Summary

Name CAMK2G
Full Name Calcium/calmodulin-dependent protein kinase type II subunit gamma
Synonyms CaM kinase II subunit gamma, CaMK-II subunit gamma | CAMK, CAMK-II, CAMKG
Primary ID Q13555
Links - -
Type protein
Relations 24
Function Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation EGFR 0.09
Publications: 2 Organism: , Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation ADCY3
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation PEA15 0.41
Publications: 1
+ down-regulates activity img/direct_inhibition.png phosphorylation MYLK 0.29
Publications: 1
+ up-regulates activity img/direct-activation.png phosphorylation TH 0.15
Publications: 1
+ img/unknown.png phosphorylation SPR 0.33
Publications: 1
+ down-regulates img/direct_inhibition.png phosphorylation NCOR2 0.18
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation FLNA 0.43
Publications: 1
+ down-regulates img/direct_inhibition.png phosphorylation HDAC5
Publications: 2 Organism: Homo Sapiens
Tissue: Muscle
+ img/unknown.png phosphorylation RRAD 0.25
Publications: 1
+ img/unknown.png phosphorylation RYR1 0.11
Publications: 1
+ img/unknown.png phosphorylation PLCB3 0.43
Publications: 1
+ img/unknown.png phosphorylation SYN1 0.20
Publications: 2
+ up-regulates activity img/direct-activation.png phosphorylation ATF1 0.30
Publications: 1
+ up-regulates activity img/direct-activation.png phosphorylation GRIA1 0.35
Publications: 2
+ up-regulates activity img/direct-activation.png phosphorylation STAT1 0.36
Publications: 1
+ img/unknown.png phosphorylation GRIA4 0.26
Publications: 1
+ up-regulates activity img/direct-activation.png phosphorylation CHAT 0.17
Publications: 1
+ up-regulates img/direct-activation.png chemical activation CAMK2G
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation MAP3K7 0.36
Publications: 1 Organism: Homo Sapiens