulates → | GRIA1 PSer645 | phosphorylation up-regulates → | GRIA1 | 7877986 | SIGNOR-250697 |
| CAMK2G | phosphorylation up-regulates → | GRIA4 PSer862 | phosphorylation down-regulates ⊣ | GRIA4 | 10366608 | SIGNOR-250699 |
| CAMK2G | phosphorylation up-regulates → | RRAD PSer273 | phosphorylation down-regulates ⊣ | RRAD | 9677319 | SIGNOR-250703 |
| CAMK2G | phosphorylation up-regulates → | PLCB3 PSer537 | phosphorylation down-regulates ⊣ | PLCB3 | 11325525 | SIGNOR-250702 |
| CAMK2G | phosphorylation up-regulates → | SCN5A PSer516 | phosphorylation up-regulates → | SCN5A | 33410863 | SIGNOR-275779 |
| CAMK2G | phosphorylation up-regulates → | SCN5A PSer571 | phosphorylation up-regulates → | SCN5A | 33410863 | SIGNOR-275780 |
| CAMK2G | phosphorylation up-regulates → | SCN5A PThr594 | phosphorylation up-regulates → | SCN5A | 33410863 | SIGNOR-275781 |
| CAMK2G | phosphorylation up-regulates → | PEA15 PSer116 | phosphorylation down-regulates ⊣ | PEA15 | 9721757 | SIGNOR-250701 |
| CAMK2G | phosphorylation up-regulates → | MYLK PSer1760 | phosphorylation down-regulates ⊣ | MYLK | 2160950 | SIGNOR-250700 |
| CAMK2G | phosphorylation up-regulates → | SCN8A PSer561 | phosphorylation up-regulates → | SCN8A | 32611770 | SIGNOR-275793 |
| CAMK2G | phosphorylation up-regulates → | SCN8A PSer641 | phosphorylation up-regulates → | SCN8A | 32611770 | SIGNOR-275794 |
| CAMK2G | phosphorylation up-regulates → | SCN8A PThr642 | phosphorylation up-regulates → | SCN8A | 32611770 | SIGNOR-275795 |
| CAMK2G | phosphorylation up-regulates → | HDAC5 PSer259 | phosphorylation down-regulates ⊣ | HDAC5 | 11114197 | SIGNOR-85098 |
| CAMK2G | phosphorylation up-regulates → | HDAC5 PSer498 | phosphorylation down-regulates ⊣ | HDAC5 | 11114197 | SIGNOR-85102 |
| CAMK2G | phosphorylation up-regulates → | NCOR2 PSer2407 | phosphorylation down-regulates ⊣ | NCOR2 | 22888005 | SIGNOR-191777 |
| CAMK2G | phosphorylation up-regulates → | Adenylate PSer1076 | phosphorylation down-regulates ⊣ | Adenylate | 8798667 | SIGNOR-267845 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CAMK2G | phosphorylation → up-regulates | MAP3K7 | SIGNOR-96422 |
| CAMK2G | phosphorylation → down-regulates activity | ADCY3 | SIGNOR-250691 |
| CAMK2G | phosphorylation → down-regulates activity | EGFR | SIGNOR-250694 |
| CAMK2G | phosphorylation → down-regulates activity | EGFR | SIGNOR-250695 |
| CAMK2G | phosphorylation → up-regulates activity | TH | SIGNOR-250709 |
| CAMK2G | phosphorylation → unknown | SYN1 | SIGNOR-250707 |
| CAMK2G | phosphorylation → unknown | SYN1 | SIGNOR-250708 |
| CAMK2G | phosphorylation → up-regulates activity | ATF1 | SIGNOR-250692 |
| CAMK2G | phosphorylation → unknown | FLNA | SIGNOR-250696 |
| CAMK2G | phosphorylation → unknown | RYR1 | SIGNOR-250704 |
| CAMK2G | phosphorylation → up-regulates activity | CHAT | SIGNOR-250693 |
| CAMK2G | phosphorylation → unknown | SPR | SIGNOR-250705 |
| CAMK2G | phosphorylation → up-regulates activity | STAT1 | SIGNOR-250706 |
| CAMK2G | phosphorylation → up-regulates activity | GRIA1 | SIGNOR-250698 |
| CAMK2G | phosphorylation → up-regulates activity | GRIA1 | SIGNOR-250697 |
| CAMK2G | phosphorylation → unknown | GRIA4 | SIGNOR-250699 |
| CAMK2G | phosphorylation → unknown | RRAD | SIGNOR-250703 |
| CAMK2G | phosphorylation → unknown | PLCB3 | SIGNOR-250702 |
| CAMK2G | phosphorylation → up-regulates activity | SCN5A | SIGNOR-275779 |
| CAMK2G | phosphorylation → up-regulates activity | SCN5A | SIGNOR-275780 |
| CAMK2G | phosphorylation → up-regulates activity | SCN5A | SIGNOR-275781 |
| CAMK2G | phosphorylation → unknown | PEA15 | SIGNOR-250701 |
| CAMK2G | phosphorylation → down-regulates activity | MYLK | SIGNOR-250700 |
| CAMK2G | phosphorylation → down-regulates activity | FBXO43 | SIGNOR-280200 |
| CAMK2G | phosphorylation → up-regulates activity | SCN8A | SIGNOR-275793 |
| CAMK2G | phosphorylation → up-regulates activity | SCN8A | SIGNOR-275794 |
| CAMK2G | phosphorylation → up-regulates activity | SCN8A | SIGNOR-275795 |
| CAMK2G | phosphorylation down-regulates | HDAC5 | SIGNOR-85098 |
| CAMK2G | phosphorylation down-regulates | HDAC5 | SIGNOR-85102 |
| CAMK2G | phosphorylation down-regulates | NCOR2 | SIGNOR-191777 |
| CAMK2G | phosphorylation → up-regulates activity | AMPA | SIGNOR-270234 |
| CAMK2G | phosphorylation → down-regulates activity | Adenylate_cyclase | SIGNOR-267845 |