| Name | DYRK1A |
| ID | Q13627 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 159-479 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1A | FOXO1 | – | phosphorylation down-regulates | 19188143 | SIGNOR-183670 | |
| DYRK1A | CASP9 | Thr125 | PEVLRPEtPRPVDIG | phosphorylation down-regulates activity | 19016842 | SIGNOR-279326 |
| DYRK1A | FOXO4 | – | phosphorylation down-regulates | 19188143 | SIGNOR-183677 | |
| DYRK1A | FOXO | Ser330 | RLSPIMAsTELDEVQ | phosphorylation down-regulates activity | 19188143 | SIGNOR-252906 |
| DYRK1A | SIRT2 | – | phosphorylation up-regulates activity | 22876196 | SIGNOR-279990 | |
| DYRK1A | STAT3 | Ser727 | NTIDLPMsPRTLDSL | phosphorylation up-regulates activity | 31454149 | SIGNOR-279992 |
| DYRK1A | FOXO3 | Ser330 | RLSPIMAsTELDEVQ | phosphorylation down-regulates | 19188143 | SIGNOR-183674 |
| DYRK1A | AMPH | Ser295 | PARPRSPsQTRKGPP | phosphorylation down-regulates | 16733250 | SIGNOR-146906 |
| DYRK1A | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates | 20696760 | SIGNOR-167407 |
| DYRK1A | AMPH | Thr310 | VPPLPKVtPTKELQQ | phosphorylation down-regulates | 16733250 | SIGNOR-146910 |
| DYRK1A | MAP3K5 | – | phosphorylation up-regulates activity | 22110360 | SIGNOR-279366 | |
| DYRK1A | IRS1 | Ser312 | TESITATsPASMVGG | phosphorylation up-regulates quantity | 31723029 | SIGNOR-279520 |
| DYRK1A | MEF2D | Ser251 | NKVIPAKsPPPPTHS | phosphorylation down-regulates activity | 34109727 | SIGNOR-277901 |
| DYRK1A | MCL1 | Ser159 | NNTSTDGsLPSTPPP | phosphorylation up-regulates quantity | 32587776 | SIGNOR-279704 |
| DYRK1A | SPRY2 | Thr75 | KPAPRPStQHKHERL | phosphorylation down-regulates | 18678649 | SIGNOR-179828 |
| DYRK1A | IRS1 | Ser616 | DDGYMPMsPGVAPVP | phosphorylation up-regulates quantity | 31723029 | SIGNOR-279521 |
| DYRK1A | GYS1 | Ser641 | YRYPRPAsVPPSPSL | phosphorylation down-regulates activity | 14593110 | SIGNOR-260632 |
| DYRK1A | SRSF1 | Ser238 | SRGSPRYsPRHSRSR | phosphorylation unknown | 18658135 | SIGNOR-179615 |
| DYRK1A | NFATC1 | Ser278 | NGRQPPYsPHHSPTP | phosphorylation up-regulates activity | 28235034 | SIGNOR-278278 |
| DYRK1A | CCND1 | Thr286 | EEVDLACtPTDVRDV | phosphorylation down-regulates | 24119401 | SIGNOR-202838 |
| DYRK1A | SRSF6 | – | phosphorylation up-regulates activity | 27049307 | SIGNOR-279166 | |
| DYRK1A | GRIN2A | Ser1048 | NRTHSLKsPRYLPEE | phosphorylation up-regulates quantity | 25368549 | SIGNOR-279327 |
| DYRK1A | TOMM70 | Ser91 | KTPEGRAsPAPGSGH | phosphorylation up-regulates activity | 34257281 | SIGNOR-279994 |
| DYRK1A | SF3B1 | Thr434 | PARKLTAtPTPLGGM | phosphorylation unknown | 16512921 | SIGNOR-144975 |
| DYRK1A | MAP1A | – | phosphorylation up-regulates activity | 22514676 | SIGNOR-279032 | |
| DYRK1A | MAPT | Thr529 | TPGSRSRtPSLPTPP | phosphorylation down-regulates | 21215781 | SIGNOR-171038 |
| DYRK1A | RCAN1 | Ser167 | FLISPPAsPPVGWKQ | phosphorylation up-regulates | 16126726 | SIGNOR-139958 |
| DYRK1A | AMPH | Ser276 | PLPSPTAsPNHTLAP | phosphorylation down-regulates | 15262992 | SIGNOR-126847 |
| DYRK1A | GLI1 | – | phosphorylation up-regulates | 12138125 | SIGNOR-90809 | |
| DYRK1A | DYRK1A | Tyr321 | LGQRIYQyIQSRFYR | phosphorylation up-regulates activity | 11672423 | SIGNOR-111145 |
| DYRK1A | CCNL2 | Ser330 | LDGTSGFsPAPKLVE | phosphorylation unknown | 14623875 | SIGNOR-251087 |
| DYRK1A | NOTCH | – | phosphorylation down-regulates | 19383720 | SIGNOR-254313 | |
| DYRK1A | DNM1 | Ser857 | ASPSRPEsPRPPFDL | phosphorylation down-regulates | 15287745 | SIGNOR-127444 |
| DYRK1A | AMPH | Ser293 | PAPARPRsPSQTRKG | phosphorylation down-regulates activity | 16733250 | SIGNOR-146902 |
| DYRK1A | DYRK1A | Tyr319 | CQLGQRIyQYIQSRF | phosphorylation up-regulates | 10910078 | SIGNOR-79760 |
| DYRK1A | NFATC1 | Ser409 | LSPTSYMsPTLPALD | phosphorylation up-regulates activity | 28235034 | SIGNOR-278276 |
| DYRK1A | FOXO | – | phosphorylation down-regulates | 19188143 | SIGNOR-252905 | |
| DYRK1A | SRSF2 | – | phosphorylation down-regulates activity | 21470964 | SIGNOR-278307 | |
| DYRK1A | PLK2 | Ser358 | VPDFHLSsPAKNFFK | phosphorylation up-regulates quantity by stabilization | 37387444 | SIGNOR-277791 |
| DYRK1A | NFATC1 | Ser261 | ARSSRPAsPCNKRKY | phosphorylation up-regulates activity | 28235034 | SIGNOR-278279 |
| DYRK1A | LIN52 | Ser28 | FEKLDRAsPDLWPEQ | phosphorylation up-regulates activity | 21498570 | SIGNOR-262846 |
| DYRK1A | NOTCH1 | – | phosphorylation down-regulates | 19383720 | SIGNOR-185494 | |
| DYRK1A | SNCA | Ser87 | KTVEGAGsIAAATGF | phosphorylation up-regulates | 16959772 | SIGNOR-149393 |
| DYRK1A | AMPH | Ser285 | NHTLAPAsPAPARPR | phosphorylation down-regulates | 15262992 | SIGNOR-126851 |
| DYRK1A | GLI1 | Ser408 | GPLPRAPsISTVEPK | phosphorylation up-regulates activity | 28735864 | SIGNOR-278930 |
| DYRK1A | CCNL2 | Ser369 | AKKAKADsPVNGLPK | phosphorylation unknown | 14623875 | SIGNOR-251089 |
| DYRK1A | AMPH | Thr310 | VPPLPKVtPTKELQQ | phosphorylation down-regulates | 15262992 | SIGNOR-126855 |
| DYRK1A | CDKN1B | Ser10 | NVRVSNGsPSLERMD | phosphorylation up-regulates activity | 24806449 | SIGNOR-278250 |
| DYRK1A | MEF2D | Ser251 | NKVIPAKsPPPPTHS | phosphorylation down-regulates activity | 34109727 | SIGNOR-277565 |
| DYRK1A | CCNL2 | Ser338 | PAPKLVEsPKEGKGS | phosphorylation unknown | 14623875 | SIGNOR-251088 |
| DYRK1A | FOXO6 | – | phosphorylation down-regulates | 19188143 | SIGNOR-183680 | |
| DYRK1A | MAPT | Ser519 | SGYSSPGsPGTPGSR | phosphorylation down-regulates | 21215781 | SIGNOR-171030 |
| DYRK1A | SIRT1 | Thr530 | YLSELPPtPLHVSED | phosphorylation up-regulates activity | 20167603 | SIGNOR-278473 |
| DYRK1A | PLK2 | Ser358 | VPDFHLSsPAKNFFK | phosphorylation up-regulates quantity by stabilization | 37387444 | SIGNOR-277805 |
| DYRK1A | FOXO | Ser329 | STISGRLsPIMTEQD | phosphorylation down-regulates activity | 11311120 | SIGNOR-252909 |
| DYRK1A | AMPH | Ser272 | EEPSPLPsPTASPNH | phosphorylation down-regulates | 15262992 | SIGNOR-126843 |
| DYRK1A | FOXO | Ser330 | RLSPIMAsTELDEVQ | phosphorylation down-regulates | 19188143 | SIGNOR-252907 |
| DYRK1A | MAPT | Ser721 | PVVSGDTsPRHLSNV | phosphorylation down-regulates | 21215781 | SIGNOR-171034 |
| DYRK1A | NFATC1 | Ser403 | WAKPKPLsPTSYMSP | phosphorylation up-regulates activity | 28235034 | SIGNOR-278277 |
| DYRK1A | FOXO1 | Ser329 | STISGRLsPIMTEQD | phosphorylation down-regulates activity | 11311120 | SIGNOR-106829 |
| DYRK1A | MCL1 | Thr163 | TDGSLPStPPPAEEE | phosphorylation up-regulates quantity | 32587776 | SIGNOR-279703 |
| DYRK1A | DYRK1A | Tyr321 | LGQRIYQyIQSRFYR | phosphorylation up-regulates | 10910078 | SIGNOR-79764 |
| DYRK1A | DNM1 | Ser795 | VPPARPGsRGPAPGP | phosphorylation down-regulates | 15287745 | SIGNOR-127440 |
| DYRK1A | MYC | Ser62 | S-->E | phosphorylation down-regulates quantity | 24901999 | SIGNOR-279609 |
| DYRK1A | FOXO3 | Ser330 | RLSPIMAsTELDEVQ | phosphorylation down-regulates activity | 19188143 | SIGNOR-106833 |
| DYRK1A | AMPH | Ser262 | LRIAKTPsPPEEPSP | phosphorylation down-regulates | 15262992 | SIGNOR-126839 |
| DYRK1A | RCAN1 | Ser167 | FLISPPAsPPVGWKQ | phosphorylation up-regulates | 12809556 | SIGNOR-102290 |
| DYRK1A | DYRK1A | Ser529 | SNSGRARsDPTHQHR | phosphorylation up-regulates activity | 17229891 | SIGNOR-251090 |
| DYRK1A | CREB1 | – | phosphorylation up-regulates activity | 22110360 | SIGNOR-279989 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1A | phosphorylation up-regulates → | CASP9 PThr125 | phosphorylation down-regulates ⊣ | CASP9 | 19016842 | SIGNOR-279326 |
| DYRK1A | phosphorylation up-regulates → | FOXO PSer330 | phosphorylation down-regulates ⊣ | FOXO | 19188143 | SIGNOR-252906 |
| DYRK1A | phosphorylation up-regulates → | STAT3 PSer727 | phosphorylation up-regulates → | STAT3 | 31454149 | SIGNOR-279992 |
| DYRK1A | phosphorylation up-regulates → | FOXO3 PSer330 | phosphorylation down-regulates ⊣ | FOXO3 | 19188143 | SIGNOR-183674 |
| DYRK1A | phosphorylation up-regulates → | AMPH PSer295 | phosphorylation down-regulates ⊣ | AMPH | 16733250 | SIGNOR-146906 |
| DYRK1A | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 20696760 | SIGNOR-167407 |
| DYRK1A | phosphorylation up-regulates → | AMPH PThr310 | phosphorylation down-regulates ⊣ | AMPH | 16733250 | SIGNOR-146910 |
| DYRK1A | phosphorylation up-regulates → | IRS1 PSer312 | phosphorylation up-regulates → | IRS1 | 31723029 | SIGNOR-279520 |
| DYRK1A | phosphorylation up-regulates → | MEF2D PSer251 | phosphorylation down-regulates ⊣ | MEF2D | 34109727 | SIGNOR-277901 |
| DYRK1A | phosphorylation up-regulates → | MCL1 PSer159 | phosphorylation up-regulates → | MCL1 | 32587776 | SIGNOR-279704 |
| DYRK1A | phosphorylation up-regulates → | SPRY2 PThr75 | phosphorylation down-regulates ⊣ | SPRY2 | 18678649 | SIGNOR-179828 |
| DYRK1A | phosphorylation up-regulates → | IRS1 PSer616 | phosphorylation up-regulates → | IRS1 | 31723029 | SIGNOR-279521 |
| DYRK1A | phosphorylation up-regulates → | GYS1 PSer641 | phosphorylation down-regulates ⊣ | GYS1 | 14593110 | SIGNOR-260632 |
| DYRK1A | phosphorylation up-regulates → | SRSF1 PSer238 | phosphorylation down-regulates ⊣ | SRSF1 | 18658135 | SIGNOR-179615 |
| DYRK1A | phosphorylation up-regulates → | NFATC1 PSer278 | phosphorylation up-regulates → | NFATC1 | 28235034 | SIGNOR-278278 |
| DYRK1A | phosphorylation up-regulates → | CCND1 PThr286 | phosphorylation down-regulates ⊣ | CCND1 | 24119401 | SIGNOR-202838 |
| DYRK1A | phosphorylation up-regulates → | GRIN2A PSer1048 | phosphorylation up-regulates → | GRIN2A | 25368549 | SIGNOR-279327 |
| DYRK1A | phosphorylation up-regulates → | TOMM70 PSer91 | phosphorylation up-regulates → | TOMM70 | 34257281 | SIGNOR-279994 |
| DYRK1A | phosphorylation up-regulates → | SF3B1 PThr434 | phosphorylation down-regulates ⊣ | SF3B1 | 16512921 | SIGNOR-144975 |
| DYRK1A | phosphorylation up-regulates → | MAPT PThr529 | phosphorylation down-regulates ⊣ | MAPT | 21215781 | SIGNOR-171038 |
| DYRK1A | phosphorylation up-regulates → | RCAN1 PSer167 | phosphorylation up-regulates → | RCAN1 | 16126726 | SIGNOR-139958 |
| DYRK1A | phosphorylation up-regulates → | AMPH PSer276 | phosphorylation down-regulates ⊣ | AMPH | 15262992 | SIGNOR-126847 |
| DYRK1A | phosphorylation up-regulates → | DYRK1A PTyr321 | phosphorylation up-regulates → | DYRK1A | 11672423 | SIGNOR-111145 |
| DYRK1A | phosphorylation up-regulates → | CCNL2 PSer330 | phosphorylation down-regulates ⊣ | CCNL2 | 14623875 | SIGNOR-251087 |
| DYRK1A | phosphorylation up-regulates → | DNM1 PSer857 | phosphorylation down-regulates ⊣ | DNM1 | 15287745 | SIGNOR-127444 |
| DYRK1A | phosphorylation up-regulates → | AMPH PSer293 | phosphorylation down-regulates ⊣ | AMPH | 16733250 | SIGNOR-146902 |
| DYRK1A | phosphorylation up-regulates → | DYRK1A PTyr319 | phosphorylation up-regulates → | DYRK1A | 10910078 | SIGNOR-79760 |
| DYRK1A | phosphorylation up-regulates → | NFATC1 PSer409 | phosphorylation up-regulates → | NFATC1 | 28235034 | SIGNOR-278276 |
| DYRK1A | phosphorylation up-regulates → | PLK2 PSer358 | phosphorylation up-regulates → | PLK2 | 37387444 | SIGNOR-277791 |
| DYRK1A | phosphorylation up-regulates → | NFATC1 PSer261 | phosphorylation up-regulates → | NFATC1 | 28235034 | SIGNOR-278279 |
| DYRK1A | phosphorylation up-regulates → | LIN52 PSer28 | phosphorylation up-regulates → | LIN52 | 21498570 | SIGNOR-262846 |
| DYRK1A | phosphorylation up-regulates → | SNCA PSer87 | phosphorylation up-regulates → | SNCA | 16959772 | SIGNOR-149393 |
| DYRK1A | phosphorylation up-regulates → | AMPH PSer285 | phosphorylation down-regulates ⊣ | AMPH | 15262992 | SIGNOR-126851 |
| DYRK1A | phosphorylation up-regulates → | GLI1 PSer408 | phosphorylation up-regulates → | GLI1 | 28735864 | SIGNOR-278930 |
| DYRK1A | phosphorylation up-regulates → | CCNL2 PSer369 | phosphorylation down-regulates ⊣ | CCNL2 | 14623875 | SIGNOR-251089 |
| DYRK1A | phosphorylation up-regulates → | AMPH PThr310 | phosphorylation down-regulates ⊣ | AMPH | 15262992 | SIGNOR-126855 |
| DYRK1A | phosphorylation up-regulates → | CDKN1B PSer10 | phosphorylation up-regulates → | CDKN1B | 24806449 | SIGNOR-278250 |
| DYRK1A | phosphorylation up-regulates → | MEF2D PSer251 | phosphorylation down-regulates ⊣ | MEF2D | 34109727 | SIGNOR-277565 |
| DYRK1A | phosphorylation up-regulates → | CCNL2 PSer338 | phosphorylation down-regulates ⊣ | CCNL2 | 14623875 | SIGNOR-251088 |
| DYRK1A | phosphorylation up-regulates → | MAPT PSer519 | phosphorylation down-regulates ⊣ | MAPT | 21215781 | SIGNOR-171030 |
| DYRK1A | phosphorylation up-regulates → | SIRT1 PThr530 | phosphorylation up-regulates → | SIRT1 | 20167603 | SIGNOR-278473 |
| DYRK1A | phosphorylation up-regulates → | PLK2 PSer358 | phosphorylation up-regulates → | PLK2 | 37387444 | SIGNOR-277805 |
| DYRK1A | phosphorylation up-regulates → | FOXO PSer329 | phosphorylation down-regulates ⊣ | FOXO | 11311120 | SIGNOR-252909 |
| DYRK1A | phosphorylation up-regulates → | AMPH PSer272 | phosphorylation down-regulates ⊣ | AMPH | 15262992 | SIGNOR-126843 |
| DYRK1A | phosphorylation up-regulates → | FOXO PSer330 | phosphorylation down-regulates ⊣ | FOXO | 19188143 | SIGNOR-252907 |
| DYRK1A | phosphorylation up-regulates → | MAPT PSer721 | phosphorylation down-regulates ⊣ | MAPT | 21215781 | SIGNOR-171034 |
| DYRK1A | phosphorylation up-regulates → | NFATC1 PSer403 | phosphorylation up-regulates → | NFATC1 | 28235034 | SIGNOR-278277 |
| DYRK1A | phosphorylation up-regulates → | FOXO1 PSer329 | phosphorylation down-regulates ⊣ | FOXO1 | 11311120 | SIGNOR-106829 |
| DYRK1A | phosphorylation up-regulates → | MCL1 PThr163 | phosphorylation up-regulates → | MCL1 | 32587776 | SIGNOR-279703 |
| DYRK1A | phosphorylation up-regulates → | DYRK1A PTyr321 | phosphorylation up-regulates → | DYRK1A | 10910078 | SIGNOR-79764 |
| DYRK1A | phosphorylation up-regulates → | DNM1 PSer795 | phosphorylation down-regulates ⊣ | DNM1 | 15287745 | SIGNOR-127440 |
| DYRK1A | phosphorylation up-regulates → | MYC PSer62 | phosphorylation down-regulates ⊣ | MYC | 24901999 | SIGNOR-279609 |
| DYRK1A | phosphorylation up-regulates → | FOXO3 PSer330 | phosphorylation down-regulates ⊣ | FOXO3 | 19188143 | SIGNOR-106833 |
| DYRK1A | phosphorylation up-regulates → | AMPH PSer262 | phosphorylation down-regulates ⊣ | AMPH | 15262992 | SIGNOR-126839 |
| DYRK1A | phosphorylation up-regulates → | RCAN1 PSer167 | phosphorylation up-regulates → | RCAN1 | 12809556 | SIGNOR-102290 |
| DYRK1A | phosphorylation up-regulates → | DYRK1A PSer529 | phosphorylation up-regulates → | DYRK1A | 17229891 | SIGNOR-251090 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| DYRK1A | phosphorylation down-regulates | FOXO1 | SIGNOR-183670 |
| DYRK1A | phosphorylation → down-regulates activity | CASP9 | SIGNOR-279326 |
| DYRK1A | phosphorylation down-regulates | FOXO4 | SIGNOR-183677 |
| DYRK1A | phosphorylation → down-regulates activity | FOXO | SIGNOR-252906 |
| DYRK1A | phosphorylation → up-regulates activity | SIRT2 | SIGNOR-279990 |
| DYRK1A | phosphorylation → up-regulates activity | STAT3 | SIGNOR-279992 |
| DYRK1A | phosphorylation down-regulates | FOXO3 | SIGNOR-183674 |
| DYRK1A | phosphorylation down-regulates | AMPH | SIGNOR-146906 |
| DYRK1A | phosphorylation → up-regulates | TP53 | SIGNOR-167407 |
| DYRK1A | phosphorylation down-regulates | AMPH | SIGNOR-146910 |
| DYRK1A | phosphorylation → up-regulates activity | MAP3K5 | SIGNOR-279366 |
| DYRK1A | phosphorylation → up-regulates quantity | IRS1 | SIGNOR-279520 |
| DYRK1A | phosphorylation → down-regulates activity | MEF2D | SIGNOR-277901 |
| DYRK1A | phosphorylation → up-regulates quantity | MCL1 | SIGNOR-279704 |
| DYRK1A | phosphorylation down-regulates | SPRY2 | SIGNOR-179828 |
| DYRK1A | phosphorylation → up-regulates quantity | IRS1 | SIGNOR-279521 |
| DYRK1A | phosphorylation → down-regulates activity | GYS1 | SIGNOR-260632 |
| DYRK1A | phosphorylation → unknown | SRSF1 | SIGNOR-179615 |
| DYRK1A | phosphorylation → up-regulates activity | NFATC1 | SIGNOR-278278 |
| DYRK1A | phosphorylation down-regulates | CCND1 | SIGNOR-202838 |
| DYRK1A | phosphorylation → up-regulates activity | SRSF6 | SIGNOR-279166 |
| DYRK1A | phosphorylation → up-regulates quantity | GRIN2A | SIGNOR-279327 |
| DYRK1A | phosphorylation → up-regulates activity | TOMM70 | SIGNOR-279994 |
| DYRK1A | phosphorylation → unknown | SF3B1 | SIGNOR-144975 |
| DYRK1A | phosphorylation → up-regulates activity | MAP1A | SIGNOR-279032 |
| DYRK1A | phosphorylation down-regulates | MAPT | SIGNOR-171038 |
| DYRK1A | phosphorylation → up-regulates | RCAN1 | SIGNOR-139958 |
| DYRK1A | phosphorylation down-regulates | AMPH | SIGNOR-126847 |
| DYRK1A | phosphorylation → up-regulates | GLI1 | SIGNOR-90809 |
| DYRK1A | phosphorylation → up-regulates activity | DYRK1A | SIGNOR-111145 |
| DYRK1A | phosphorylation → unknown | CCNL2 | SIGNOR-251087 |
| DYRK1A | phosphorylation down-regulates | NOTCH | SIGNOR-254313 |
| DYRK1A | phosphorylation down-regulates | DNM1 | SIGNOR-127444 |
| DYRK1A | phosphorylation → down-regulates activity | AMPH | SIGNOR-146902 |
| DYRK1A | phosphorylation → up-regulates | DYRK1A | SIGNOR-79760 |
| DYRK1A | phosphorylation → up-regulates activity | NFATC1 | SIGNOR-278276 |
| DYRK1A | phosphorylation down-regulates | FOXO | SIGNOR-252905 |
| DYRK1A | phosphorylation → down-regulates activity | SRSF2 | SIGNOR-278307 |
| DYRK1A | phosphorylation → up-regulates quantity by stabilization | PLK2 | SIGNOR-277791 |
| DYRK1A | phosphorylation → up-regulates activity | NFATC1 | SIGNOR-278279 |
| DYRK1A | phosphorylation → up-regulates activity | LIN52 | SIGNOR-262846 |
| DYRK1A | phosphorylation down-regulates | NOTCH1 | SIGNOR-185494 |
| DYRK1A | phosphorylation → up-regulates | SNCA | SIGNOR-149393 |
| DYRK1A | phosphorylation down-regulates | AMPH | SIGNOR-126851 |
| DYRK1A | phosphorylation → up-regulates activity | GLI1 | SIGNOR-278930 |
| DYRK1A | phosphorylation → unknown | CCNL2 | SIGNOR-251089 |
| DYRK1A | phosphorylation down-regulates | AMPH | SIGNOR-126855 |
| DYRK1A | phosphorylation → up-regulates activity | CDKN1B | SIGNOR-278250 |
| DYRK1A | phosphorylation → down-regulates activity | MEF2D | SIGNOR-277565 |
| DYRK1A | phosphorylation → unknown | CCNL2 | SIGNOR-251088 |
| DYRK1A | phosphorylation down-regulates | FOXO6 | SIGNOR-183680 |
| DYRK1A | phosphorylation down-regulates | MAPT | SIGNOR-171030 |
| DYRK1A | phosphorylation → up-regulates activity | SIRT1 | SIGNOR-278473 |
| DYRK1A | phosphorylation → up-regulates quantity by stabilization | PLK2 | SIGNOR-277805 |
| DYRK1A | phosphorylation → down-regulates activity | FOXO | SIGNOR-252909 |
| DYRK1A | phosphorylation down-regulates | AMPH | SIGNOR-126843 |
| DYRK1A | phosphorylation down-regulates | FOXO | SIGNOR-252907 |
| DYRK1A | phosphorylation down-regulates | MAPT | SIGNOR-171034 |
| DYRK1A | phosphorylation → up-regulates activity | NFATC1 | SIGNOR-278277 |
| DYRK1A | phosphorylation → down-regulates activity | FOXO1 | SIGNOR-106829 |
| DYRK1A | phosphorylation → up-regulates quantity | MCL1 | SIGNOR-279703 |
| DYRK1A | phosphorylation → up-regulates | DYRK1A | SIGNOR-79764 |
| DYRK1A | phosphorylation down-regulates | DNM1 | SIGNOR-127440 |
| DYRK1A | phosphorylation → down-regulates quantity | MYC | SIGNOR-279609 |
| DYRK1A | phosphorylation → down-regulates activity | FOXO3 | SIGNOR-106833 |
| DYRK1A | phosphorylation down-regulates | AMPH | SIGNOR-126839 |
| DYRK1A | phosphorylation → up-regulates | RCAN1 | SIGNOR-102290 |
| DYRK1A | phosphorylation → up-regulates activity | DYRK1A | SIGNOR-251090 |
| DYRK1A | phosphorylation → up-regulates activity | CREB1 | SIGNOR-279989 |