Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
TBK1	IRF5	Ser158 View in OncoXplorer	QRMLPSLsLTEDVKW	phosphorylation up-regulates	22412986	SIGNOR-196528

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
TBK1	phosphorylation up-regulates →	IRF5 PSer158	phosphorylation up-regulates →	IRF5	22412986	SIGNOR-196528

Regulator	Mechanism/Effect	Target	SIGNOR-ID
TBK1	phosphorylation → up-regulates	IRF5	SIGNOR-196528