Entity Details

Name STIM1
ID Q13586
Role substrate
Enzymatic Domains
EF-hand 1 64-97
PubMed
EF-hand 2 102-126
PubMed
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1STIM1Ser668 IGEETDSsPGRKKFPphosphorylation
down-regulates
19881501SIGNOR-189017
MAPK1STIM1Ser575 LVEKLPDsPALAKKAphosphorylation
up-regulates
22298426SIGNOR-192788
PRKAG2STIM1Ser257 GLHRAEQsLHDLQERphosphorylation
down-regulates activity
31381180SIGNOR-277297
FAM20CSTIM1Ser88GDVDVEEsDEFLREDphosphorylation
up-regulates activity
30520731SIGNOR-279173
PRKAB1STIM1Ser257 GLHRAEQsLHDLQERphosphorylation
down-regulates activity
31381180SIGNOR-277298
PAK1STIM1phosphorylation
up-regulates activity
29780159SIGNOR-279244
PRKAA1STIM1Ser257 GLHRAEQsLHDLQERphosphorylation
down-regulates activity
31381180SIGNOR-277299
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
STIM1
PSer668
phosphorylation
down-regulates
STIM119881501SIGNOR-189017
MAPK1phosphorylation
up-regulates
STIM1
PSer575
phosphorylation
up-regulates
STIM122298426SIGNOR-192788
PRKAG2phosphorylation
up-regulates
STIM1
PSer257
phosphorylation
down-regulates
STIM131381180SIGNOR-277297
FAM20Cphosphorylation
up-regulates
STIM1
PSer88
phosphorylation
up-regulates
STIM130520731SIGNOR-279173
PRKAB1phosphorylation
up-regulates
STIM1
PSer257
phosphorylation
down-regulates
STIM131381180SIGNOR-277298
PRKAA1phosphorylation
up-regulates
STIM1
PSer257
phosphorylation
down-regulates
STIM131381180SIGNOR-277299
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
img/direct_inhibition.png
down-regulates
STIM1SIGNOR-189017
MAPK1phosphorylation

up-regulates
STIM1SIGNOR-192788
PRKAG2phosphorylation

down-regulates activity
STIM1SIGNOR-277297
FAM20Cphosphorylation

up-regulates activity
STIM1SIGNOR-279173
PRKAB1phosphorylation

down-regulates activity
STIM1SIGNOR-277298
PAK1phosphorylation

up-regulates activity
STIM1SIGNOR-279244
PRKAA1phosphorylation

down-regulates activity
STIM1SIGNOR-277299