Entity Details

Name IKBKB_Ser446
ID Q13568
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
IKBKBIRF5Ser446DSIRLQIsNPDLKDRphosphorylation
up-regulates activity		25326420SIGNOR-279466
RIPK2IRF5Ser446DSIRLQIsNPDLKDRphosphorylation
up-regulates		22412986SIGNOR-196524
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
IKBKBphosphorylation
up-regulates
→
IRF5
PSer446		phosphorylation
up-regulates
→		IRF525326420SIGNOR-279466
RIPK2phosphorylation
up-regulates
→
IRF5
PSer446		phosphorylation
up-regulates
→		IRF522412986SIGNOR-196524
Regulator Mechanism/Effect Target SIGNOR-ID
IKBKBphosphorylation
→
up-regulates activity 		IRF5SIGNOR-279466
RIPK2phosphorylation
→
up-regulates 		IRF5SIGNOR-196524